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Author

Iram Khan

Observed names: I F Khan, Iram F Khan, Iram F. Khan, Khan, Iram
ORCID: 0000-0003-4202-7108
Observed ORCID: 0000-0003-4202-7108
OpenAlex ID: A5087723134
Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template
2015 · Blythe D. Sather, Guillermo S. Romano Ibarra, et al. · Science Translational Medicine · 232
AAV-mediated gene targeting methods for human cells
2011 · Iram F Khan, Roli K Hirata, et al. · Nature Protocols · 189
Successful treatment of canine leukocyte adhesion deficiency by foamy virus vectors
2007 · Thomas R Bauer, James M Allen, et al. · Nature Medicine · 155
Engineering Protein-Secreting Plasma Cells by Homology-Directed Repair in Primary Human B Cells
2017 · King L. Hung, Iana Meitlis, et al. · Molecular Therapy · 143
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Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome
2016 · Nicholas Hubbard, David Hagin, et al. · Blood · 142
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Gene editing to induce FOXP3 expression in human CD4 + T cells leads to a stable regulatory phenotype and function
2020 · Yuchi Honaker, Nicholas Hubbard, et al. · Science Translational Medicine · 127
Engineering of Human Pluripotent Stem Cells by AAV-mediated Gene Targeting
2010 · Iram F Khan, Roli K Hirata, et al. · Molecular Therapy · 114
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Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells
2014 · Cathy X. Wang, Blythe D. Sather, et al. · Blood · 93
Pancreatic islet-specific engineered T regs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models
2022 · Soo Jung Yang, Akhilesh K. Singh, et al. · Science Translational Medicine · 88
Normal Collagen and Bone Production by Gene-targeted Human Osteogenesis Imperfecta iPSCs
2011 · David R Deyle, Iram F Khan, et al. · Molecular Therapy · 88
Intraosseous Delivery of Lentiviral Vectors Targeting Factor VIII Expression in Platelets Corrects Murine Hemophilia A
2015 · Xuefeng Wang, Simon C Shin, et al. · Molecular Therapy · 81
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Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks
2013 · Ryan Kuhar, Kamila S. Gwiazda, et al. · Nucleic Acids Research · 68
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Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo
2022 · Rene Yu-Hong Cheng, King L. Hung, et al. · Nature Communications · 53
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High Efficiency CRISPR/Cas9-mediated Gene Editing in Primary Human T-cells Using Mutant Adenoviral E4orf6/E1b55k “Helper” Proteins
2016 · Kamila S Gwiazda, Alexandra E Grier, et al. · Molecular Therapy · 35
Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector
2021 · Brenda J. Seymour, Swati Singh, et al. · Molecular Therapy — Methods & Clinical Development · 19
Lack of genotoxicity due to foamy virus vector integration in human iPSCs
2013 · D R Deyle, I F Khan, et al. · Gene Therapy · 15
Generation of a cost-effective cell line for support of high-throughput isolation of primary human B cells and monoclonal neutralizing antibodies
2020 · Rachael E. Whaley, Sarah Ameny, et al. · Journal of Immunological Methods · 14
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Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector
2016 · Swati Singh, Iram Khan, et al. · Molecular Therapy — Methods & Clinical Development · 14
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DNA-PK inhibition enhances gene editing efficiency in HSPCs for CRISPR-based treatment of X-linked hyper IgM syndrome
2024 · Cole M. Pugliano, Mason Berger, et al. · Molecular Therapy — Methods & Clinical Development · 13
A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin
2023 · Eirini Vamva, Stosh Ozog, et al. · Molecular Therapy — Methods & Clinical Development · 13
Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus
2014 · Yupeng Wang, Iram F. Khan, et al. · Nucleic Acids Research · 9
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Efficient and sustained FOXP3 locus editing in hematopoietic stem cells as a therapeutic approach for IPEX syndrome
2023 · Swati Singh, Cole M. Pugliano, et al. · Molecular Therapy — Methods & Clinical Development · 7
132. Targeting the BTK Locus in Primary Human Hematopoietic Cells with TALENs and AAV Donor Template
2016 · Courtnee Clough, Yupeng Wang, et al. · Molecular Therapy · 6
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Preclinical efficacy and safety assessment of engineered regulatory T cells for treatment of IPEX and other autoimmune disorders
2026 · Yuchi Honaker, Noelle P. Dahl, et al. · Molecular Therapy · 4
Targeting human plasma cells using regulated BCMA CAR T cells eliminates circulating antibodies in humanized mice
2024 · Yuchi Honaker, David Gruber, et al. · Molecular Therapy · 3
Works count: 42
Citation count: 1,732
H-index: 15
I10-index: 20
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