Author

Surabhi Mehra

Observed name: Mehra, Surabhi

Institution: University of Toronto

Observed institutions: Indian Institute of Technology Bombay, University of Toronto, Himachal Pradesh University

ORCID: 0000-0003-1777-673X

Observed ORCID: 0000-0003-1777-673X

OpenAlex ID: A5086114257

α-Synuclein aggregation nucleates through liquid–liquid phase separation

2020 · Soumik Ray, Nitu Singh, et al. · Nature Chemistry · 878

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α-Synuclein misfolding and aggregation: Implications in Parkinson’s disease pathogenesis

2019 · Surabhi Mehra, Shruti Sahay, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 527

α-synuclein aggregation and its modulation

2016 · Dhiman Ghosh, Surabhi Mehra, et al. · International Journal of Biological Macromolecules · 188

p53 amyloid formation leading to its loss of function: implications in cancer pathogenesis

2017 · Saikat Ghosh, Shimul Salot, et al. · Cell Death and Differentiation · 137

Lipopolysaccharide from Gut Microbiota Modulates α-Synuclein Aggregation and Alters Its Biological Function

2019 · Dipita Bhattacharyya, Ganesh M. Mohite, et al. · ACS Chemical Neuroscience · 116

Structural and Functional Insights into α-Synuclein Fibril Polymorphism

2021 · Surabhi Mehra, Laxmikant Gadhe, et al. · Biomolecules · 111

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Glycosaminoglycans have variable effects on α-synuclein aggregation and differentially affect the activities of the resulting amyloid fibrils

2018 · Surabhi Mehra, Dhiman Ghosh, et al. · Journal of Biological Chemistry · 74

Comparison of Kinetics, Toxicity, Oligomer Formation, and Membrane Binding Capacity of α-Synuclein Familial Mutations at the A53 Site, Including the Newly Discovered A53V Mutation

2018 · Ganesh M. Mohite, Rakesh Kumar, et al. · Biochemistry · 59

Cytotoxic Oligomers and Fibrils Trapped in a Gel‐like State of α‐Synuclein Assemblies

2018 · Rakesh Kumar, Subhadeep Das, et al. · Angewandte Chemie International Edition · 41

Multitude NMR studies of α-synuclein familial mutants: probing their differential aggregation propensities

2018 · Dipita Bhattacharyya, Rakesh Kumar, et al. · Chemical Communications · 38

Parkinson’s Disease Associated α-Synuclein Familial Mutants Promote Dopaminergic Neuronal Death in Drosophila melanogaster

2018 · Ganesh M. Mohite, Saumya Dwivedi, et al. · ACS Chemical Neuroscience · 35

The Familial α-Synuclein A53E Mutation Enhances Cell Death in Response to Environmental Toxins Due to a Larger Population of Oligomers

2018 · Ganesh M. Mohite, Ambuja Navalkar, et al. · Biochemistry · 26

α-Synuclein Aggregation Intermediates form Fibril Polymorphs with Distinct Prion-like Properties

2022 · Surabhi Mehra, Sahil Ahlawat, et al. · Journal of Molecular Biology · 25

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The G51D SNCA mutation generates a slowly progressive α-synuclein strain in early-onset Parkinson’s disease

2023 · Heather H. C. Lau, Ivan Martinez-Valbuena, et al. · Acta Neuropathologica Communications · 23

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Direct Demonstration of Seed Size-Dependent α-Synuclein Amyloid Amplification

2022 · Arunima Sakunthala, Debalina Datta, et al. · The Journal of Physical Chemistry Letters · 20

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Complexation of NAC-Derived Peptide Ligands with the C-Terminus of α-Synuclein Accelerates Its Aggregation

2017 · Narendra Nath Jha, Srivastav Ranganathan, et al. · Biochemistry · 19

Co-aggregation and secondary nucleation in the life cycle of human prolactin/galanin functional amyloids

2022 · Debdeep Chatterjee, Reeba S Jacob, et al. · eLife · 18

Effect of Disease-Associated P123H and V70M Mutations on β-Synuclein Fibrillation

2020 · Karan Sharma, Surabhi Mehra, et al. · ACS Chemical Neuroscience · 14

Convergent generation of atypical prions in knockin mouse models of genetic prion disease

2024 · Surabhi Mehra, Matthew E.C. Bourkas, et al. · Journal of Clinical Investigation · 13

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Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease

2024 · Daniel J. Walsh, Judy R. Rees, et al. · PLoS Pathogens · 13

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α-Synuclein purification significantly impacts seed amplification assay performance and consistency

2025 · Zaid A. M. Al-Azzawi, Nicholas R. G. Silver, et al. · Acta Neuropathologica Communications · 9

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The molecular determinants of a universal prion acceptor

2024 · Hamza Arshad, Zeel Patel, et al. · PLoS Pathogens · 9

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Solid-state NMR assignment of α-synuclein polymorph prepared from helical intermediate

2024 · Sahil Ahlawat, Surabhi Mehra, et al. · Biomolecular NMR Assignments · 7

The brain interactome of a permissive prion replication substrate

2025 · Hamza Arshad, Shehab Eid, et al. · Neurobiology of Disease · 6

α‐Synuclein Spontaneously Adopts Stable and Reversible α‐Helical Structure in Water‐Less Environment

2019 · Anasua Mukhopadhyay, Surabhi Mehra, et al. · ChemPhysChem · 6

Works count: 35

Citation count: 2,421

H-index: 17

I10-index: 20