Author

Patrick N. Guest

Observed name: Patrick Guest

Institution: University of St Andrews

Observed institution: University of St Andrews

OpenAlex ID: A5084767323

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

2021 · Eliza Yankova, Wesley Blackaby, et al. · Nature · 1,358

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment

2016 · Lukas Hroch, Patrick Guest, et al. · Bioorganic & Medicinal Chemistry · 58

Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment

2016 · Lukas Hroch, Ondrej Benek, et al. · Bioorganic & Medicinal Chemistry Letters · 36

6-Benzothiazolyl Ureas, Thioureas and Guanidines are Potent Inhibitors of ABAD/17β-HSD10 and Potential Drugs for Alzheimer"s Disease Treatment: Design, Synthesis and in vitro Evaluation

2017 · Ondrej Benek, Lukas Hroch, et al. · Medicinal Chemistry · 29

A scan for genes associated with cancer mortality and longevity in pedigree dog breeds

2020 · Aoife Doherty, Inês Lopes, et al. · Mammalian Genome · 21

Condensation properties of stress granules and processing bodies are compromised in myotonic dystrophy type 1

2022 · Selma Gulyurtlu, Monika S. Magon, et al. · Disease Models & Mechanisms · 7

[P1–039]: IN VITRO EVALUATION OF BENZOTHIAZOLE‐BASED UREAS AS POTENTIAL ABAD/17β‐HSD10 MODULATORS FOR ALZHEIMER'S DISEASE THERAPEUTICS

2017 · Laura Aitken, Lukas Hroch, et al. · Alzheimer s & Dementia · 1

[P2–035]: IN VITRO EVALUATION OF BENZOTHIAZOLE‐BASED UREAS AS POTENTIAL ABAD/17β‐HSD10 MODULATORS FOR ALZHEIMER'S DISEASE THERAPEUTICS

2017 · Laura Aitken, Lukas Hroch, et al. · Alzheimer s & Dementia · 1

Author Reply to Peer Reviews of Phase-separated stress granules and processing bodies are compromised in Myotonic Dystrophy Type 1

2021 · Judith E Sleeman, Alan R Prescott, et al.

The identification and characterisation of novel inhibitors of the 17β-HSD10 enzyme for the treatment of Alzheimer's disease

2016 · Patrick Guest · St Andrews Research Repository (St Andrews Research Repository)

P4‐197: Structure‐based Design and Characterisation of Small Molecule Human Abad Inhibitors as Therapeutics in Alzheimers Disease

2014 · Laura Aitken, Patrick Guest, et al. · Alzheimer s & Dementia

Works count: 11

Citation count: 1,511

H-index: 6

I10-index: 5