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Jessica P. Alexander

Conversion of Acetaminophen to the Bioactive N-Acylphenolamine AM404 via Fatty Acid Amide Hydrolase-dependent Arachidonic Acid Conjugation in the Nervous System
2005 · Edward D. Högestätt, Bo A.G. Jönsson, et al. · Journal of Biological Chemistry · 454
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The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
2010 · William R Marrs, Jacqueline L Blankman, et al. · Nature Neuroscience · 442
Mechanism of Carbamate Inactivation of FAAH: Implications for the Design of Covalent Inhibitors and In Vivo Functional Probes for Enzymes
2005 · Jessica P. Alexander, Benjamin F. Cravatt · Chemistry & Biology · 226
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Novel Mechanistic Class of Fatty Acid Amide Hydrolase Inhibitors with Remarkable Selectivity
2007 · Kyunghye Ahn, Douglas S. Johnson, et al. · Biochemistry · 217
Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders
2018 · Justin S. Cisar, Olivia D. Weber, et al. · Journal of Medicinal Chemistry · 161
The Putative Endocannabinoid Transport Blocker LY2183240 Is a Potent Inhibitor of FAAH and Several Other Brain Serine Hydrolases
2006 · Jessica P. Alexander, Benjamin F. Cravatt · Journal of the American Chemical Society · 140
Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain
2014 · Harry R. Chobanian, Yan Guo, et al. · ACS Medicinal Chemistry Letters · 41
Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase
2013 · Ping Liu, Terence G. Hamill, et al. · ACS Medicinal Chemistry Letters · 36
Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators
2018 · Jason R. Clapper, Cassandra L. Henry, et al. · Journal of Pharmacology and Experimental Therapeutics · 32
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Inhibition of Spleen Tyrosine Kinase Attenuates Allergen-Mediated Airway Constriction
2013 · Lily Y. Moy, Yanlin Jia, et al. · American Journal of Respiratory Cell and Molecular Biology · 28
γ-Glutamyl Hydrolase: Kinetic Characterization of Isopeptide Hydrolysis Using Fluorogenic Substrates
2008 · Jessica P. Alexander, Thomas J. Ryan, et al. · Biochemistry · 8
Discovery of MK-3168: A clinical PET tracer as a target engagement biomarker for FAAH
2011 · Ping Liu, Terence G. Hamill, et al. · Abstracts of papers - American Chemical Society
Works count: 12
Citation count: 1,785
H-index: 10
I10-index: 10
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