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Manfred Gerken

Elucidation of the mechanism enabling tumor selective prodrug monotherapy.
1998 · K Bosslet, R Straub, et al. · PubMed · 225
Expression and function of β-glucuronidase in pancreatic cancer: potential role in drug targeting
2000 · Bernhard Sperker, Ulrike Werner, et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 94
Prodrugs of Anthracyclines for Use in Antibody-Directed Enzyme Prodrug Therapy
1998 · Jean-Claude Florent, Xia Dong, et al. · Journal of Medicinal Chemistry · 86
Synthesis of antigenic determinants of the Brucella a antigen, utilizing methyl 4-azido-4,6-dideoxy-α-d-mannopyranoside efficiently derived from d-mannose
1988 · David R. Bundle, Manfred Gerken, et al. · Carbohydrate Research · 73
Synthesis of the E-D-C trisaccharide unit of aureolic acid cytostatics
1985 · Joachim Thiem, Manfred Gerken · The Journal of Organic Chemistry · 63
Dose Optimization of a Doxorubicin Prodrug (HMR 1826) in Isolated Perfused Human Lungs: Low Tumor pH Promotes Prodrug Activation by β-Glucuronidase
2002 · Thomas E. Mürdter, Godehard Friedel, et al. · Journal of Pharmacology and Experimental Therapeutics · 56
Two-dimensional nuclear magnetic resonance at 500 MHz: the structural elucidation of a Salmonella serogroup N polysaccharide antigen
1986 · David R. Bundle, Manfred Gerken, et al. · Canadian Journal of Chemistry · 42
Darstellung Von β-D-Olivosyl(1→3)-D-olivosiden Aus Mithramycin
1982 · Joachim Thiem, Manfred Gerken · Journal of Carbohydrate Chemistry · 33
Glucuronide prodrugs of hydroxy compounds for antibody directed enzyme prodrug therapy (ADEPT) : A phenol nitrogen mustard carbamate
1997 · F. Schmidt, J.C. Florent, et al. · Bioorganic & Medicinal Chemistry Letters · 32
Synthese des Tetradesoxydisaccharids D‐C der Aureolsäuren
1983 · Joachim Thiem, Manfred Gerken, et al. · Liebigs Annalen der Chemie · 30
Neue synthesen von aureolsäuretrisacchariden
1987 · Joachim Thiem, Manfred Gerken, et al. · Carbohydrate Research · 27
Semisynthetic β-Rhodomycins: A New Approach to the Synthesis of 4-O-Methyl-β-Rhodomycins
1990 · Cenek Kolar, Konrad Dehmel, et al. · Journal of Carbohydrate Chemistry · 17
Application of the ADEPT strategy to the MDR resistance in cancer chemotherapy.
1999 · S Desbene, H D Van, et al. · PubMed · 13
Semisynthetic ∊-Isorhodomycins: Glycosylation and Modification Reactions1
1989 · Cenek Kolar, Konrad Dehmel, et al. · Journal of Carbohydrate Chemistry · 12
2,6‐Didesoxysaccharidglycoside von α‐Hydroxyketonen: Aufbau und Konfigurationsermittlung von Glycosiden mit der Tetralon‐Unterstruktur des Olivomycins
1983 · Joachim Thiem, Manfred Gerken, et al. · Liebigs Annalen der Chemie · 12
Synthesis and cytotoxic activity of a glucuronylated prodrug of nornitrogen mustard
2000 · Sébastien Papot, Damien Combaud, et al. · Bioorganic & Medicinal Chemistry Letters · 11
Human erythropoietin-specific sites of monoclonal antibody-mediated neutralization
1993 · MR Fibi, M Aslan, et al. · Blood · 9
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Synthesis of 2′-Iodo Analogues of β-Rhodomycins1
1989 · Manfred Gerken, Sabine Blank, et al. · Journal of Carbohydrate Chemistry · 5
Semisynthetic 4-O-Methyl-ß-Rhodomycins: Synthesis and Structure-Activity Relationships
1990 · Cenek Kolar, Manfred Gerken, et al. · Journal of Carbohydrate Chemistry · 4
Photolytic N-Mono-Demethylation of Rhodosaminylanthracyclinone Type Anthracyclines1
1990 · P. Hermentin, Ernst Raab, et al. · Journal of Carbohydrate Chemistry · 3
Synthesis and Structure Elucidation ofp-Methoxybenzoyl Derivatives of Rhodomycins1
1989 · Peter Hermentin, Ernst Raab, et al. · Journal of Carbohydrate Chemistry · 3
Synthesis of immunologically active oligosaccharide determinants of the Brucella A antigen: utilization of intermediates derived from methyl 4-azido-4,6-dideoxy-α-d-mannopyranoside
1987 · Manfred Gerken, David Bundle · Tetrahedron Letters · 1
Semisynthetic Rhodomycins and Anthracycline Prodrugs
1994 · Cenek Kolar, Klaus Bosslet, et al. · ACS symposium series
ChemInform Abstract: Semisynthetic β‐Rhodomycins: A New Approach to the Synthesis of 4‐ O‐Methyl‐β‐rhodomycins.
1991 · C. KOLAR, K. DEHMEL, et al. · ChemInform
ChemInform Abstract: Semisynthetic 4‐O‐Methyl‐β‐rhodomycins: Synthesis and Structure‐ Activity Relationships.
1991 · C. KOLAR, M. GERKEN, et al. · ChemInform
Works count: 29
Citation count: 851
H-index: 13
I10-index: 16
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