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John A. Broadwater

Peroxodiferric Intermediate of Stearoyl-Acyl Carrier Protein Δ9 Desaturase: Oxidase Reactivity during Single Turnover and Implications for the Mechanism of Desaturation
1998 · John A. Broadwater, Jingyuan Ai, et al. · Biochemistry · 207
A structural role for arginine in proteins: Multiple hydrogen bonds to backbone carbonyl oxygens
1994 · C.L. Borders, John A. Broadwater, et al. · Protein Science · 203
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Desaturation and Hydroxylation
2002 · John A. Broadwater, Edward Whittle, et al. · Journal of Biological Chemistry · 165
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Lactose Fed-Batch Overexpression of Recombinant Metalloproteins in Escherichia coli BL21(DE3): Process Control Yielding High Levels of Metal-Incorporated, Soluble Protein
1995 · B.J. Hoffman, J.A. Broadwater, et al. · Protein Expression and Purification · 109
Mössbauer Studies of the Formation and Reactivity of a Quasi-Stable Peroxo Intermediate of Stearoyl-Acyl Carrier Protein Δ9-Desaturase
1999 · John A. Broadwater, Catalina Achim, et al. · Biochemistry · 102
Circular Dichroism and Magnetic Circular Dichroism Studies of the Reduced Binuclear Non-Heme Iron Site of Stearoyl-ACP Δ9-Desaturase: Substrate Binding and Comparison to Ribonucleotide Reductase
1999 · Yi-Shan Yang, John A. Broadwater, et al. · Journal of the American Chemical Society · 58
Expression, purification, and physical characterization of Escherichia coli lipoyl(octanoyl)transferase
2004 · Natasha M. Nesbitt, Camelia Baleanu-Gogonea, et al. · Protein Expression and Purification · 39
VHH antibody targeting the chemokine receptor CX3CR1 inhibits progression of atherosclerosis
2020 · Sarah Low, Haixia Wu, et al. · mAbs · 38
The fundamental, versatile role of diiron enzymes in lipid metabolism
1998 · John A. Broadwater, Jeffrey A. Haas, et al. · Fette Seifen Anstrichmittel · 37
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Synthesis, SAR, and Series Evolution of Novel Oxadiazole-Containing 5-Lipoxygenase Activating Protein Inhibitors: Discovery of 2-[4-(3-{(R)-1-[4-(2-Amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]-N,N-dimethyl-acetamide (BI 665915)
2015 · Hidenori Takahashi, Doris Riether, et al. · Journal of Medicinal Chemistry · 36
Combined PET/DCE-MRI in a Rabbit Model of Atherosclerosis
2018 · Claudia Calcagno, Olivier Lairez, et al. · JACC. Cardiovascular imaging · 33
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EXAFS and Mössbauer characterization of the Diiron(III) site in stearoyl-acyl carrier protein Δ9– desaturase
1998 · Lijin Shu, John A. Broadwater, et al. · JBIC Journal of Biological Inorganic Chemistry · 27
Spinach Holo-Acyl Carrier Protein: Overproduction and Phosphopantetheinylation inEscherichia coliBL21(DE3),in VitroAcylation, and Enzymatic Desaturation of Histidine-Tagged Isoform I
1999 · John A. Broadwater, Brian G. Fox · Protein Expression and Purification · 26
Anti Human CX3CR1 VHH Molecule Attenuates Venous Neointimal Hyperplasia of Arteriovenous Fistula in Mouse Model
2021 · Sanjay Misra, Sreenivasulu Kilari, et al. · Journal of the American Society of Nephrology · 22
Chemical Derivatization Enables MALDI-TOF-Based High-Throughput Screening for Microbial Trimethylamine (TMA)-Lyase Inhibitors
2019 · Martin Winter, Tom Bretschneider, et al. · SLAS DISCOVERY · 19
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Azide adducts of stearoyl-ACP desaturase: a model for μ-1,2 bridging by dioxygen in the binuclear iron active site
1997 · Jingyuan Ai, John A. Broadwater, et al. · JBIC Journal of Biological Inorganic Chemistry · 18
Desaturation of trans-octadecenoyl-acyl carrier protein by stearoyl-acyl carrier protein Δ9 desaturase
2000 · John A. Broadwater, Bryan J. Laundre, et al. · Journal of Inorganic Biochemistry · 15
Discovery and optimization of oxadiazole-based FLAP inhibitors
2017 · Alessandra Bartolozzi, Asitha Abeywardane, et al. · Bioorganic & Medicinal Chemistry Letters · 5
CCDC 1032443: Experimental Crystal Structure Determination
2015 · Takahashi, Hidenori, Riether, Doris, et al. · The Cambridge Structural Database
Works count: 21
Citation count: 1,159
H-index: 16
I10-index: 17
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