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Author

Chun Xia

Observed name: Xia, Chun
ORCID: 0000-0001-8585-9313
Observed ORCID: 0000-0001-8585-9313
OpenAlex ID: A5087064767
Berberine ameliorates cartilage degeneration in interleukin‐1β‐stimulated rat chondrocytes and in a rat model of osteoarthritis via Akt signalling
2013 · Honghai Zhao, Tongen Zhang, et al. · Journal of Cellular and Molecular Medicine · 88
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17β-Estradiol promotes cell proliferation in rat osteoarthritis model chondrocytes via PI3K/Akt pathway
2011 · Jia Huang, Chun Xia, et al. · Cellular & Molecular Biology Letters · 86
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IL-1β receptor antagonist (IL-1Ra) combined with autophagy inducer (TAT-Beclin1) is an effective alternative for attenuating extracellular matrix degradation in rat and human osteoarthritis chondrocytes
2019 · Fen Wang, Jijie Liu, et al. · Arthritis Research & Therapy · 56
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Overexpression of microRNA-634 suppresses survival and matrix synthesis of human osteoarthritis chondrocytes by targeting PIK3R1
2016 · Xu Cui, Shaojie Wang, et al. · Scientific Reports · 54
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Intra-articular Injection of Kartogenin-Incorporated Thermogel Enhancing Osteoarthritis Treatment
2019 · Shao-Jie Wang, Ji-Zheng Qin, et al. · Frontiers in Chemistry · 35
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Protein kinase B and extracellular signal‐regulated kinase contribute to the chondroprotective effect of morroniside on osteoarthritis chondrocytes
2015 · Liang Cheng, Guoqing Zeng, et al. · Journal of Cellular and Molecular Medicine · 35
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Requirement of the phosphatidylinositol 3-kinase/Akt signaling pathway for the effect of nicotine on interleukin-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis
2012 · Xinpeng Zheng, Chun Xia, et al. · Biochemical and Biophysical Research Communications · 34
microRNAs regulate nitric oxide release from endothelial cells by targeting NOS3
2018 · Ji-zheng Qin, Shao-jie Wang, et al. · Journal of Thrombosis and Thrombolysis · 32
Chondroprotection of PPARα activation by WY14643 via autophagy involving Akt and ERK in LPS‐treated mouse chondrocytes and osteoarthritis model
2019 · Yang Zhou, Xiaolei Chen, et al. · Journal of Cellular and Molecular Medicine · 31
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DAG/PKCδ and IP3/Ca2+/CaMK IIβ Operate in Parallel to Each Other in PLCγ1-Driven Cell Proliferation and Migration of Human Gastric Adenocarcinoma Cells, through Akt/mTOR/S6 Pathway
2015 · Lianzhi Dai, Luhua Zhuang, et al. · International Journal of Molecular Sciences · 29
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Disruption of Phosphoinositide-Specific Phospholipases Cγ1 Contributes to Extracellular Matrix Synthesis of Human Osteoarthritis Chondrocytes
2014 · Guoqing Zeng, Xu Cui, et al. · International Journal of Molecular Sciences · 29
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Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells
2017 · Lianzhi Dai, Xiaolei Chen, et al. · Scientific Reports · 25
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The Involvement of Mutual Inhibition of ERK and mTOR in PLCγ1-Mediated MMP-13 Expression in Human Osteoarthritis Chondrocytes
2015 · Zejun Liu, Heguo Cai, et al. · International Journal of Molecular Sciences · 23
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PLCγ1 inhibition‐driven autophagy of IL‐1β‐treated chondrocyte confers cartilage protection against osteoarthritis, involving AMPK, Erk and Akt
2020 · Xiaolei Chen, Yue Wang, et al. · Journal of Cellular and Molecular Medicine · 22
Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Cα in chondrocytes
2012 · Qingzhi Chen, Bing Zhang, et al. · Folia Histochemica et Cytobiologica · 22
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Phosphoinositide specific phospholipase Cγ1 inhibition-driven autophagy caused cell death in human lung adenocarcinoma A549 cells in vivo and in vitro
2020 · Xiaohong Lu, Haijing Fu, et al. · International Journal of Biological Sciences · 17
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Conversion Hip Arthroplasty Using Standard and Long Stems after Failed Internal Fixation of Intertrochanteric Fractures
2022 · Tengbin Shi, Xinyu Fang, et al. · Orthopaedic Surgery · 16
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Suppressing phosphoinositide-specific phospholipases Cγ1 promotes mineralization of osteoarthritic subchondral bone osteoblasts via increasing autophagy, thereby ameliorating articular cartilage degeneration
2021 · Yue Wang, Tongen Zhang, et al. · Bone · 16
Reticulocalbin 1 is required for proliferation and migration of non‐small cell lung cancer cells regulated by osteoblast‐conditioned medium
2021 · Haijing Fu, Rui Chen, et al. · Journal of Cellular and Molecular Medicine · 16
Lentivirus-mediated PLCγ1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma
2016 · Bingchang Zhang, Fen Wang, et al. · Oncotarget · 14
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Suppressing PLCγ1 enhances osteogenic and chondrogenic potential of BMSCs
2020 · Xiaolei Chen, Yue Wang, et al. · Biochemical and Biophysical Research Communications · 11
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Metastasis of human gastric adenocarcinoma partly depends on phosphoinositide-specific phospholipase γ1 expression
2014 · Luhua Zhuang, Bingchang Zhang, et al. · Folia Histochemica et Cytobiologica · 11
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PLCγ1 inhibition combined with inhibition of apoptosis and necroptosis increases cartilage matrix synthesis in IL‐1β‐treated rat chondrocytes
2020 · Xiaolei Chen, Ri Chen, et al. · FEBS Open Bio · 9
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Different roles of Akt and mechanistic target of rapamycin in serum‑dependent chondroprotection of human osteoarthritic chondrocytes
2017 · Tongen Zhang, Jijie Liu, et al. · International Journal of Molecular Medicine · 9
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12-O-tetradecanoylphorbol-1, 3-acetate induces the negative regulation of protein kinase B by protein kinase Cα during gastric cancer cell apoptosis
2010 · Bing Zhang, Chun Xia · Cellular & Molecular Biology Letters · 9
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Works count: 57
Citation count: 778
H-index: 16
I10-index: 22
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