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Evy Lobbestael
Observed names:
E. Lobbestael,
Lobbestael Evy,
Lobbestael, E,
Lobbestael, E.,
Lobbestael, Evy
Institution:
KU Leuven
Observed institutions:
Consejo Superior de Investigaciones Científicas,
Instituto de Parasitología y Biomedicina "López - Neyra",
KU Leuven
ORCID:
0000-0002-6417-4670
Observed ORCID:
0000-0002-6417-4670
OpenAlex ID:
A5089341251
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
2014
·
Alexandria Beilina
, Iakov N. Rudenko
, et al.
·
Proceedings of the National Academy of Sciences
·
357
Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
2009
·
Loukia Parisiadou
, Chengsong Xie
, et al.
·
Journal of Neuroscience
·
306
PDF
MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein
2012
·
Hyun Jin Cho
, Guoxiang Liu
, et al.
·
Human Molecular Genetics
·
259
Inflammatory bowel disease and Parkinson’s disease: common pathophysiological links
2020
·
Ho-Su Lee
, Evy Lobbestael
, et al.
·
Gut
·
152
PDF
Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant
2010
·
Veronique Daniëls
, Renée Vancraenenbroeck
, et al.
·
Journal of Neurochemistry
·
127
Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation
2018
·
Jesús Madero-Pérez
, Elena Fdez
, et al.
·
Molecular Neurodegeneration
·
110
PDF
LRRK2 Kinase Activity Is Dependent on LRRK2 GTP Binding Capacity but Independent of LRRK2 GTP Binding
2011
·
Jean-Marc Taymans
, Renée Vancraenenbroeck
, et al.
·
PLoS ONE
·
107
PDF
Biochemical Characterization of Highly Purified Leucine-Rich Repeat Kinases 1 and 2 Demonstrates Formation of Homodimers
2012
·
Laura Civiero
, Renée Vancraenenbroeck
, et al.
·
PLoS ONE
·
99
PDF
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle
2013
·
Evy Lobbestael
, Jing Zhao
, et al.
·
Biochemical Journal
·
96
RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase–mediated centrosomal cohesion and ciliogenesis deficits
2019
·
Antonio Jesús Lara Ordónez
, Belén Fernández
, et al.
·
Human Molecular Genetics
·
91
PDF
Pharmacological LRRK2 kinase inhibition induces LRRK2 protein destabilization and proteasomal degradation
2016
·
E. Lobbestael
, L. Civiero
, et al.
·
Scientific Reports
·
73
PDF
Multiple-Hit Hypothesis in Parkinson’s Disease: LRRK2 and Inflammation
2020
·
Diego Cabezudo
, Veerle Baekelandt
, et al.
·
Frontiers in Neuroscience
·
70
PDF
Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brain
2015
·
Laura Civiero
, Maria Daniela Cirnaru
, et al.
·
Journal of Neurochemistry
·
66
PDF
PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2
2017
·
Laura Civiero
, Susanna Cogo
, et al.
·
Frontiers in Molecular Neuroscience
·
57
PDF
Kinase inhibition of G2019S-LRRK2 enhances autolysosome formation and function to reduce endogenous alpha-synuclein intracellular inclusions
2020
·
Julia Obergasteiger
, Giulia Frapporti
, et al.
·
Cell Death Discovery
·
56
PDF
In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2
2014
·
Renée Vancraenenbroeck
, Joren De Raeymaecker
, et al.
·
Frontiers in Molecular Neuroscience
·
56
PDF
Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues
2020
·
Lucia Iannotta
, Alice Biosa
, et al.
·
Cells
·
54
PDF
Differential protein–protein interactions of LRRK 1 and LRRK 2 indicate roles in distinct cellular signaling pathways
2014
·
Lauran Reyniers
, Maria Grazia Del Giudice
, et al.
·
Journal of Neurochemistry
·
50
PDF
Phosphorylation of LRRK2: from kinase to substrate
2012
·
Evy Lobbestael
, Veerle Baekelandt
, et al.
·
Biochemical Society Transactions
·
45
RAB7L1-Mediated Relocalization of LRRK2 to the Golgi Complex Causes Centrosomal Deficits via RAB8A
2018
·
Jesús Madero-Pérez
, Belén Fernández
, et al.
·
Frontiers in Molecular Neuroscience
·
43
PDF
Immunohistochemical detection of transgene expression in the brain using small epitope tags
2010
·
Evy Lobbestael
, Veerle Reumers
, et al.
·
BMC Biotechnology
·
41
PDF
Long-Term Overexpression of Human Wild-Type and T240R Mutant Parkin in Rat Substantia Nigra Induces Progressive Dopaminergic Neurodegeneration
2014
·
Anne-Sophie Van Rompuy
, Evy Lobbestael
, et al.
·
Journal of Neuropathology & Experimental Neurology
·
38
Rab32 interacts with SNX6 and affects retromer-dependent Golgi trafficking
2019
·
Dieter Waschbüsch
, Nicole Hübel
, et al.
·
PLoS ONE
·
36
PDF
ATP13A2 Regulates Cellular α-Synuclein Multimerization, Membrane Association, and Externalization
2021
·
Jianmin Si
, Chris Van den Haute
, et al.
·
International Journal of Molecular Sciences
·
31
PDF
Kinases as Targets for Parkinson's Disease: From Genetics to Therapy
2011
·
Renee Vancraenenbroeck
, Evy Lobbestael
, et al.
·
CNS & Neurological Disorders - Drug Targets
·
30
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Works count:
80
Citation count:
2,644
H-index:
26
I10-index:
33
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