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Rajesh P. Chavan

Observed names: Chavan, R., R Chavan, R. Chavan, R.P. Chavan, Rajesh Chavan
Institution: Wockhardt (India)
ORCID: 0000-0001-5611-5251
Observed ORCID: 0000-0001-5611-5251
OpenAlex ID: A5089607480
Levonadifloxacin, a Novel Broad-Spectrum Anti-MRSA Benzoquinolizine Quinolone Agent: Review of Current Evidence
2019 · Sachin S. Bhagwat, Manohar Nandanwar, et al. · Drug Design Development and Therapy · 78
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Plasma and Intrapulmonary Concentrations of Cefepime and Zidebactam following Intravenous Administration of WCK 5222 to Healthy Adult Subjects
2018 · Keith A. Rodvold, Mark H. Gotfried, et al. · Antimicrobial Agents and Chemotherapy · 50
Single-Center Evaluation of the Pharmacokinetics of WCK 5222 (Cefepime-Zidebactam Combination) in Subjects with Renal Impairment
2018 · Richard A. Preston, Grigor Mamikonyan, et al. · Antimicrobial Agents and Chemotherapy · 46
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Efficacy and Safety of a Novel Broad-Spectrum Anti-MRSA Agent Levonadifloxacin Compared with Linezolid for Acute Bacterial Skin and Skin Structure Infections: A Phase 3, Openlabel, Randomized Study.
2020 · A Bhatia, M Mastim, et al. · PubMed · 26
Role of cancer antigen-125 from pleural & ascitic fluid samples in non malignant conditions.
2007 · Yatiraj Kalantri, Girish Naik, et al. · PubMed · 23
Safety, Tolerability, and Pharmacokinetics of Oral Nafithromycin (WCK 4873) after Single or Multiple Doses and Effects of Food on Single-Dose Bioavailability in Healthy Adult Subjects
2019 · Piotr Iwanowski, Ashima Bhatia, et al. · Antimicrobial Agents and Chemotherapy · 14
Assessment of the in vitro cytochrome P450 (CYP) inhibition potential of nafithromycin, a next generation lactone ketolide antibiotic
2020 · Rajesh Chavan, Vineet Zope, et al. · Xenobiotica · 13
WCK 4873 (Nafithromycin): Assessment of In Vitro Human CYP Inhibitory Potential of a Novel Lactone-Ketolide
2016 · Rajesh Chavan, Vineet Zope, et al. · Open Forum Infectious Diseases · 11
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WCK 4034: A promising oxazolidinone for treating gram positive infections
2022 · Satish Bhawsar, Shivaji Pawar, et al. · Bioorganic & Medicinal Chemistry Letters · 10
Single-Center Investigation of the Pharmacokinetics of WCK 4282 (Cefepime-Tazobactam Combination) in Renal Impairment
2019 · Richard A. Preston, Grigor Mamikonyan, et al. · Antimicrobial Agents and Chemotherapy · 10
Simple liquid chromatography–tandem mass spectrometry method for determination of novel anti-methicillin-resistant Staphylococcus aureus fluoroquinolone WCK 771 in human serum
2006 · R.D. Yeole, V.L. Kulkarni, et al. · Journal of Chromatography B · 9
In Vivo Pharmacokinetic/Pharmacodynamic Targets of Levonadifloxacin against Staphylococcus aureus in a Neutropenic Murine Lung Infection Model
2019 · Sachin S. Bhagwat, Hariharan Periasamy, et al. · Antimicrobial Agents and Chemotherapy · 8
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Simultaneous determination of zidebactam and cefepime in dog plasma by LC–MS/MS and its application to pre‐clinical pharmacokinetic study
2018 · Kiran Patil, Harshad Tambe, et al. · Biomedical Chromatography · 8
Efficacy and safety of a 3-day once-daily regimen of oral nafithromycin in comparison to oral moxifloxacin for the treatment of community-acquired bacterial pneumonia in adults: a phase III, randomized, double-blind controlled trial
2025 · Himanshu Pophale, Monica Gupta, et al. · The Lancet Regional Health - Southeast Asia · 6
Cefepime pharmacodynamic targets against Enterobacterales employing neutropenic murine lung infection and in vitro pharmacokinetic models
2022 · Anouk E Muller, Marie Attwood, et al. · Journal of Antimicrobial Chemotherapy · 6
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Preclinical safety evaluation of nafithromycin (WCK 4873) with emphasis on liver safety in rat and dog
2021 · Manohar Nandanwar, Rajesh Chavan, et al. · Regulatory Toxicology and Pharmacology · 6
Identification of metabolites of novel Anti‐MRSA fluoroquinolone WCK 771 in mouse, rat, rabbit, dog, monkey and human urine using liquid chromatography tandem mass spectrometry
2019 · Ravindra D. Yeole, Vipul P. Rane, et al. · Biomedical Chromatography · 6
Assessment of in vitro inhibitory effects of novel anti MRSA benzoquinolizine fluoroquinolone WCK 771 (levonadifloxacin) and its metabolite on human liver cytochrome P450 enzymes
2020 · Rajesh Chavan, Vineet Zope, et al. · Xenobiotica · 5
LC-MS/MS method for the simultaneous estimation of Cefepime and Tazobactam in dog plasma
2019 · Kiran R. Patil, Sukanta K. Naik, et al. · Drug Analytical Research · 5
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Investigations on In Vivo Pharmacokinetic/Pharmacodynamic Determinants of Fosfomycin in Murine Thigh and Kidney Infection Models
2022 · Rajesh Chavan, Bhushan Naphade, et al. · Microbial Drug Resistance · 4
In Vitro Activity of Fosfomycin and Nitrofurantoin Against Contemporary Enterobacterales Pathogens Isolated from Indian Tertiary Care Hospitals
2020 · Rajesh Chavan, Bhushan Naphade, et al. · Microbial Drug Resistance · 4
Serum Pharmacokinetics and Bone Penetration of Novel Broad-Spectrum Anti-MRSA Agent Levonadifloxacin in Wistar Rats
2024 · Rajesh Chavan, Vineet Zope, et al. · Microbial Drug Resistance · 2
In-vitro antibacterial activity of Fosfomycin and Nitrofurantoin against Pseudomonas aeruginosa and Acinetobacter baumannii against clinical isolates collected from Indian tertiary care hospitals
2022 · Rajesh Chavan, Bhushan Naphade, et al. · Journal of Drug Delivery and Therapeutics · 2
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Some biochemical markers in various neoplasms: A multivariate analysis
1996 · Bhawana Nigam, S. P. Joshi, et al. · Indian Journal of Clinical Biochemistry · 2
Simultaneous determination of novel β‐lactamase inhibitor WCK 4234 and Meropenem in dog plasma by LC–MS/MS and its application to preclinical pharmacokinetic study
2022 · Kiran Patil, Amin Pathan, et al. · Biomedical Chromatography · 1
Works count: 28
Citation count: 355
H-index: 10
I10-index: 10
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