Author

Allison L. Arnold

Observed names: Allison Arnold, Arnold, Allison L.

Institution: Vanderbilt University

Observed institutions: Vanderbilt University, Vanderbilt University Medical Center

OpenAlex ID: A5087494308

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

2016 · Nicholas F. Pelz, Zhiguo Bian, et al. · Journal of Medicinal Chemistry · 158

Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer

2019 · Taekyu Lee, Plamen P. Christov, et al. · Journal of Medicinal Chemistry · 73

Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design

2018 · Subrata Shaw, Zhiguo Bian, et al. · Journal of Medicinal Chemistry · 66

Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS

2018 · Timothy R. Hodges, Jason R. Abbott, et al. · Journal of Medicinal Chemistry · 62

Discovery and biological characterization of potent myeloid cell leukemia‐1 inhibitors

2016 · Taekyu Lee, Zhiguo Bian, et al. · FEBS Letters · 62

Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods

2020 · Dhruba Sarkar, Edward T. Olejniczak, et al. · Journal of Medicinal Chemistry · 33

Small Molecule SOS1 Agonists Modulate MAPK and PI3K Signaling via Independent Cellular Responses

2019 · Denis T. Akan, Jennifer E. Howes, et al. · ACS Chemical Biology · 22

Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors

2024 · James C. Tarr, James M. Salovich, et al. · Journal of Medicinal Chemistry · 18

Discovery of BI-2493, a Pan-KRAS Inhibitor Showing In Vivo Efficacy

2025 · Joachim Bröker, Alex G. Waterson, et al. · Journal of Medicinal Chemistry · 16

Understanding the Species Selectivity of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors

2018 · Bin Zhao, Allison L. Arnold, et al. · Biochemistry · 14

Discovery of Small Molecules that Bind to Son of Sevenless 2 (SOS2)

2025 · Krzysztof M. Zak, Alex G. Waterson, et al. · Journal of Medicinal Chemistry · 6

Discovery of Macrocyclic Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors that Demonstrate Potent Cellular Efficacy and In Vivo Activity in a Mouse Solid Tumor Xenograft Model

2025 · James C. Tarr, Kyuok Jeon, et al. · Journal of Medicinal Chemistry · 5

Abstract 3727: Small molecule Mcl-1 inhibitors induce apoptosis and death in multiple cancer subtypes in vitro

2016 · John L. Sensintaffar, Allison Arnold, et al. · Cancer Research · 1

CCDC 2023739: Experimental Crystal Structure Determination

2020 · Shaw, Subrata, Bian, Zhiguo, et al. · The Cambridge Structural Database

Abstract 3726: Predicting cellular response to small molecule Mcl-1 antagonists

2016 · Leah Hogdal, John Sensintaffar, et al. · Cancer Research

Abstract 3551: Discovery of orally bioavailable novel Mcl-1 inhibitors that exhibit selective anti-proliferative activity in Mcl-1 sensitive cancer cell lines

2016 · Taekyu Lee, Zhiguo Bian, et al. · Cancer Research

Abstract 4331: Discovery of potent 2-Indole-acylsulfonamide Mcl-1 inhibitors using structure guided fragment-based methods

2016 · Subrata Shaw, James Chris Tarr, et al. · Cancer Research

Works count: 17

Citation count: 536

H-index: 10

I10-index: 10