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Leah Officer-Jones
Observed names:
Leah K. Officer,
Leah Officer,
Officer-Jones, Leah
Institutions:
Cancer Research UK,
Cancer Research UK Scotland Institute
Observed institutions:
University of Cambridge,
Cancer Research UK,
Cancer Research UK Scotland Institute,
MRC Toxicology Unit,
University of Glasgow,
Medical Research Council
show all 6
ORCID:
0000-0002-3690-2386
Observed ORCID:
0000-0002-3690-2386
OpenAlex ID:
A5085768301
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma
2020
·
Khalid AbdulJabbar
, Shan E. Ahmed Raza
, et al.
·
Nature Medicine
·
286
PDF
The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer
2021
·
Nour Ghaddar
, Shuo Wang
, et al.
·
Nature Communications
·
79
PDF
The pathogenesis of mesothelioma is driven by a dysregulated translatome
2021
·
Stefano Grosso
, Alberto Marini
, et al.
·
Nature Communications
·
43
PDF
Human-correlated genetic models identify precision therapy for liver cancer
2025
·
Miryam Müller
, Stephanie May
, et al.
·
Nature
·
40
MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance
2025
·
Mark White
, Megan L. Mills
, et al.
·
Nature
·
36
Unbiased cell surface proteomics identifies SEMA4A as an effective immunotherapy target for myeloma
2022
·
Georgina S. F. Anderson
, Jose Ballester-Beltran
, et al.
·
Blood
·
36
In situ growth in early lung adenocarcinoma may represent precursor growth or invasive clone outgrowth—a clinically relevant distinction
2019
·
David Allan Moore
, Marco Sereno
, et al.
·
Modern Pathology
·
35
PDF
Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane
2021
·
Vinaya Phatak
, Yannick von Grabowiecki
, et al.
·
Cell Death and Disease
·
24
PDF
Reduced Protumorigenic Tumor-Associated Macrophages With Statin Use in Premalignant Human Lung Adenocarcinoma
2019
·
Esraa Al Dujaily
, Juvenal Baena
, et al.
·
JNCI Cancer Spectrum
·
17
PDF
Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration
2023
·
Stephanie May
, Miryam Müller
, et al.
·
Journal of Hepatology
·
13
PDF
Analysis of Prostate Cancer Tumor Microenvironment Identifies Reduced Stromal CD4 Effector T-cell Infiltration in Tumors with Pelvic Nodal Metastasis
2021
·
Chara Ntala
, Mark Salji
, et al.
·
European Urology Open Science
·
13
PDF
Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer
2023
·
Phimmada Hatthakarnkul
, Aula Ammar
, et al.
·
Journal of Cancer
·
11
PDF
Mitochondrial double-stranded RNA homeostasis depends on cell-cycle progression
2024
·
Vanessa Xavier
, Silvia Martinelli
, et al.
·
Life Science Alliance
·
9
PDF
Automated Co-in Situ Hybridization and Immunofluorescence Using Archival Tumor Tissue
2020
·
Leah K. Officer
, Kleopatra E. Andreou
, et al.
·
Methods in molecular biology
·
5
Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation
2025
·
Georgios Kanellos
, Chiara Giacomelli
, et al.
·
Nature Genetics
·
4
Inhibiting translation elongation by reducing eIF5A activity induces feedback inhibition of initiation, limiting tumour cell proliferation
2025
·
Aristeidis P. Sfakianos
, Rebecca M. Raven
, et al.
·
Nature Communications
·
4
PDF
A histomorphological atlas of resected mesothelioma discovered by self-supervised learning from 3446 whole-slide images
2025
·
Farzaneh Seyedshahi
, Kai Rakovic
, et al.
·
Nature Communications
·
3
PDF
Morphospatial profiling of cancer-associated fibroblasts reveals architectural subtypes of pancreatic ductal adenocarcinoma
2026
·
Adam S. Bryce
, Silvia Martinelli
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
Self-Supervised AI Reveals a Hidden Landscape of Prognostic Spatial Patterns in Multiplex Immunofluorescence Images
2025
·
Lucas Farndale
, Kai Rakovic
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
PDF
Spatial resolution of transcriptomic plasticity states underpinning lethal morphologies in lung adenocarcinoma
2024
·
Hannah L Williams
, Nicolas Poulain
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
1
mTORC2 stabilizes HIF-1β to coordinate metabolic adaptation in lung cancer
2026
·
Morgane Paque
, Ning An
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
PDF
Additional file 1 of Increased mRNA translation delays tumour initiation and exposes a therapeutic vulnerability in lung cancer
2026
·
Luis Pardo
, Madeleine Moore
, et al.
·
Figshare
Increased mRNA translation delays tumour initiation and exposes a therapeutic vulnerability in lung cancer
2026
·
Luis Pardo
, Madeleine Moore
, et al.
·
Figshare
Increased mRNA translation delays tumour initiation and exposes a therapeutic vulnerability in lung cancer
2026
·
Luis Pardo
, Madeleine Moore
, et al.
·
Molecular Cancer
Phenotype-dependent subtyping exposes high MYC activity as a targetable dependency in LuAd
2026
·
Sarah Laing
, Isabel Dye
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
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Works count:
29
Citation count:
661
H-index:
11
I10-index:
12
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