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Tríona Ní Chonghaile

Observed names: Chonghaile, Triona Ní, T N Chonghaile, T Ni Chonghaile, T Ní Chonghaile, T ni Chonghaile, T. Ni Chonghaile, T. Ní Chonghaile, T.N. Chonghaile, Triona Chonghaile, Triona Ni Chonghaile, Triona Ní Chonghaile, Triona ni Chonghaile, Triona Ni Chonghaile, Triona Ní Chonghaile, Tríona Ní Chonghaile*, Tríona Ní Chonghaíle
Observed institutions: University College Dublin, Harvard University, Royal College of Surgeons in Ireland, Lund University, Ollscoil na Gaillimhe – University of Galway, Trinity College Dublin, University of Cambridge, The Netherlands Cancer Institute, OncoMark (Ireland), St. Vincent's University Hospital, Dana-Farber Cancer Institute, Skåne University Hospital, Institut Curie
ORCID: 0000-0002-3041-4031
Observed ORCID: 0000-0002-3041-4031
OpenAlex ID: A5088286862
Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy
2011 · Triona Ni Chonghaile, Kristopher A. Sarosiek, et al. · Science · 610
Maturation Stage of T-cell Acute Lymphoblastic Leukemia Determines BCL-2 versus BCL-XL Dependence and Sensitivity to ABT-199
2014 · Triona Ni Chonghaile, Justine E. Roderick, et al. · Cancer Discovery · 289
Mimicking the BH3 domain to kill cancer cells
2008 · T Ni Chonghaile, A Letai · Oncogene · 276
Bcl-2 family on guard at the ER
2009 · Eva Szegezdi, David C. MacDonald, et al. · American Journal of Physiology-Cell Physiology · 245
Mitochondria: gatekeepers of response to chemotherapy
2013 · Kristopher A. Sarosiek, Triona Ni Chonghaile, et al. · Trends in Cell Biology · 177
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MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199
2015 · Juliana M. Benito, Laura Godfrey, et al. · Cell Reports · 163
BH3 profiling identifies heterogeneous dependency on Bcl-2 family members in multiple myeloma and predicts sensitivity to BH3 mimetics
2015 · C Touzeau, J Ryan, et al. · Leukemia · 162
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment
2011 · Abdel Kareem Azab, Phong Quang, et al. · Blood · 126
Therapeutic Rationale to Target Highly Expressed CDK7 Conferring Poor Outcomes in Triple-Negative Breast Cancer
2017 · Bo Li, Triona Ni Chonghaile, et al. · Cancer Research · 98
Targeting the miR-221–222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma
2015 · Jian-Jun Zhao, Zhang-Bo Chu, et al. · Cancer Research · 95
Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl‐xL
2007 · Janice LV Reeve, Eva Szegezdi, et al. · Journal of Cellular and Molecular Medicine · 91
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Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 against Pediatric Acute Lymphoblastic Leukemia Xenografts
2014 · Santi Suryani, Hernan Carol, et al. · Clinical Cancer Research · 88
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Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer
2021 · Catríona M. Dowling, Kate E. R. Hollinshead, et al. · Science Advances · 78
PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia
2018 · Ingrid M. Ariës, Kimberly Bodaar, et al. · The Journal of Experimental Medicine · 59
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The Emerging Role of Non-traditional Ubiquitination in Oncogenic Pathways
2017 · Lisa Dwane, William M. Gallagher, et al. · Journal of Biological Chemistry · 49
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The path to venetoclax resistance is paved with mutations, metabolism, and more
2022 · Graeme P. Sullivan, Lyndsey Flanagan, et al. · Science Translational Medicine · 47
A Functional Genomic Screen Identifies the Deubiquitinase USP11 as a Novel Transcriptional Regulator of ERα in Breast Cancer
2020 · Lisa Dwane, Aisling E. O'Connor, et al. · Cancer Research · 40
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Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL
2006 · Tríona Ní Chonghaile, Caoimhín G. Concannon, et al. · APOPTOSIS · 32
Shining a light on metabolic vulnerabilities in non-small cell lung cancer
2020 · Catríona M. Dowling, Hua Zhang, et al. · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 29
Advances in the Design and Development of PROTAC-mediated HDAC Degradation
2021 · Daniel Alencar Rodrigues, Andrew Roe, et al. · Current Topics in Medicinal Chemistry · 27
JAK3 mutations and mitochondrial apoptosis resistance in T-cell acute lymphoblastic leukemia
2022 · Kimberly Bodaar, Natsuko Yamagata, et al. · Leukemia · 26
The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia
2019 · Sean Quinlan, Paula Merino-Serrais, et al. · Frontiers in Immunology · 24
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The spleen as a sanctuary site for residual leukemic cells following ABT-199 monotherapy in ETP-ALL
2021 · Alessandra Di Grande, Sofie Peirs, et al. · Blood Advances · 22
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BCL-2 modulates the unfolded protein response by enhancing splicing of X-box binding protein-1
2015 · Triona Ni Chonghaile, Sanjeev Gupta, et al. · Biochemical and Biophysical Research Communications · 22
Secondary plasma cell leukaemia treated with single agent venetoclax
2020 · Siobhan V. Glavey, Lyndsey Flanagan, et al. · British Journal of Haematology · 21
Works count: 156
Citation count: 3,048
H-index: 22
I10-index: 31
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