Author

Silvia Pesci

Observed names: Pesci, S., S. PESCI, S. Pesci

Observed institutions: Merck & Co., Inc., Rahway, NJ, USA (United States), University of Salerno, MSD (Italy), Sigma Tau (Italy), IRBM, Sapienza University of Rome

OpenAlex ID: A5088771230

Discovery of 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): A Novel Oral Poly(ADP-ribose)polymerase (PARP) Inhibitor Efficacious in BRCA-1 and -2 Mutant Tumors

2009 · Philip Jones, Sergio Altamura, et al. · Journal of Medicinal Chemistry · 327

Discovery and Synthesis of HIV Integrase Inhibitors: Development of Potent and Orally Bioavailable N-Methyl Pyrimidones

2007 · Cristina Gardelli, Emanuela Nizi, et al. · Journal of Medicinal Chemistry · 67

The monoethyl ester of meconic acid is an active site inhibitor of HCV NS5B RNA-dependent RNA polymerase

2004 · Paola Pace, Emanuela Nizi, et al. · Bioorganic & Medicinal Chemistry Letters · 56

Lanthanides in organic synthesis: Eu+3-catalyzed Michael addition of 1,3- dicarbonyl compounds

1993 · Francesco Bonadies, Alessandra Lattanzi, et al. · Tetrahedron Letters · 50

Allosteric inhibitors of hepatitis C virus NS5B polymerase thumb domain site II: Structure-based design and synthesis of new templates

2010 · Savina Malancona, Monica Donghi, et al. · Bioorganic & Medicinal Chemistry · 31

Synthesis and antiviral properties of novel 7-heterocyclic substituted 7-deaza-adenine nucleoside inhibitors of Hepatitis C NS5B polymerase

2012 · M. Emilia Di Francesco, Salvatore Avolio, et al. · Bioorganic & Medicinal Chemistry · 30

Synthesis of a hexahydropyrimido[1,2-a]azepine-2-carboxamide derivative useful as an HIV integrase inhibitor

2007 · Marco Ferrara, Benedetta Crescenzi, et al. · Tetrahedron Letters · 20

Synthesis of Cycloalkanoindoles by an Unusual DAST‐Triggered Rearrangement Reaction

2004 · Giuseppe Giannini, Mauro Marzi, et al. · European Journal of Organic Chemistry · 20

Novel Macrocyclic Inhibitors of Hepatitis C NS3/4A Protease Featuring a 2-Amino-1,3-thiazole as a P4 Carbamate Replacement

2009 · M. Emilia Di Francesco, Gabriella Dessole, et al. · Journal of Medicinal Chemistry · 19

An easy approach to butenolides by Horner-Wadsworth-Emmons olefination of α-hydroxy ketones

1995 · Francesco Bonadies, Antonella Cardilli, et al. · Tetrahedron Letters · 19

3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates—fast access to a heterocyclic scaffold for HIV-1 integrase inhibitors

2008 · Olaf D. Kinzel, Richard G. Ball, et al. · Tetrahedron Letters · 17

Inhibitors of the Hepatitis C Virus NS3 Protease with Basic Amine Functionality at the P3-Amino Acid N-Terminus: Discovery and Optimization of a New Series of P2−P4 Macrocycles

2009 · Steven Harper, Marco Ferrara, et al. · Journal of Medicinal Chemistry · 16

Chemical, photochemical and enzymatic approach to furylhydroperoxides

1997 · Arrigo Scettri, Francesco Bonadies, et al. · Tetrahedron · 11

Novel P2–P4 macrocyclic inhibitors of HCV NS3/4A protease by P3 succinamide fragment depeptidization strategy

2009 · Marco Pompei, Maria Emilia Di Francesco, et al. · Bioorganic & Medicinal Chemistry Letters · 10

A general approach to homochiral α-amino substituted bromo-heteroaromatics suitable for two-dimensional rapid analogue synthesis

2009 · Carsten Schultz-Fademrecht, Olaf Kinzel, et al. · Tetrahedron · 10

Studies of metabolism and disposition of potent human immunodeficiency virus (HIV) integrase inhibitors using19F-NMR spectroscopy

2007 · E. Monteagudo, S. Pesci, et al. · Xenobiotica · 9

Photo-oxidation of 2-(2-furyl)-1,3-dicarbonyl compounds

1992 · R. Antonioletti, F. Bonadies, et al. · Tetrahedron Letters · 3

Regioselective Synthesis of 7,8-Dihydropyrrolo[1,2-a]pyrimidin-4(6H)-ones and 7,8-Dihydropyrrolo[1,2-a]pyrimidin-2(6H)-ones

2009 · Monica Donghi, Silvia Pesci, et al. · Synlett · 1

ChemInform Abstract: Synthesis of a Hexahydropyrimido[1,2‐a]azepine‐2‐carboxamide Derivative (I) Useful as an HIV Integrase Inhibitor.

2008 · Marco Ferrara, Benedetta Crescenzi, et al. · ChemInform · 1

ChemInform Abstract: An Easy Approach to Butenolides by Horner‐Wadsworth‐Emmons Olefination of α‐Hydroxy Ketones.

1995 · F. BONADIES, A. CARDILLI, et al. · ChemInform · 1

ChemInform Abstract: Regioselective Synthesis of 7,8‐Dihydropyrrolo[1,2‐a]pyrimidin‐4(6H)‐ones and 7,8‐Dihydropyrrolo[1,2‐a]pyrimidin‐2(6H)‐ones.

2010 · Monica Donghi, Silvia Pesci, et al. · ChemInform

ChemInform Abstract: Novel P2‐P4 Macrocyclic Inhibitors of HCV NS3/4A Protease by P3 Succinamide Fragment Depeptidization Strategy.

2010 · Marco Pompei, Maria Emilia Di Francesco, et al. · ChemInform

ChemInform Abstract: 3‐Hydroxy‐4‐oxo‐4H‐pyrido[1,2‐a]pyrimidine‐2‐carboxylates — Fast Access to a Heterocyclic Scaffold for HIV‐1 Integrase Inhibitors.

2009 · Olaf D. Kinzel, Richard G. Ball, et al. · ChemInform

CCDC 692685: Experimental Crystal Structure Determination

2009 · Kinzel, O.D., Ball, R.G., et al. · The Cambridge Structural Database

Synthesis of Cycloalkanoindoles by an Unusual DAST‐Triggered Rearrangement Reaction.

2004 · Giuseppe Giannini, Mauro Marzi, et al. · ChemInform

Works count: 28

Citation count: 718

H-index: 12

I10-index: 15