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Tautvydas Karvelis
Observed names:
Karvelis, Tautvydas,
T. Karvelis
Institution:
Vilnius University
Observed institution:
Vilnius University
ORCID:
0000-0002-0685-2947
Observed ORCID:
0000-0002-0685-2947
OpenAlex ID:
A5086762395
Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
2014
·
Mark D. Szczelkun
, Maria S. Tikhomirova
, et al.
·
Proceedings of the National Academy of Sciences
·
456
PDF
Transposon-associated TnpB is a programmable RNA-guided DNA endonuclease
2021
·
Tautvydas Karvelis
, Gytis Druteika
, et al.
·
Nature
·
354
PDF
PAM recognition by miniature CRISPR–Cas12f nucleases triggers programmable double-stranded DNA target cleavage
2020
·
Tautvydas Karvelis
, Greta Bigelyte
, et al.
·
Nucleic Acids Research
·
354
PDF
crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus
2013
·
Tautvydas Karvelis
, Giedrius Gasiunas
, et al.
·
RNA Biology
·
259
PDF
Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements
2015
·
Tautvydas Karvelis
, Giedrius Gasiunas
, et al.
·
Genome biology
·
229
PDF
A catalogue of biochemically diverse CRISPR-Cas9 orthologs
2020
·
Giedrius Gasiunas
, Joshua K. Young
, et al.
·
Nature Communications
·
177
PDF
An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis
2023
·
Tomohiro Hino
, Satoshi N. Omura
, et al.
·
Cell
·
132
Miniature type V-F CRISPR-Cas nucleases enable targeted DNA modification in cells
2021
·
Greta Bigelyte
, Joshua K. Young
, et al.
·
Nature Communications
·
114
PDF
TnpB structure reveals minimal functional core of Cas12 nuclease family
2023
·
Giedrius Sasnauskas
, Giedre Tamulaitiene
, et al.
·
Nature
·
97
5′ modifications to CRISPR–Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage
2020
·
Grace Mullally
, Kara van Aelst
, et al.
·
Nucleic Acids Research
·
48
PDF
Methods for decoding Cas9 protospacer adjacent motif (PAM) sequences: A brief overview
2017
·
Tautvydas Karvelis
, Giedrius Gasiunas
, et al.
·
Methods
·
38
Harnessing the natural diversity and in vitro evolution of Cas9 to expand the genome editing toolbox
2017
·
Tautvydas Karvelis
, Giedrius Gasiunas
, et al.
·
Current Opinion in Microbiology
·
33
Targeted gene editing by transfection ofin vitroreconstitutedStreptococcus thermophilusCas9 nuclease complex
2015
·
Monika Glemzaite
, Egle Balciunaite
, et al.
·
RNA Biology
·
33
Programmable DNA cleavage in vitro by Cas9
2013
·
Tautvydas Karvelis
, Giedrius Gasiunas
, et al.
·
Biochemical Society Transactions
·
29
Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing
2024
·
Greta Bigelyte
, Brigita Duchovska
, et al.
·
Nucleic Acids Research
·
23
PDF
PAM recognition by miniature CRISPR nucleases triggers programmable double-stranded DNA target cleavage
2019
·
Tautvydas Karvelis
, Greta Bigelyte
, et al.
·
bioRxiv (Cold Spring Harbor Laboratory)
·
20
PDF
A pipeline for characterization of novel Cas9 orthologs
2018
·
Tautvydas Karvelis
, Joshua K. Young
, et al.
·
Methods in enzymology on CD-ROM/Methods in enzymology
·
17
Oriented Soft DNA Curtains for Single-Molecule Imaging
2021
·
Aurimas Kopu̅stas
, Šaru̅nė Ivanovaitė
, et al.
·
Langmuir
·
13
Directed evolution of compact RNA-guided nucleases for enhanced activity in mammalian cells
2026
·
Fedor Gorbenko
, Irene Sala
, et al.
·
Genome biology
·
3
Off-target detection of CRISPR-Cas9 nuclease in vitro with CROFT-Seq
2026
·
Paulius Toliusis
, Algirdas Grybauskas
, et al.
·
Synthetic Biology
·
2
Structural and mechanistic insights into the sequential dsDNA cleavage by SpCas12f1
2025
·
Julene Madariaga-Marcos
, Marius Baltramonaitis
, et al.
·
Nucleic Acids Research
·
2
PDF
Mis-annotation of TnpB: case of TaRGET-ABE
2023
·
Tautvydas Karvelis
, Virginijus Siksnys
·
Nature Chemical Biology
·
2
Experimental strategy for characterization of novel TnpB orthologs
2025
·
Gytis Druteika
, Tautvydas Karvelis
, et al.
·
Methods in enzymology on CD-ROM/Methods in enzymology
·
1
Fanzors: Mysterious TnpB-Like Bacterial Transposon-Related RNA-Guided DNA Nucleases of Eukaryotes
2023
·
Tautvydas Karvelis
, Virginijus Siksnys
·
The CRISPR Journal
·
1
Additional file 2 of Directed evolution of compact RNA-guided nucleases for enhanced activity in mammalian cells
2026
·
Fedor Gorbenko
, Irene Sala
, et al.
·
Figshare
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Works count:
44
Citation count:
2,438
H-index:
17
I10-index:
18
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