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Author

Michela Puxeddu

Observed name: PUXEDDU, MICHELA
ORCID: 0000-0002-0024-596X
Observed ORCID: 0000-0002-0024-596X
OpenAlex ID: A5084894148
Emerging Therapeutic Agents for Colorectal Cancer
2021 · Marianna Nalli, Michela Puxeddu, et al. · Molecules · 28
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Discovery of Zika Virus NS2B/NS3 Inhibitors That Prevent Mice from Life-Threatening Infection and Brain Damage
2020 · Antonio Coluccia, Michela Puxeddu, et al. · ACS Medicinal Chemistry Letters · 25
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Induction of Ferroptosis in Glioblastoma and Ovarian Cancers by a New Pyrrole Tubulin Assembly Inhibitor
2022 · Michela Puxeddu, Jianchao Wu, et al. · Journal of Medicinal Chemistry · 23
Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia
2021 · Michela Puxeddu, Hongliang Shen, et al. · European Journal of Medicinal Chemistry · 23
Recent Advances in Drug Discovery for Triple-Negative Breast Cancer Treatment
2023 · Domiziana Masci, Chiara Naro, et al. · Molecules · 22
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CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme
2021 · Simona Daniele, Valeria La Pietra, et al. · European Journal of Pharmacology · 21
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Targeting CBP and p300: Emerging Anticancer Agents
2024 · Domiziana Masci, Michela Puxeddu, et al. · Molecules · 20
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4-(3-Phenyl-4-(3,4,5-trimethoxybenzoyl)-1 H -pyrrol-1-yl)benzenesulfonamide, a Novel Carbonic Anhydrase and Wnt/β-Catenin Signaling Pathway Dual-Targeting Inhibitor with Potent Activity against Multidrug Resistant Cancer Cells
2023 · Domiziana Masci, Michela Puxeddu, et al. · Journal of Medicinal Chemistry · 18
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Targeting the Interaction between the SH3 Domain of Grb2 and Gab2
2020 · Francesca Malagrinò, Antonio Coluccia, et al. · Cells · 15
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Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies
2019 · Michela Puxeddu, Hongliang Shen, et al. · European Journal of Medicinal Chemistry · 13
Chemo- and enantio-selective reversed-phase HPLC analysis of rosuvastatin using a cellulose-based chiral stationary phase in gradient elution mode
2023 · Francesca Romana Mammone, Paola Rotundo, et al. · Journal of Pharmaceutical and Biomedical Analysis · 12
Sulfonamide Inhibitors of β‐Catenin Signaling as Anticancer Agents with Different Output on c‐MYC
2020 · Laura Di Magno, Fiorella Di Pastena, et al. · ChemMedChem · 12
Metabolic Rewiring in Cancer: Small Molecule Inhibitors in Colorectal Cancer Therapy
2024 · Domiziana Masci, Michela Puxeddu, et al. · Molecules · 11
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Anticancer Activity of (S)-5-Chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyridin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide (RS4690), a New Dishevelled 1 Inhibitor
2022 · Antonio Coluccia, Marianna Bufano, et al. · Cancers · 11
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Metabolism, a Blossoming Target for Small-Molecule Anticancer Drugs
2025 · Michela Puxeddu, Romano Silvestri, et al. · Molecules · 10
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Novel N-(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the β-Catenin Armadillo Repeats Domain as an Anticancer Agent
2023 · Marianna Nalli, Laura Di Magno, et al. · ACS Pharmacology & Translational Science · 9
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RS6077 Induces Mitotic Arrest and Selectively Activates Cell Death in Human Cancer Cell Lines and in a Lymphoma Tumor In Vivo
2022 · Jessica Sebastiani, Michela Puxeddu, et al. · SSRN Electronic Journal · 9
A Novel Validated UHPLC Method for the Estimation of Rosuvastatin and Its Complete Impurity Profile in Tablet Formulations
2023 · Francesca Romana Mammone, Leo Zanitti, et al. · Molecules · 8
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Ferroptosis Induction by a New Pyrrole Derivative in Triple Negative Breast Cancer and Colorectal Cancer
2025 · Domiziana Masci, Lele Ling, et al. · Journal of Medicinal Chemistry · 5
Targeting the Grb2 cSH3 domain: Design, synthesis and biological evaluation of the first series of modulators
2023 · Marianna Bufano, Michela Puxeddu, et al. · Bioorganic Chemistry · 5
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Development of N -(4-(1 H -Imidazol-1-yl)phenyl)-4-chlorobenzenesulfonamide, a Novel Potent Inhibitor of β-Catenin with Enhanced Antitumor Activity and Metabolic Stability
2024 · Michela Puxeddu, Lele Ling, et al. · Journal of Medicinal Chemistry · 4
Discovery of a Novel Class of Norovirus Inhibitors with High Barrier of Resistance
2021 · Jana Van Dycke, Michela Puxeddu, et al. · Pharmaceuticals · 4
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Discovery of New 1,1′-Biphenyl-4-sulfonamides as Selective Subnanomolar Human Carbonic Anhydrase II Inhibitors
2019 · Giuseppe La Regina, Michela Puxeddu, et al. · ACS Medicinal Chemistry Letters · 4
Microwave-assisted synthesis of tubulin assembly inhibitors as anticancer agents by aryl ring reversal and conjunctive approach
2025 · Domiziana Masci, Michela Puxeddu, et al. · RSC Medicinal Chemistry · 2
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4-(3-Phenylsulfonylindol-2-yl)-1-(pyridin-2-yl)piperazinyl-methanones as Potent Inhibitors of both SARS-CoV-2 and HCoV-OC43 Viruses
2024 · Michela Puxeddu, Manuela Donalisio, et al. · ACS Infectious Diseases · 2
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Works count: 34
Citation count: 317
H-index: 12
I10-index: 15
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