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Céline Cottereaux

Observed names: C Cottereaux, C. Cottereaux, Celine Cottereaux, Céline Cottereaux
Institution: Galapagos (France)
ORCID: 0000-0002-4883-3154
Observed ORCID: 0000-0002-4883-3154
OpenAlex ID: A5087093764
Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2- a ]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis
2017 · Nicolas Desroy, Christopher Housseman, et al. · Journal of Medicinal Chemistry · 148
Discovery of GLPG1972/S201086, a Potent, Selective, and Orally Bioavailable ADAMTS-5 Inhibitor for the Treatment of Osteoarthritis
2021 · Franck Brebion, Romain Gosmini, et al. · Journal of Medicinal Chemistry · 67
Discovery of 9-Cyclopropylethynyl-2-(( S )-1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1- a ]isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing Evaluation in a Phase II Clinical Trial
2020 · Frédéric Labéguère, Sonia Dupont, et al. · Journal of Medicinal Chemistry · 53
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IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases
2023 · Stéphanie Lavazais, Manja Jargosch, et al. · Science Translational Medicine · 51
Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5
2021 · P. Clement-Lacroix, C.B. Little, et al. · Osteoarthritis and Cartilage · 30
Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization
2014 · Roland Blanqué, Liên Lepescheux, et al. · BMC Musculoskeletal Disorders · 26
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GLPG1972: a potent, selective, orally available adamts-5 inhibitor for the treatment of OA
2017 · P. Clement-Lacroix, C. Little, et al. · Osteoarthritis and Cartilage · 17
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Mechanisms involved in prostaglandin-induced increase in bone resorption in neonatal mouse calvaria
2001 · C.R. Gardner, R. Blanqué, et al. · Prostaglandins Leukotrienes and Essential Fatty Acids · 16
Increases in osteocalcin after ovariectomy are amplified by LPS injection: Strain differences in bone remodelling
1998 · R. Blanqué, C. Cottereaux, et al. · General Pharmacology The Vascular System · 10
Effects of SK&F 86002 on cytokine-stimulated IL6 production in cultured neonatal mouse calvaria and SaOS2 osteoblastic cells: the role of prostaglandins and other mechanisms of action.
1997 · R Blanque, C Cottereaux, et al. · PubMed · 9
ADAMTS-5 inhibition with the potent and highly selective inhibitor GLPG1972 results in strong disease-modifying OA drug effects in the rat meniscectomy model
2018 · P. Clement-Lacroix, S. Meurisse, et al. · Osteoarthritis and Cartilage · 7
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Design of a potent and selective dual JAK1/TYK2 inhibitor
2024 · Oscar Mammoliti, Christel Menet, et al. · Bioorganic & Medicinal Chemistry · 5
Pharmacological profile and efficacy of GLPG1690, a novel ATX inhibitor for COPD treatment
2015 · Roland Blanque, Nicolas Desroy, et al. · European Respiratory Journal · 5
OP0258 Efficacy of the highly selective adamts-5 inhibitor glpg1972 in the rat meniscectomy model
2018 · L. Lepescheux, P. Clement-Lacroix, et al. · Annals of the Rheumatic Diseases · 4
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OP0180 Pharmacological characterization of the ADAMTS-5 inhibitor GLPG1972: an oral anti-catabolic agent for the treatment of osteoarthritis
2017 · P Clement-Lacroix, C Little, et al. · Annals of the Rheumatic Diseases · 3
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Phasic production of urinary pyridinium crosslinks in mice: The effect of ovariectomy
2001 · R. Blanqué, C. Cottereaux, et al. · Calcified Tissue International · 3
Ab0144 Pharmacological Characterization of Glpg3667, a Selective Tyk2 Inhibitor, Supports Development in Dermatomyositis and Systemic Lupus Erythematosus
2023 · R. Aggarwal, E.F. Morand, et al. · Annals of the Rheumatic Diseases · 1
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Pharmacological Characterization of GLPG3667, a Tyrosine Kinase 2-Selective Inhibitor, for the Treatment of Inflammatory and Autoimmune Diseases
2026 · Céline Cottereaux, May-Linda Lepage, et al. · Inflammation
Works count: 19
Citation count: 455
H-index: 9
I10-index: 9
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