Get started
Author

László Csanády

Observed names: Csanady Laszlo, Csanady, L, Csanady, Laszlo, Csanády László, Csanády, László, L. Csanady, Laszlo Csanady, László Csanády
ORCID: 0000-0002-6547-5889
Observed ORCID: 0000-0002-6547-5889
OpenAlex ID: A5088037931
The ABC protein turned chloride channel whose failure causes cystic fibrosis
2006 · David C. Gadsby, Paola Vergani, et al. · Nature · 704
Molecular Structure of the Human CFTR Ion Channel
2017 · Fangyu Liu, Zhe Zhang, et al. · Cell · 525
PDF
Structure, Gating, and Regulation of the CFTR Anion Channel
2018 · László Csanády, Paola Vergani, et al. · Physiological Reviews · 246
Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation
2018 · Zhe Zhang, Balázs Tóth, et al. · eLife · 143
Severed Channels Probe Regulation of Gating of Cystic Fibrosis Transmembrane Conductance Regulator by Its Cytoplasmic Domains
2000 · László Csanády, Kim W. Chan, et al. · The Journal of General Physiology · 127
Strict coupling between CFTR’s catalytic cycle and gating of its Cl − ion pore revealed by distributions of open channel burst durations
2009 · László Csanády, Paola Vergani, et al. · Proceedings of the National Academy of Sciences · 115
Four Ca2+ Ions Activate TRPM2 Channels by Binding in Deep Crevices near the Pore but Intracellularly of the Gate
2009 · László Csanády, Beáta Törőcsik · The Journal of General Physiology · 102
PDF
A Novel Kinetic Assay of Mitochondrial ATP-ADP Exchange Rate Mediated by the ANT
2009 · Christos Chinopoulos, Szilvia Vajda, et al. · Biophysical Journal · 100
PDF
Identification of Direct and Indirect Effectors of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel
2010 · Balázs Tóth, László Csanády · Journal of Biological Chemistry · 99
Severed Molecules Functionally Define the Boundaries of the Cystic Fibrosis Transmembrane Conductance Regulator's Nh2-Terminal Nucleotide Binding Domain
2000 · Kim W. Chan, László Csanády, et al. · The Journal of General Physiology · 77
Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents
2012 · Balázs Tóth, László Csanády · Proceedings of the National Academy of Sciences · 71
Preferential Phosphorylation of R-domain Serine 768 Dampens Activation of CFTR Channels by PKA
2005 · László Csanády, Donna Seto-Young, et al. · The Journal of General Physiology · 71
PDF
Rapid Kinetic Analysis of Multichannel Records by a Simultaneous Fit to All Dwell-Time Histograms
2000 · László Csanády · Biophysical Journal · 71
PDF
Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2′-phosphate
2015 · Balázs Tóth, Iordan Iordanov, et al. · The Journal of General Physiology · 67
PDF
Timing of CFTR Pore Opening and Structure of Its Transition State
2015 · Ben Sorum, Dávid Czégé, et al. · Cell · 65
PDF
Thermodynamics of CFTR Channel Gating: A Spreading Conformational Change Initiates an Irreversible Gating Cycle
2006 · László Csanády, Angus C. Nairn, et al. · The Journal of General Physiology · 59
The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity
2016 · Iordan Iordanov, Csaba Mihályi, et al. · eLife · 55
Functional Roles of Nonconserved Structural Segments in CFTR's NH2-terminal Nucleotide Binding Domain
2004 · László Csanády, Kim W. Chan, et al. · The Journal of General Physiology · 54
A single active catalytic site is sufficient to promote transport in P-glycoprotein
2016 · Orsolya Bársony, Gábor Szalóki, et al. · Scientific Reports · 47
PDF
Mutant cycles at CFTR’s non-canonical ATP-binding site support little interface separation during gating
2011 · Andras Szollosi, Daniella R. Muallem, et al. · The Journal of General Physiology · 41
Simple binding of protein kinase A prior to phosphorylation allows CFTR anion channels to be opened by nucleotides
2020 · Csaba Mihályi, Iordan Iordanov, et al. · Proceedings of the National Academy of Sciences · 40
Cystic fibrosis drug ivacaftor stimulates CFTR channels at picomolar concentrations
2019 · László Csanády, Beáta Töröcsik · eLife · 40
PDF
Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating
2014 · Balázs Tóth, Iordan Iordanov, et al. · Proceedings of the National Academy of Sciences · 40
PDF
Mitoxantrone is expelled by the ABCG2 multidrug transporter directly from the plasma membrane
2010 · László Homolya, Tamás I. Orbán, et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 40
PDF
Ion channels as targets to treat cystic fibrosis lung disease
2017 · S. Lorraine Martin, Vinciane Saint-Criq, et al. · Journal of Cystic Fibrosis · 37
PDF
Works count: 133
Citation count: 3,527
H-index: 28
I10-index: 42
Year
Topic
Type