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Author

Chuanzheng Zhou

Observed names: C. Zhou, C.Z. Zhou, Chuan-zheng Zhou, Chuanzheng, Z., Zhou, C.
Observed institutions: Goethe University Frankfurt, Uppsala University, Johns Hopkins University, Huaibei Normal University, University of Southern Denmark, Aarhus University, Nankai University, Rega Institute for Medical Research, Collaborative Innovation Center of Chemical Science and Engineering Tianjin, Max Planck Institute of Molecular Cell Biology and Genetics, State Key Laboratory of Medicinal Chemical Biology, State Key Laboratory of Elemental Organic Chemistry, KU Leuven
ORCID: 0000-0002-0811-7794
Observed ORCID: 0000-0002-0811-7794
OpenAlex ID: A5089622339
A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
2009 · Jesper B. Bramsen, Maria B. Laursen, et al. · Nucleic Acids Research · 371
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Thiol Specific and Tracelessly Removable Bioconjugation via Michael Addition to 5-Methylene Pyrrolones
2017 · Yingqian Zhang, Xiaoping Zhou, et al. · Journal of the American Chemical Society · 127
5-Formylcytosine Yields DNA–Protein Cross-Links in Nucleosome Core Particles
2017 · Fengchao Li, Yingqian Zhang, et al. · Journal of the American Chemical Society · 110
Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones
2020 · Yingqian Zhang, Chuanlong Zang, et al. · Nature Communications · 88
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Mechanistic Studies on Histone Catalyzed Cleavage of Apyrimidinic/Apurinic Sites in Nucleosome Core Particles
2012 · Chuanzheng Zhou, Jonathan T. Sczepanski, et al. · Journal of the American Chemical Society · 79
Synthesis and biological applications of fluoro-modified nucleic acids
2017 · Fengmin Guo, Qiang Li, et al. · Organic & Biomolecular Chemistry · 70
Nucleosome Core Particle-Catalyzed Strand Scission at Abasic Sites
2013 · Jonathan T. Sczepanski, Chuanzheng Zhou, et al. · Biochemistry · 55
Histone Modification via Rapid Cleavage of C4′-Oxidized Abasic Sites in Nucleosome Core Particles
2013 · Chuanzheng Zhou, Jonathan T. Sczepanski, et al. · Journal of the American Chemical Society · 50
2-(4-Tolylsulfonyl)ethoxymethyl (TEM)—a new 2′-OH protecting group for solid-supported RNA synthesis
2006 · Chuanzheng Zhou, Dmytro Honcharenko, et al. · Organic & Biomolecular Chemistry · 50
A light-responsive, self-immolative linker for controlled drug delivery via peptide- and protein-drug conjugates
2019 · Chuanlong Zang, Huawei Wang, et al. · Chemical Science · 48
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In vivo efficacy and off-target effects of Locked Nucleic Acid (LNA) and Unlocked Nucleic Acid (UNA) modified siRNA and small internally segmented interfering RNA (sisiRNA) in mice bearing human tumor xenografts
2010 · O.R. Mook, Jeroen Vreijling, et al. · Artificial DNA PNA & XNA · 48
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Fine Tuning of Electrostatics around the Internucleotidic Phosphate through Incorporation of Modified 2′,4′-Carbocyclic-LNAs and -ENAs Leads to Significant Modulation of Antisense Properties
2008 · Chuanzheng Zhou, Yi Liu, et al. · The Journal of Organic Chemistry · 47
Modulation of Pyrene Fluorescence in DNA Probes Depends upon the Nature of the Conformationally Restricted Nucleotide
2008 · Dmytro Honcharenko, Chuanzheng Zhou, et al. · The Journal of Organic Chemistry · 47
Intramolecular Free-Radical Cyclization Reactions on Pentose Sugars for the Synthesis of Carba-LNA and Carba-ENA and the Application of Their Modified Oligonucleotides as Potential RNA Targeted Therapeutics
2012 · Chuanzheng Zhou, Jyoti Chattopadhyaya · Chemical Reviews · 46
4′-Fluorinated RNA: Synthesis, Structure, and Applications as a Sensitive 19F NMR Probe of RNA Structure and Function
2020 · Qiang Li, Jialiang Chen, et al. · Journal of the American Chemical Society · 45
Peptide Stapling by Crosslinking Two Amines with α‐Ketoaldehydes through Diverse Modified Glyoxal‐Lysine Dimer Linkers
2024 · Pan Guo, Xin Chu, et al. · Angewandte Chemie International Edition · 42
Histone-Catalyzed Cleavage of Nucleosomal DNA Containing 2-Deoxyribonolactone
2012 · Chuanzheng Zhou, Marc M. Greenberg · Journal of the American Chemical Society · 41
Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome
2020 · Hong Lin, Xiaozhe Zhang, et al. · Proceedings of the National Academy of Sciences · 40
Suppression of alpha-carbon racemization in peptide synthesis based on a thiol-labile amino protecting group
2023 · Yifei Zhou, Hongjun Li, et al. · Nature Communications · 35
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Oxidation of 8-Oxo-7,8-dihydro-2′-deoxyguanosine Leads to Substantial DNA-Histone Cross-Links within Nucleosome Core Particles
2018 · Jing Bai, Yingqian Zhang, et al. · Chemical Research in Toxicology · 35
Histones participate in base excision repair of 8-oxodGuo by transiently cross-linking with active repair intermediates in nucleosome core particles
2020 · Mengtian Ren, Mengdi Shang, et al. · Nucleic Acids Research · 34
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Effect of Ribose Conformation on RNA Cleavage via Internal Transesterification
2018 · Fengmin Guo, Zekun Yue, et al. · Journal of the American Chemical Society · 30
Free-Radical Ring Closure to Conformationally Locked α- l -Carba-LNAs and Synthesis of Their Oligos: Nuclease Stability, Target RNA Specificity, and Elicitation of RNase H
2010 · Qing Li, Fengfeng Yuan, et al. · The Journal of Organic Chemistry · 30
Cellular uptake of extracellular nucleosomes induces innate immune responses by binding and activating cGMP-AMP synthase (cGAS)
2020 · Huawei Wang, Chuanlong Zang, et al. · Scientific Reports · 29
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Nitrogen Mustard Induces Formation of DNA–Histone Cross-Links in Nucleosome Core Particles
2019 · Mengdi Shang, Mengtian Ren, et al. · Chemical Research in Toxicology · 28
Works count: 83
Citation count: 2,167
H-index: 27
I10-index: 50
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