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Felix M. Kluxen

A Review of Recent Advances in Benchmark Dose Methodology
2019 · Signe M. Jensen, Felix M. Kluxen, et al. · Risk Analysis · 72
Molecular effects of ER alpha- and beta-selective agonists on regulation of energy homeostasis in obese female Wistar rats
2013 · Carmen Weigt, Torsten Hertrampf, et al. · Molecular and Cellular Endocrinology · 68
ER -specific agonists and genistein inhibit proliferation and induce apoptosis in the large and small intestine
2011 · B. Schleipen, T. Hertrampf, et al. · Carcinogenesis · 53
Cadmium modulates expression of aryl hydrocarbon receptor-associated genes in rat uterus by interaction with the estrogen receptor
2011 · Felix M. Kluxen, Nicola Höfer, et al. · Archives of Toxicology · 49
Investigations on the estrogenic activity of the metallohormone cadmium in the rat intestine
2010 · Nicola Höfer, Patrick Diel, et al. · Archives of Toxicology · 45
Using historical control data in bioassays for regulatory toxicology
2021 · Felix M. Kluxen, Klaus Weber, et al. · Regulatory Toxicology and Pharmacology · 44
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Genistein modulates the anti-tumor activity of cisplatin in MCF-7 breast and HT-29 colon cancer cells
2014 · Xiao-Juan Hu, Ming-Yong Xie, et al. · Archives of Toxicology · 40
Lifelong exposure to dietary isoflavones reduces risk of obesity in ovariectomized Wistar rats
2015 · Anne Kurrat, Tina Blei, et al. · Molecular Nutrition & Food Research · 35
Compounded conservatism in European re-entry worker risk assessment of pesticides
2021 · Felix M. Kluxen, Edgars Felkers, et al. · Regulatory Toxicology and Pharmacology · 33
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bmd : an R package for benchmark dose estimation
2020 · Signe M. Jensen, Felix M. Kluxen, et al. · PeerJ · 29
Assessment of an extended dataset of in vitro human dermal absorption studies on pesticides to determine default values, opportunities for read-across and influence of dilution on absorption
2015 · M. Aggarwal, P. Fisher, et al. · Regulatory Toxicology and Pharmacology · 29
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The metallohormone cadmium modulates AhR-associated gene expression in the small intestine of rats similar to ethinyl-estradiol
2012 · Felix M. Kluxen, Patrick Diel, et al. · Archives of Toxicology · 27
“New statistics” in regulatory toxicology?
2020 · Felix M. Kluxen · Regulatory Toxicology and Pharmacology · 20
Alternatives to statistical decision trees in regulatory (eco-)toxicological bioassays
2020 · Felix M. Kluxen, Ludwig A. Hothorn · Archives of Toxicology · 20
Understanding and overcoming the technical challenges in using in silico predictions in regulatory decisions of complex toxicological endpoints – A pesticide perspective for regulatory toxicologists with a focus on machine learning models
2022 · Lyle D. Burgoon, Felix M. Kluxen, et al. · Regulatory Toxicology and Pharmacology · 18
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Metribuzin-induced non-adverse liver changes result in rodent-specific non-adverse thyroid effects via uridine 5′-diphospho-glucuronosyltransferase (UDPGT, UGT) modulation
2021 · Werner Bomann, Helen Tinwell, et al. · Regulatory Toxicology and Pharmacology · 17
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Sub-structure-based category formation for the prioritisation of genotoxicity hazard assessment for pesticide residues: Sulphonyl ureas
2022 · S.J. Enoch, Z. Hasarova, et al. · Regulatory Toxicology and Pharmacology · 16
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Scatter plotting as a simple tool to analyse relative organ to body weight in toxicological bioassays
2019 · Felix M. Kluxen · Archives of Toxicology · 16
Dermal absorption study OECD TG 428 mass balance recommendations based on the EFSA database
2019 · Felix M. Kluxen, Sébastien Grégoire, et al. · Regulatory Toxicology and Pharmacology · 14
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The database makes the poison: How the selection of datasets in QSAR models impacts toxicant prediction of higher tier endpoints
2024 · Lyle D. Burgoon, Felix M. Kluxen, et al. · Regulatory Toxicology and Pharmacology · 12
Assessing in vitro dermal absorption of dry residues of agrochemical sprays using human skin within OECD TG 428
2019 · M. Aggarwal, P. Fisher, et al. · Regulatory Toxicology and Pharmacology · 12
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Expanding the toxicologist's statistical toolbox: Using effect size estimation and dose-response modelling for holistic assessments instead of generic testing
2021 · Felix M. Kluxen, Signe M. Jensen · Regulatory Toxicology and Pharmacology · 11
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A new conceptional model for deriving average dermal absorption estimates from studies with multiple tested concentrations for non-dietary risk assessment of pesticides
2022 · Felix M. Kluxen, Edgars Felkers, et al. · Archives of Toxicology · 10
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Robust multiple comparisons against a control group with application in toxicology
2019 · Hothorn, Ludwig A., Kluxen, Felix M. · arXiv (Cornell University) · 10
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Benchmark dose modelling in regulatory ecotoxicology, a potential tool in pest management
2021 · Signe M. Jensen, Felix M. Kluxen, et al. · Pest Management Science · 9
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Works count: 70
Citation count: 832
H-index: 16
I10-index: 24
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