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Úrsula López-García

Observed names: U. Lopez-Garcia, Úrsula López-García, Úrsula López‐García
ORCID: 0000-0003-2557-9584
Observed ORCID: 0000-0003-2557-9584
OpenAlex ID: A5085183855
Structure-Guided Design of Nurr1 Agonists Derived from the Natural Ligand Dihydroxyindole
2023 · Minh Sai, Jan Vietor, et al. · Journal of Medicinal Chemistry · 14
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A Nurr1 Agonist Derived from the Natural Ligand DHI Induces Neuroprotective Gene Expression
2025 · Markus Egner, Romy Busch, et al. · Journal of Medicinal Chemistry · 12
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Rational Design of a New RXR Agonist Scaffold Enabling Single-Subtype Preference for RXRα, RXRβ, and RXRγ
2022 · Gustave Adouvi, Laura Isigkeit, et al. · Journal of Medicinal Chemistry · 12
Structural and mechanistic profiling of Nurr1 modulation by vidofludimus enables structure-guided ligand design
2025 · Úrsula López-García, Jan Vietor, et al. · Communications Chemistry · 7
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Structural Optimization of Oxaprozin for Selective Inverse Nurr1 Agonism
2024 · Sabine Willems, Romy Busch, et al. · Journal of Medicinal Chemistry · 7
Carboxylic Acid Bioisosteres Boost Nurr1 Agonist Selectivity
2025 · Tanja Stiller, Christian Gege, et al. · Journal of Medicinal Chemistry · 5
Structural Tuning of Vidofludimus for High-Efficacy NR4A Agonism
2026 · Jan Vietor, Romy Busch, et al. · Journal of Medicinal Chemistry · 3
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Targeting the SARS-CoV-2 RNA Translation Initiation Element SL1 by Molecules of Low Molecular Weight
2025 · Sabrina Toews, Francesca Donà, et al. · Journal of the American Chemical Society · 3
Systematic Optimization of Fragment TLX Ligands toward Agonism and Inverse Agonism
2026 · Emily C. Hank, Loris Knümann, et al. · Journal of Medicinal Chemistry · 2
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An Activator of Tailless’ Repressor Function Stimulates Anti-Neurodegenerative Gene Expression
2026 · Emily C. Hank, Romy Busch, et al. · Journal of Medicinal Chemistry · 1
Discovery of a First‐in‐Class Dual‐Function TLX Activator by Microscale Library Synthesis and Direct‐to‐Biology Screening
2026 · Tanja Stiller, Romy Busch, et al. · Angewandte Chemie Novit
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Neurosteroids Inhibit RORγ and Induce Major Rearrangement of Its Activation Motif
2026 · Úrsula López-García, Minh Sai, et al. · ACS Chemical Biology
Development of a Brain‐Penetrant Nurr1 Agonist Tool
2026 · Jan Vietor, Tanja Stiller, et al. · ChemMedChem
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Crystal structure of RORg LBD in complex with DHEA
2026 · V. Morozov, U. Lopez-Garcia, et al. · Worldwide Protein Data Bank
Dual Nurr1/RXR Agonism of Valerenic Acid and Synthetic Mimetics Enables Dimer-Selective Nurr1 Modulation
2025 · Katharina Scholz, Úrsula López-García, et al. · ACS Medicinal Chemistry Letters
Works count: 15
Citation count: 66
H-index: 5
I10-index: 3
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