Product
Help
Pricing
About
Jobs
Log in
Get started
Author
Add to collection
Elizabeth M. Rosethorne
Observed names:
E M Rosethorne,
Elizabeth M Rosethorne,
Elizabeth Rosethorne,
ElizabethM. Rosethorne
Observed institutions:
Novartis (Switzerland),
University of Nottingham,
University of Leicester,
University of Bristol,
Queen's Medical Centre,
Novartis Institutes for BioMedical Research,
University of Bath,
University of Birmingham,
Vrije Universiteit Amsterdam
show all 9
ORCID:
0000-0001-6877-2320
Observed ORCID:
0000-0001-6877-2320
OpenAlex ID:
A5088950438
μ-Opioid Receptors: Correlation of Agonist Efficacy for Signalling with Ability to Activate Internalization
2010
·
Jamie McPherson
, Guadalupe Rivero
, et al.
·
Molecular Pharmacology
·
260
The M 3 -muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner
2010
·
Benoit Poulin
, Adrian Butcher
, et al.
·
Proceedings of the National Academy of Sciences
·
150
Agonist-Biased Signaling at the Histamine H4 Receptor: JNJ7777120 Recruits β-Arrestin without Activating G Proteins
2010
·
Elizabeth M. Rosethorne
, Steven J. Charlton
·
Molecular Pharmacology
·
113
Endomorphin-2: A Biased Agonist at the μ-Opioid Receptor
2012
·
Guadalupe Rivero
, Javier Llorente
, et al.
·
Molecular Pharmacology
·
102
PDF
M 3 -muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1
2010
·
Kok Choi Kong
, Adrian J. Butcher
, et al.
·
Proceedings of the National Academy of Sciences
·
101
Analysis of Multiple Histamine H4 Receptor Compound Classes Uncovers Gαi Protein- and β-Arrestin2-Biased Ligands
2012
·
Saskia Nijmeijer
, Henry F. Vischer
, et al.
·
Molecular Pharmacology
·
52
Biased M1-muscarinic-receptor-mutant mice inform the design of next-generation drugs
2020
·
Sophie J. Bradley
, Colin Molloy
, et al.
·
Nature Chemical Biology
·
48
PDF
Key aspects of modern GPCR drug discovery
2023
·
Phil Addis
, Utsav Bali
, et al.
·
SLAS DISCOVERY
·
44
PDF
Efficacy is a contributing factor to the clinical onset of bronchodilation of inhaled β2-adrenoceptor agonists
2010
·
Elizabeth M. Rosethorne
, Robert J. Turner
, et al.
·
Naunyn-Schmiedeberg s Archives of Pharmacology
·
41
Detailed analysis of biased histamine H 4 receptor signalling by JNJ 7777120 analogues
2013
·
S Nijmeijer
, H F Vischer
, et al.
·
British Journal of Pharmacology
·
40
Inhibition of the Proliferation of Human Lung Fibroblasts by Prostacyclin Receptor Agonists is Linked to a Sustained cAMP Signal in the Nucleus
2021
·
Maxine J. Roberts
, Lauren T. May
, et al.
·
Frontiers in Pharmacology
·
36
PDF
Regulation of cyclic AMP response-element binding-protein (CREB) by Gq/11-protein-coupled receptors in human SH-SY5Y neuroblastoma cells
2007
·
Elizabeth M. Rosethorne
, Stefan R. Nahorski
, et al.
·
Biochemical Pharmacology
·
35
PDF
The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response
2018
·
Maxine J. Roberts
, Rebecca E. Broome
, et al.
·
Respiratory Research
·
33
PDF
An investigation into the structure–activity relationships associated with the systematic modification of the β2-adrenoceptor agonist indacaterol
2012
·
David Beattie
, David Beer
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
33
Airway remodeling disease: primary human structural cells and phenotypic and pathway assays to identify targets with potential to prevent or reverse remodeling
2018
·
Elizabeth M. Rosethorne
, Steven J. Charlton
·
Journal of Experimental Pharmacology
·
21
PDF
Long Receptor Residence Time of C26 Contributes to Super Agonist Activity at the Human β2 Adrenoceptor
2016
·
Elizabeth M. Rosethorne
, Michelle E. Bradley
, et al.
·
Molecular Pharmacology
·
17
PDF
Endogenous lysophosphatidic acid (LPA1) receptor agonists demonstrate ligand bias between calcium and ERK signalling pathways in human lung fibroblasts
2016
·
Afrah Sattikar
, Mark R Dowling
, et al.
·
British Journal of Pharmacology
·
15
PDF
Functional desensitization of the β2 adrenoceptor is not dependent on agonist efficacy
2015
·
Elizabeth M. Rosethorne
, Michelle E. Bradley
, et al.
·
Pharmacology Research & Perspectives
·
14
PDF
High Throughput Mutagenesis for Identification of Residues Regulating Human Prostacyclin (hIP) Receptor Expression and Function
2014
·
Anke Bill
, Elizabeth M. Rosethorne
, et al.
·
PLoS ONE
·
14
PDF
ATP priming of macrophage-derived chemokine responses in CHO cells expressing the CCR4 receptor
2004
·
ElizabethM. Rosethorne
, JulietR. Leighton-Davies
, et al.
·
Naunyn-Schmiedeberg s Archives of Pharmacology
·
12
Mechanisms that matter: unbiased cellular screening for degraders
2025
·
Helen E. Burston
, Elizabeth M. Rosethorne
, et al.
·
npj Drug Discovery.
·
7
PDF
Design and synthesis of a library of chemokine antagonists
2011
·
Gurdip Bhalay
, Birgit Albrecht
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
7
The Use of Cold Plasma Technology to Reduce Carryover in Screening Assays
2013
·
Mohammed Akhlaq
, Elizabeth M. Rosethorne
, et al.
·
SLAS TECHNOLOGY
·
2
PDF
Abstract LB030: Building a platform of validated high throughput screening approaches for molecular glue degrader identification
2024
·
Allan Jordan
, Philip Addis
, et al.
·
Cancer Research
·
1
Abstract 5014: Profile of ARX001822, a highly potent, selective and orally bioavailable A2a antagonist effective in preventing adenosinergic suppression of T cell activation
2019
·
Peter M. Finan
, Roy Pettipher
, et al.
·
Cancer Research
·
1
Show more works
View as search
Works count:
27
Citation count:
1,200
H-index:
16
I10-index:
20
Year
Topic
Type
