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Qihong Zhao

Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis
2018 · Mingming Sun, Wei Wu, et al. · Nature Communications · 660
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GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3
2018 · Ye Zhao, Feidi Chen, et al. · Mucosal Immunology · 517
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Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43
2016 · W. Wu, M. Sun, et al. · Mucosal Immunology · 500
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Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain
2019 · James R. Burke, Lihong Cheng, et al. · Science Translational Medicine · 291
Selectivity Profile of the Tyrosine Kinase 2 Inhibitor Deucravacitinib Compared with Janus Kinase 1/2/3 Inhibitors
2021 · Anjaneya Chimalakonda, James Burke, et al. · Dermatology and Therapy · 130
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Dual targeting of CCR2 and CCR5: therapeutic potential for immunologic and cardiovascular diseases
2010 · Qihong Zhao · Journal of Leukocyte Biology · 114
PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment
2022 · Natalie B Collins, Rose Al Abosy, et al. · Journal for ImmunoTherapy of Cancer · 113
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mTOR Mediates IL-23 Induction of Neutrophil IL-17 and IL-22 Production
2016 · Feidi Chen, Anthony Cao, et al. · The Journal of Immunology · 107
The Vav Binding Site (Y315) in ZAP-70 Is Critical for Antigen Receptor–mediated Signal Transduction
1997 · Jun Wu, Qihong Zhao, et al. · The Journal of Experimental Medicine · 104
Enhancement of Lymphocyte Responsiveness by a Gain-of-Function Mutation of ZAP-70
1996 · Qihong Zhao, Arthur Weiss · Molecular and Cellular Biology · 90
IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model
2018 · Bailey Zwarycz, Adam D. Gracz, et al. · Cellular and Molecular Gastroenterology and Hepatology · 89
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GPR120 Inhibits Colitis Through Regulation of CD4+ T Cell Interleukin 10 Production
2021 · Wenjing Yang, Han Liu, et al. · Gastroenterology · 78
CCR2/CCR5 inhibitor permits the radiation-induced effector T cell infiltration in pancreatic adenocarcinoma
2022 · Jianxin Wang, May Tun Saung, et al. · The Journal of Experimental Medicine · 74
A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines
2017 · Qihong Zhao, Taeg Kim, et al. · Journal of Leukocyte Biology · 71
Microbiota Metabolite Short-Chain Fatty Acids Facilitate Mucosal Adjuvant Activity of Cholera Toxin through GPR43
2019 · Wenjing Yang, Yi Xiao, et al. · The Journal of Immunology · 61
Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis
2022 · Tobias Puengel, Sander Lefere, et al. · International Journal of Molecular Sciences · 59
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Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists
2019 · James J.-W. Duan, Zhonghui Lu, et al. · ACS Medicinal Chemistry Letters · 54
Anticancer effect of realgar nanoparticles on mouse melanoma skin cancer in vivo via transdermal drug delivery
2009 · Qi-Hong Zhao, Ying Zhang, et al. · Medical Oncology · 53
BMS-813160: A Potent CCR2 and CCR5 Dual Antagonist Selected as a Clinical Candidate
2021 · Robert J. Cherney, Prakash Anjanappa, et al. · ACS Medicinal Chemistry Letters · 44
Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist
2020 · Robert J. Cherney, Lyndon A. M. Cornelius, et al. · ACS Medicinal Chemistry Letters · 43
Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe
2007 · Percy H. Carter, Rui-Qin Liu, et al. · Proceedings of the National Academy of Sciences · 43
Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
2017 · Hua Gong, David S. Weinstein, et al. · Bioorganic & Medicinal Chemistry Letters · 41
Interdomain B in ZAP-70 Regulates but Is Not Required for ZAP-70 Signaling Function in Lymphocytes
1999 · Qihong Zhao, Brandi L. Williams, et al. · Molecular and Cellular Biology · 39
Rationally Designed, Conformationally Constrained Inverse Agonists of RORγt—Identification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy
2019 · David Marcoux, James J.-W. Duan, et al. · Journal of Medicinal Chemistry · 37
Liquid chromatography coupled with tandem mass spectrometry for the bioanalysis of proteins in drug development: Practical considerations in assay development and validation
2013 · Guowen Liu, Qin C. Ji, et al. · Journal of Chromatography A · 36
Works count: 81
Citation count: 3,939
H-index: 30
I10-index: 44
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