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Tomáš Gucký

How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases?
2018 · Radek Jorda, Denisa Hendrychová, et al. · Journal of Medicinal Chemistry · 94
Preparation and Standardisation of Smoke-Water for Seed Germination and Plant Growth Stimulation
2019 · Shubhpriya Gupta, Jakub Hrdlička, et al. · Journal of Plant Growth Regulation · 56
A Novel Series of Highly Potent 2,6,9-Trisubstituted Purine Cyclin-Dependent Kinase Inhibitors
2013 · Tomáš Gucký, Radek Jorda, et al. · Journal of Medicinal Chemistry · 50
Cyclocondensation reaction of heterocyclic carbonyl compounds, Part XIII: Synthesis and cytotoxic activity of some 3,7-diaryl-5-(3,4,5-trimethoxyphenyl)pyrazolo[4,3-e][1,2,4]triazines
2008 · Tomáš Gucký, Iveta Fryšová, et al. · European Journal of Medicinal Chemistry · 45
Discovery of N2-(4-Amino-cyclohexyl)-9-cyclopentyl-N6-(4-morpholin-4-ylmethyl-phenyl)-9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations
2018 · Tomáš Gucký, Eva Řezníčková, et al. · Journal of Medicinal Chemistry · 43
Synthesis and in vitro biological evaluation of 2,6,9-trisubstituted purines targeting multiple cyclin-dependent kinases
2012 · Marek Zatloukal, Radek Jorda, et al. · European Journal of Medicinal Chemistry · 42
Synthesis and kinase inhibitory activity of new sulfonamide derivatives of pyrazolo[4,3-e][1,2,4]triazines
2014 · Mariusz Mojzych, Veronika Šubertová, et al. · European Journal of Medicinal Chemistry · 36
Quantification of karrikins in smoke water using ultra-high performance liquid chromatography–tandem mass spectrometry
2019 · Jakub Hrdlička, Tomáš Gucký, et al. · Plant Methods · 30
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Novel Inhibitors of Cyclin-Dependent Kinases Combat Hepatocellular Carcinoma without Inducing Chemoresistance
2013 · Christine Haider, Markus Grubinger, et al. · Molecular Cancer Therapeutics · 29
Trisubstituted Pyrazolopyrimidines as Novel Angiogenesis Inhibitors
2013 · Sabine B. Weitensteiner, Johanna Liebl, et al. · PLoS ONE · 26
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Synthesis and anticancer activity of some 1,5-diaryl-3-(3,4,5-trihydroxyphenyl)-1H-pyrazolo[4,3-e][1,2,4]triazines
2010 · Tomáš Gucký, Eva Řezníčková, et al. · Monatshefte für Chemie - Chemical Monthly · 23
Intralaboratory comparison of analytical methods for quantification of major phytocannabinoids
2019 · Tibor Béres, Lucie Černochová, et al. · Analytical and Bioanalytical Chemistry · 22
Solid-Phase Synthesis of Trisubstituted Benzo[1,4]-Diazepin-5-one Derivatives
2012 · Veronika Fülöpová, Tomáš Gucký, et al. · ACS Combinatorial Science · 21
Characterization of a Pyrazolo[4,3‐d]pyrimidine Inhibitor of Cyclin‐Dependent Kinases 2 and 5 and Aurora A With Pro‐Apoptotic and Anti‐Angiogenic Activity In Vitro
2015 · Eva Řezníčková, Sabine Weitensteiner, et al. · Chemical Biology & Drug Design · 19
Inhibition of FLT3-ITD Kinase in Acute Myeloid Leukemia by New Imidazo[1,2-b]pyridazine Derivatives Identified by Scaffold Hopping
2023 · Petra Břehová, Eva Řezníčková, et al. · Journal of Medicinal Chemistry · 16
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Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure
2021 · Josef Jansa, Radek Jorda, et al. · European Journal of Medicinal Chemistry · 16
Preparation, characterization and biological activity of C8-substituted cytokinins
2016 · Lenka Zahajská, Jaroslav Nisler, et al. · Phytochemistry · 13
2,6,9-Trisubstituted purines as CRK3 kinase inhibitors with antileishmanial activity in vitro
2015 · Eva Řezníčková, Alexandr Popa, et al. · Bioorganic & Medicinal Chemistry Letters · 12
Activity of 2,6,9-trisubstituted purines as potent PDGFRα kinase inhibitors with antileukaemic activity
2019 · Eva Řezníčková, Tomáš Gucký, et al. · European Journal of Medicinal Chemistry · 11
Trisubstituted purine inhibitors of PDGFRα and their antileukemic activity in the human eosinophilic cell line EOL-1
2017 · Veronika Malínková, Eva Řezníčková, et al. · Bioorganic & Medicinal Chemistry · 10
6-Substituted purines as ROCK inhibitors with anti-metastatic activity
2019 · Jiří Voller, Lenka Zahajská, et al. · Bioorganic Chemistry · 9
Polycyclic heterocycles with acidic N-H group VI. The synthesis of some polycyclic heterocyclic compounds related to 3-phenyl-1,2-dihydro-quinoxaline-2-one
2005 · Iveta Fryšová, Jan Slouka, et al. · ARKIVOC · 8
Cyclisation reactions of hydrazones XXXII. Synthesis of some pyrazolylhydrazones and study of their cyclisation
2011 · Petr Cankař, Michal Maloň, et al. · Monatshefte für Chemie - Chemical Monthly · 7
Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors
2022 · Kristýna Vlková, Tomáš Gucký, et al. · Bioorganic & Medicinal Chemistry Letters · 6
A Stepwise Approach for the Synthesis of Folic Acid Conjugates with Protein Kinase Inhibitors
2017 · Soňa Krajčovičová, Tomáš Gucký, et al. · The Journal of Organic Chemistry · 6
Works count: 59
Citation count: 682
H-index: 16
I10-index: 20
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