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Domenico Aprile

Observed names: Aprile D, Aprile, Domenico
ORCID: 0000-0003-1166-3259
Observed ORCID: 0000-0003-1166-3259
OpenAlex ID: A5089657447
Different Stages of Quiescence, Senescence, and Cell Stress Identified by Molecular Algorithm Based on the Expression of Ki67, RPS6, and Beta-Galactosidase Activity
2021 · Nicola Alessio, Domenico Aprile, et al. · International Journal of Molecular Sciences · 92
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The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells
2019 · Nicola Alessio, Domenico Aprile, et al. · Aging · 63
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways
2024 · Yesuf Siraj, Domenico Aprile, et al. · Cell Communication and Signaling · 40
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Meta-analysis of senescent cell secretomes to identify common and specific features of the different senescent phenotypes: a tool for developing new senotherapeutics
2023 · Yo Oguma, Nicola Alessio, et al. · Cell Communication and Signaling · 34
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A comparative study on normal and obese mice indicates that the secretome of mesenchymal stromal cells is influenced by tissue environment and physiopathological conditions
2020 · Serife Ayaz-Guner, Nicola Alessio, et al. · Cell Communication and Signaling · 33
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Progression of irradiated mesenchymal stromal cells from early to late senescence: Changes in SASP composition and anti‐tumour properties
2023 · Nicola Alessio, Mustafa Burak Acar, et al. · Cell Proliferation · 31
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Loss of hierarchical imprinting regulation at the Prader–Willi/Angelman syndrome locus in human iPSCs
2018 · Duarte Pólvora-Brandão, Mariana Joaquim, et al. · Human Molecular Genetics · 31
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Impact of environmental microplastic exposure on HepG2 cells: unraveling proliferation, mitochondrial dynamics and autophagy activation
2025 · Hana Najahi, Nicola Alessio, et al. · Particle and Fibre Toxicology · 28
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Multipotent/pluripotent stem cell populations in stromal tissues and peripheral blood: exploring diversity, potential, and therapeutic applications
2024 · Domenico Aprile, Deanira Patrone, et al. · Stem Cell Research & Therapy · 28
IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors
2024 · Nicola Alessio, Domenico Aprile, et al. · Cell Communication and Signaling · 25
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MUSE Stem Cells Can Be Isolated from Stromal Compartment of Mouse Bone Marrow, Adipose Tissue, and Ear Connective Tissue: A Comparative Study of Their In Vitro Properties
2021 · Domenico Aprile, Nicola Alessio, et al. · Cells · 24
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Timely Supplementation of Hydrogels Containing Sulfated or Unsulfated Chondroitin and Hyaluronic Acid Affects Mesenchymal Stromal Cells Commitment Toward Chondrogenic Differentiation
2021 · Nicola Alessio, Antonietta Stellavato, et al. · Frontiers in Cell and Developmental Biology · 22
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Why Do Muse Stem Cells Present an Enduring Stress Capacity? Hints from a Comparative Proteome Analysis
2021 · Mustafa B. Acar, Domenico Aprile, et al. · International Journal of Molecular Sciences · 17
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Role of glycosphingolipid SSEA‐3 and FGF2 in the stemness and lineage commitment of multilineage differentiating stress enduring (MUSE) cells
2022 · Domenico Aprile, Nicola Alessio, et al. · Cell Proliferation · 12
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Terpenes: natural compounds found in plants as potential senotherapeutics targeting senescent mesenchymal stromal cells and promoting apoptosis
2025 · Valeria Mazzone, Nicola Alessio, et al. · Stem Cell Research & Therapy · 11
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Methods to Investigate the Secretome of Senescent Cells
2024 · Afshin Samiminemati, Domenico Aprile, et al. · Methods and Protocols · 10
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An Example of Neuro-Glial Commitment and Differentiation of Muse Stem Cells Obtained from Patients with IQSEC2-Related Neural Disorder: A Possible New Cell-Based Disease Model
2023 · Sura Hilal Ahmed Al Sammarraie, Domenico Aprile, et al. · Cells · 9
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Germicidal lamps using UV-C radiation may pose health safety issues: a biomolecular analysis of their effects on apoptosis and senescence
2024 · Nicola Alessio, Alessia Ambrosino, et al. · Aging · 6
The interactome era: Integrating RNA-seq, proteomics, and network biology to decode cellular senescence
2025 · Mohd Shahzaib, Domenico Aprile, et al. · Ageing Research Reviews · 5
Low-Level Radiofrequency Exposure Does Not Induce Changes in MSC Biology: An in vitro Study for the Prevention of NIR-Related Damage
2019 · Nicola Alessio, Elisa Santoro, et al. · Stem Cells and Cloning Advances and Applications · 5
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Mesenchymal Stromal Cell (MSC) Isolation and Induction of Acute and Replicative Senescence
2024 · Afshin Samiminemati, Mohd Shahzaib, et al. · Methods in molecular biology · 4
Lineage specification into GABAergic, glutamatergic, dopaminergic, and astrocytic phenotypes using MUSE stem cells: a novel approach for modeling neurodegenerative and psychiatric disorders
2025 · Domenico Aprile, Deanira Patrone, et al. · Molecular Psychiatry · 3
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Methods to Detect and Compare Cellular and Mitochondrial Changes in Senescent and Healthy Mesenchymal Stem Cells
2024 · Afshin Samiminemati, Mohd Shahzaib, et al. · Methods in molecular biology · 3
Low-Level Radiofrequency Exposure Does Not Induce Changes in MSC Biology: An in vitro Study for the Prevention of NIR-Related Damage
2019 · Alessio N, Santoro E, et al. · DOAJ (DOAJ: Directory of Open Access Journals) · 2
A conserved regulatory architecture stabilizes cellular senescence across distinct triggers in human fibroblasts
2026 · Mohd Shahzaib, Domenico Aprile, et al. · GeroScience · 1
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Works count: 48
Citation count: 537
H-index: 13
I10-index: 16
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