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Kyle Vaughn Laster

Observed names: K.V. Laster, Kyle Laster, Kyle V. Laster, Kyle Vaugh Laster, Laster, Kyle, Laster, Kyle Vaughn
ORCID: 0000-0002-8469-0015
Observed ORCID: 0000-0002-8469-0015
OpenAlex ID: A5090060636
Cdc2-like kinases: structure, biological function and therapeutic targets for diseases
2023 · Mengqiu Song, Luping Pang, et al. · Signal Transduction and Targeted Therapy · 91
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Persistent nuclear actin filaments inhibit transcription by RNA polymerase II
2016 · Leonid A. Serebryannyy, Megan Parilla, et al. · Journal of Cell Science · 76
Costunolide is a dual inhibitor of MEK1 and AKT1/2 that overcomes osimertinib resistance in lung cancer
2022 · Xueli Tian, Rui Wang, et al. · Molecular Cancer · 69
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Targeting CRAF kinase in anti-cancer therapy: progress and opportunities
2023 · Penglei Wang, Kyle Laster, et al. · Molecular Cancer · 46
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BRD4 drives esophageal squamous cell carcinoma growth by promoting RCC2 expression
2021 · Qiong Wu, Fangfang Liu, et al. · Oncogene · 45
A beginning of the end: new insights into the functional organization of telomeres
2015 · Ashley M Wood, Kyle Laster, et al. · Nucleus · 44
The comparison of cancer gene mutation frequencies in Chinese and U.S. patient populations
2022 · Fayang Ma, Kyle Laster, et al. · Nature Communications · 43
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Kcnq 1-5 (Kv7.1-5) potassium channel expression in the adult zebrafish
2014 · Calvin Wu, Kanishk Sharma, et al. · BMC Physiology · 42
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Targeting integrin αvβ3 with indomethacin inhibits patient‐derived xenograft tumour growth and recurrence in oesophageal squamous cell carcinoma
2021 · Fangfang Liu, Qiong Wu, et al. · Clinical and Translational Medicine · 40
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A novel lncRNA MTAR1 promotes cancer development through IGF2BPs mediated post-transcriptional regulation of c-MYC
2022 · Yunfeng Gao, Ming Jiang, et al. · Oncogene · 29
Novel dual inhibitor for targeting PIM1 and FGFR1 kinases inhibits colorectal cancer growth in vitro and patient-derived xenografts in vivo
2022 · Fanxiang Yin, Ran Zhao, et al. · Acta Pharmaceutica Sinica B · 28
Discovery of a novel dual-target inhibitor against RSK1 and MSK2 to suppress growth of human colon cancer
2020 · Guoguo Jin, Mingyang Yan, et al. · Oncogene · 24
Multi-omics characterization of esophageal squamous cell carcinoma identifies molecular subtypes and therapeutic targets
2024 · Dengyun Zhao, Yaping Guo, et al. · JCI Insight · 23
Toosendanin targeting eEF2 impedes Topoisomerase I & II protein translation to suppress esophageal squamous cell carcinoma growth
2023 · Xuechao Jia, Penglei Wang, et al. · Journal of Experimental & Clinical Cancer Research · 23
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2,6-DMBQ is a novel mTOR inhibitor that reduces gastric cancer growth in vitro and in vivo
2020 · Xueyin Zu, Xiaoli Ma, et al. · Journal of Experimental & Clinical Cancer Research · 23
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Advancements in therapeutic peptides: Shaping the future of cancer treatment
2024 · Xiaojie Chen, Zhiwei Zhao, et al. · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 21
Oxethazaine inhibits esophageal squamous cell carcinoma proliferation and metastasis by targeting aurora kinase A
2022 · Zhuo Bao, Ang Li, et al. · Cell Death and Disease · 21
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Anwulignan is a novel JAK1 inhibitor that suppresses non‐small cell lung cancer growth
2021 · Xiaomeng Xie, Xiangyu Wang, et al. · Journal of Cellular and Molecular Medicine · 21
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OSGIN1 is a novel TUBB3 regulator that promotes tumor progression and gefitinib resistance in non-small cell lung cancer
2023 · Xiaomeng Xie, Kyle Vaughn Laster, et al. · Cellular and Molecular Life Sciences · 19
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Harmaline isolated from Peganum harmala suppresses growth of esophageal squamous cell carcinoma through targeting mTOR
2021 · Yuanyuan Zhang, Xiaodan Shi, et al. · Phytotherapy Research · 19
Hippocalcin-like 1 is a key regulator of LDHA activation that promotes the growth of non-small cell lung carcinoma
2022 · Xiangyu Wang, Xiaomeng Xie, et al. · Cellular Oncology · 18
3-Deoxysappanchalcone Inhibits Skin Cancer Proliferation by Regulating T-Lymphokine-Activated Killer Cell-Originated Protein Kinase in vitro and in vivo
2021 · Xiaorong Fu, Ran Zhao, et al. · Frontiers in Cell and Developmental Biology · 17
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Genomic Pangea: coordinate gene regulation and cell-specific chromosomal topologies
2010 · Kyle Laster, Steven T Kosak · Current Opinion in Cell Biology · 10
Targeting FGFR1 by β,β-dimethylacrylalkannin suppresses the proliferation of colorectal cancer in cellular and xenograft models
2024 · Ran Zhao, Fanxiang Yin, et al. · Phytomedicine · 9
Targeting TAOK1 with resveratrol inhibits esophageal squamous cell carcinoma growth in vitro and in vivo
2024 · Mengqiu Song, Yingzi Qu, et al. · Molecular Carcinogenesis · 9
Works count: 73
Citation count: 860
H-index: 19
I10-index: 23
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