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Elena Fdez

Observed names: E. Fdez, Fdez, Elena
ORCID: 0000-0002-9971-848X
Observed ORCID: 0000-0002-9971-848X
OpenAlex ID: A5090189628
LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity
2014 · Patricia Gómez-Suaga, Pilar Rivero-Ríos, et al. · Human Molecular Genetics · 144
Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation
2018 · Jesús Madero-Pérez, Elena Fdez, et al. · Molecular Neurodegeneration · 110
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RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase–mediated centrosomal cohesion and ciliogenesis deficits
2019 · Antonio Jesús Lara Ordónez, Belén Fernández, et al. · Human Molecular Genetics · 91
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Vesicle pools and synapsins: New insights into old enigmas
2007 · Elena Fdez, Sabine Hilfiker · Journal of Neurocytology · 88
GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2
2017 · Marian Blanca Ramírez, Antonio Jesús Lara Ordóñez, et al. · Human Molecular Genetics · 79
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Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A
2016 · Belén Fernández, Elena Fdez, et al. · Autophagy · 54
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Transmembrane-domain determinants for SNARE-mediated membrane fusion
2010 · Elena Fdez, Mar Martínez-Salvador, et al. · Journal of Cell Science · 50
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RAB7L1-Mediated Relocalization of LRRK2 to the Golgi Complex Causes Centrosomal Deficits via RAB8A
2018 · Jesús Madero-Pérez, Belén Fernández, et al. · Frontiers in Molecular Neuroscience · 43
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Upstream deregulation of calcium signaling in Parkinson’s disease
2014 · Pilar Rivero-Ríos, Patricia Gómez-Suaga, et al. · Frontiers in Molecular Neuroscience · 37
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Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations
2020 · Pilar Rivero-Ríos, Maria Romo-Lozano, et al. · Cells · 36
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Centrosomal cohesion deficits as cellular biomarker in lymphoblastoid cell lines from LRRK2 Parkinson's disease patients
2019 · Belén Fernández, Antonio Jesús Lara Ordóñez, et al. · Biochemical Journal · 35
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A Link between Autophagy and the Pathophysiology of LRRK2 in Parkinson's Disease
2012 · Patricia Gómez-Suaga, Elena Fdez, et al. · Parkinson s Disease · 29
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The LRRK2 signaling network converges on a centriolar phospho-Rab10/RILPL1 complex to cause deficits in centrosome cohesion and cell polarization
2022 · Antonio Jesús Lara Ordóñez, Rachel Fasiczka, et al. · Biology Open · 26
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A potential patient stratification biomarker for Parkinson´s disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
2024 · Yahaira Naaldijk, Belén Fernández, et al. · npj Parkinson s Disease · 25
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Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement
2022 · Elena Fdez, Jesús Madero-Pérez, et al. · iScience · 24
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Iron-induced cytotoxicity mediated by endolysosomal TRPML1 channels is reverted by TFEB
2022 · Belén Fernández, Pablo Olmedo, et al. · Cell Death and Disease · 23
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LRRK2 and Parkinson's Disease: From Lack of Structure to Gain of Function
2016 · Marian Blanca Ramirez, Jesus Madero-Perez, et al. · Current Protein and Peptide Science · 21
Novel insights into the neurobiology underlying LRRK2-linked Parkinson's disease
2014 · P. Gómez-Suaga, E. Fdez, et al. · Neuropharmacology · 21
Evaluation of Current Methods to Detect Cellular Leucine-Rich Repeat Kinase 2 (LRRK2) Kinase Activity
2022 · Belén Fernández, Vinita G. Chittoor-Vinod, et al. · Journal of Parkinson s Disease · 15
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LRRK2: from kinase to GTPase to microtubules and back
2017 · Marian Blanca Ramírez, Antonio Jesús Lara Ordóñez, et al. · Biochemical Society Transactions · 13
A Role for Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Complex Dimerization during Neurosecretion
2008 · Elena Fdez, Thomas A. Jowitt, et al. · Molecular Biology of the Cell · 13
Cellular effects mediated by pathogenic LRRK2: homing in on Rab-mediated processes
2017 · Jesús Madero-Pérez, Elena Fdez, et al. · Biochemical Society Transactions · 10
Protocol to measure centrosome cohesion deficits mediated by pathogenic LRRK2 in cultured cells using confocal microscopy
2023 · Elena Fdez, Rachel Fasiczka, et al. · STAR Protocols · 5
A potential patient stratification biomarker for Parkinso’s disease based on LRRK2 kinase-mediated centrosomal alterations in peripheral blood-derived cells
2023 · Yahaira Naaldijk, Belén Fernández, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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LRRK2 causes centrosomal deficits via phosphorylated Rab10 and RILPL1 at centriolar subdistal appendages
2021 · Antonio Jesús Lara Ordóñez, Belén Fernández, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Works count: 41
Citation count: 995
H-index: 18
I10-index: 22
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