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Mia M. Rushe

Affinity enhancement of an in vivo matured therapeutic antibody using structure‐based computational design
2006 · Louis A. Clark, P. Ann Boriack‐Sjodin, et al. · Protein Science · 173
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Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site
2008 · Mia Rushe, Laura Silvian, et al. · Structure · 130
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Antibody Therapy Targeting RAN Proteins Rescues C9 ALS/FTD Phenotypes in C9orf72 Mouse Model
2019 · Lien Nguyen, Fabio Montrasio, et al. · Neuron · 105
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Determinants of the Peptide-induced Conformational Change in the Human Class II Major Histocompatibility Complex Protein HLA-DR1
2000 · Aaron K. Sato, Jennifer A. Zarutskie, et al. · Journal of Biological Chemistry · 85
A Conformational Change in the Human Major Histocompatibility Complex Protein HLA-DR1 Induced by Peptide Binding
1999 · Jennifer A. Zarutskie, Aaron K. Sato, et al. · Biochemistry · 81
Soluble peptide–MHC monomers cause activation of CD8 + T cells through transfer of the peptide to T cell MHC molecules
2002 · Qing Ge, Jennifer D. Stone, et al. · Proceedings of the National Academy of Sciences · 73
The kinetic basis of peptide exchange catalysis by HLA-DM
2001 · Jennifer A. Zarutskie, Robert Busch, et al. · Proceedings of the National Academy of Sciences · 70
Monoclonal Antibodies Specific for the Empty Conformation of HLA-DR1 Reveal Aspects of the Conformational Change Associated with Peptide Binding
2004 · Gregory J. Carven, Sriram Chitta, et al. · Journal of Biological Chemistry · 52
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Artemin Crystal Structure Reveals Insights into Heparan Sulfate Binding
2006 · Laura Silvian, Ping Jin, et al. · Biochemistry · 50
Production of poly(GA) in C9ORF72 patient motor neurons derived from induced pluripotent stem cells
2019 · Sandra Almeida, Gopinath Krishnan, et al. · Acta Neuropathologica · 31
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Structure activity relationships of monocyte chemoattractant proteins in complex with a blocking antibody
2006 · Carl Reid, Mia Rushe, et al. · Protein Engineering Design and Selection · 31
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Functional activity of anti-LINGO-1 antibody opicinumab requires target engagement at a secondary binding site
2020 · Karl J. M. Hanf, Joseph W. Arndt, et al. · mAbs · 24
Germinal‐center kinase‐like kinase co‐crystal structure reveals a swapped activation loop and C‐terminal extension
2016 · Douglas Marcotte, Mia Rushe, et al. · Protein Science · 24
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Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease
2022 · Melanie Jambeau, Kevin D. Meyer, et al. · Proceedings of the National Academy of Sciences · 12
Investigating small molecules to inhibit germinal center kinase-like kinase (GLK/MAP4K3) upstream of PKCθ phosphorylation: Potential therapy to modulate T cell dependent immunity
2018 · Tricia L. May-Dracka, Robert Arduini, et al. · Bioorganic & Medicinal Chemistry Letters · 5
Engineering potent long-acting variants of the Wnt inhibitor DKK2
2017 · Richelle Sopko, Joshua W. Mugford, et al. · Protein Engineering Design and Selection · 4
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Crystal structure of human MCP-1 bound to a blocking antibody, 11K2
2005 · P.A. Boriack-Sjodin, M. Rushe, et al. · Worldwide Protein Data Bank
Works count: 17
Citation count: 950
H-index: 13
I10-index: 14
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