Author

David J. Brockwell

Observed names: Brockwell, D.J, Brockwell, D.J., Brockwell, David, Brockwell, David J., D J Brockwell, D. Brockwell, D. J. Brockwell, D.J. Brockwell, DAVID J. BROCKWELL, David Brockwell, David Brockwell3, David J Brockwell, David J. Brockwell

Institution: University of Leeds

Observed institutions: University of Leeds, Biotechnology and Biological Sciences Research Council, University of Manchester

ORCID: 0000-0002-0802-5937

Observed ORCID: 0000-0002-0802-5937

OpenAlex ID: A5085201520

Pulling geometry defines the mechanical resistance of a β-sheet protein

2003 · David J Brockwell, Emanuele Paci, et al. · Nature Structural & Molecular Biology · 388

Intermediates: ubiquitous species on folding energy landscapes?

2007 · David J Brockwell, Sheena E Radford · Current Opinion in Structural Biology · 222

PDF

A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function

2020 · Ciaran P. A. Doherty, Sabine M. Ulamec, et al. · Nature Structural & Molecular Biology · 206

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

2016 · Matthew G. Iadanza, Anna J. Higgins, et al. · Nature Communications · 200

Tuning the Elastic Modulus of Hydrated Collagen Fibrils

2009 · Colin A. Grant, David J. Brockwell, et al. · Biophysical Journal · 179

PDF

Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria

2020 · Jim E. Horne, David J. Brockwell, et al. · Journal of Biological Chemistry · 177

Mechanically Unfolding the Small, Topologically Simple Protein L

2005 · David J. Brockwell, Godfrey S. Beddard, et al. · Biophysical Journal · 166

PDF

De novo design of transmembrane β barrels

2021 · Anastassia A. Vorobieva, Paul White, et al. · Science · 151

PDF

Effects of hydration on the mechanical response of individual collagen fibrils

2008 · Colin A. Grant, David J. Brockwell, et al. · Applied Physics Letters · 150

The transition state for folding of an outer membrane protein

2010 · Gerard H. M. Huysmans, Stephen A. Baldwin, et al. · Proceedings of the National Academy of Sciences · 138

PyXlinkViewer : A flexible tool for visualization of protein chemical crosslinking data within the PyMOL molecular graphics system

2020 · Bob Schiffrin, Sheena E. Radford, et al. · Protein Science · 137

The Effect of Core Destabilization on the Mechanical Resistance of I27

2002 · David J. Brockwell, Godfrey S. Beddard, et al. · Biophysical Journal · 134

PDF

Protein folding mechanisms: new methods and emerging ideas

2000 · David J Brockwell, D Alastair Smith, et al. · Current Opinion in Structural Biology · 131

Handbook of Single Molecule Fluorescence Spectroscopy

2006 · Chris Gell, David Brockwell, et al. · 127

Force mode atomic force microscopy as a tool for protein folding studies

2003 · Robert B. Best, David J. Brockwell, et al. · Analytica Chimica Acta · 124

Inducing protein aggregation by extensional flow

2017 · John Dobson, Amit Kumar, et al. · Proceedings of the National Academy of Sciences · 115

Looking Beyond the Core: The Role of Flanking Regions in the Aggregation of Amyloidogenic Peptides and Proteins

2020 · Sabine M. Ulamec, David J. Brockwell, et al. · Frontiers in Neuroscience · 109

PDF

Mechanical Resistance of Proteins Explained Using Simple Molecular Models

2005 · Daniel K. West, David J. Brockwell, et al. · Biophysical Journal · 107

PDF

Skp is a multivalent chaperone of outer-membrane proteins

2016 · Bob Schiffrin, Antonio N Calabrese, et al. · Nature Structural & Molecular Biology · 93

PDF

Outer membrane protein folding from an energy landscape perspective

2017 · Bob Schiffrin, David J. Brockwell, et al. · BMC Biology · 89

PDF

An in vivo platform for identifying inhibitors of protein aggregation

2015 · Janet C Saunders, Lydia M Young, et al. · Nature Chemical Biology · 86

PDF

Mechanically unfolding proteins: The effect of unfolding history and the supramolecular scaffold

2002 · Rebecca C. Zinober, David J. Brockwell, et al. · Protein Science · 82

Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding

2017 · Bob Schiffrin, Antonio N. Calabrese, et al. · Journal of Molecular Biology · 80

PDF

Towards design principles for determining the mechanical stability of proteins

2013 · Toni Hoffmann, Katarzyna M. Tych, et al. · Physical Chemistry Chemical Physics · 76

High-throughput directed evolution: a golden era for protein science

2022 · Romany J. McLure, Sheena E. Radford, et al. · Trends in Chemistry · 73

PDF

Works count: 171

Citation count: 5,722

H-index: 43

I10-index: 84