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Krishnan Raman

Observed names: K. Raman, Raman Krishnan, Raman, Krishnan
ORCID: 0000-0002-6532-2567
Observed ORCID: 0000-0002-6532-2567
OpenAlex ID: A5086033077
Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly
2007 · Norbert Schormann, Alexei Grigorian, et al. · BMC Structural Biology · 42
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Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE)
2021 · Pravin L Kotian, Minwan Wu, et al. · Journal of Medicinal Chemistry · 36
Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores
2009 · Pravin L. Kotian, Raman Krishnan, et al. · Bioorganic & Medicinal Chemistry · 14
Probing the S2 site of factor VIIa to generate potent and selective inhibitors: the structure of BCX-3607 in complex with tissue factor–factor VIIa
2007 · Raman Krishnan, Pravin L. Kotian, et al. · Acta Crystallographica Section D Biological Crystallography · 7
Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors
2022 · Weihe Zhang, Minwan Wu, et al. · Bioorganic & Medicinal Chemistry · 6
Regioselective alkylation of a versatile indazole: Electrophile scope and mechanistic insights from density functional theory calculations
2024 · Pengcheng Lu, Luis Juarez, et al. · Beilstein Journal of Organic Chemistry · 5
Discovery and optimization of orally bioavailable and potent plasma Kallikrein inhibitors bearing a quaternary carbon
2022 · Weihe Zhang, Satish Vadlakonda, et al. · Bioorganic & Medicinal Chemistry · 3
Preclinical Characterization of BCX9930, a Potent Oral Complement Factor D Inhibitor, Targeting Alternative Pathway-Mediated Diseases Including Paroxysmal Nocturnal Hemoglobinuria (PNH)
2020 · Xilin Chen, Xiaogang Cheng, et al. · Blood · 3
Synthesis of novel azasugar-containing 2'β-C-Me 9-deaza nucleosides as potential anti-hepatitis C virus agents
2022 · Pravin L. Kotian, Minwan Wu, et al. · Nucleosides Nucleotides & Nucleic Acids · 1
Corrigendum to “Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores” [Bioorg. Med. Chem. 17 (2009) 3934]
2009 · Pravin L. Kotian, Raman Krishnan, et al. · Bioorganic & Medicinal Chemistry · 1
Absolute Configuration of Key Intermediates and the Gram Scale Synthesis of Berotralstat and ent- Berotralstat
2025 · Pravin L. Kotian, Satish Vadlakonda, et al. · The Journal of Organic Chemistry
Design, synthesis, and structure-activity relationships of selective biphenyl antithrombotic tissue factor/factor VIIa inhibitors
2025 · Pravin L. Kotian, Yahya El-Kattan, et al. · European Journal of Medicinal Chemistry
Works count: 17
Citation count: 118
H-index: 5
I10-index: 3
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