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Naoki Umemura
Observed names:
N. Umemura,
Umemura Naoki,
Umemura, Naoki
Institution:
Asahi University
Observed institutions:
Asahi University,
University of Pittsburgh,
Meikai University,
Josai University,
UPMC Hillman Cancer Center,
Gifu University
show all 6
ORCID:
0000-0002-3249-782X
Observed ORCID:
0000-0002-3249-782X
OpenAlex ID:
A5090200946
Works
51
Awards
3
Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics
2008
·
Naoki Umemura
, Masanao Saio
, et al.
·
Journal of Leukocyte Biology
·
349
Depletion of CD4+CD25+ regulatory T cells enhances interleukin‐2‐induced antitumor immunity in a mouse model of colon adenocarcinoma
2007
·
Hisashi Imai
, Masanao Saio
, et al.
·
Cancer Science
·
80
PDF
Alteration of metabolomic profiles by titanium dioxide nanoparticles in human gingivitis model
2015
·
Rene Garcia-Contreras
, Masahiro Sugimoto
, et al.
·
Biomaterials
·
63
Immunomodulatory aspects in the progression and treatment of oral malignancy
2019
·
Nobuo Kondoh
, Masako Mizuno-Kamiya
, et al.
·
Japanese Dental Science Review
·
58
PDF
Hyaluronan induces odontoblastic differentiation of dental pulp stem cells via CD44
2016
·
Naoki Umemura
, Emika Ohkoshi
, et al.
·
Stem Cell Research & Therapy
·
40
PDF
Defective NF-κB Signaling in Metastatic Head and Neck Cancer Cells Leads to Enhanced Apoptosis by Double-Stranded RNA
2011
·
Naoki Umemura
, Jianzhong Zhu
, et al.
·
Cancer Research
·
40
1-(3-Aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones: A novel group of tumour-selective cytotoxins
2012
·
Sinan Bilginer
, Halise Inci Gul
, et al.
·
Journal of Enzyme Inhibition and Medicinal Chemistry
·
37
PDF
Dimeric 3,5-bis(benzylidene)-4-piperidones: A novel cluster of tumour-selective cytotoxins possessing multidrug-resistant properties
2012
·
Swagatika Das
, Umashankar Das
, et al.
·
European Journal of Medicinal Chemistry
·
29
Synthesis and Cytotoxic Activities of Difluoro-Dimethoxy Chalcones
2017
·
Cem Yamali
, Halise Inci Gul
, et al.
·
Anti-Cancer Agents in Medicinal Chemistry
·
28
Synthesis and biological evaluation of 1,5-bis(4-hydroxy-3-methoxyphenyl)penta-1,4-dien-3-one and its aminomethyl derivatives
2014
·
Kadir Ozden Yerdelen
, Halise Inci Gul
, et al.
·
Journal of Enzyme Inhibition and Medicinal Chemistry
·
28
PDF
TNF expressed by tumor-associated macrophages, but not microglia, can eliminate glioma
2007
·
Jiro Nakagawa
, Masanao Saio
, et al.
·
International Journal of Oncology
·
28
PDF
Induced overexpression of CD44 associated with resistance to apoptosis on DNA damage response in human head and neck squamous cell carcinoma cells
2016
·
Emika Ohkoshi
, Naoki Umemura
·
International Journal of Oncology
·
26
PDF
Anti-UV/HIV activity of Kampo medicines and constituent plant extracts.
2012
·
Takao Kato
, Norio Horie
, et al.
·
PubMed
·
26
ABCG2, CD44 and SOX9 are increased with the acquisition of drug resistance and involved in cancer stem cell activities in head and neck squamous cell carcinoma cells
2022
·
Koichi Murakami
, Naoki Umemura
, et al.
·
Experimental and Therapeutic Medicine
·
25
PDF
3,5-Bis(3-alkylaminomethyl-4-hydroxybenzylidene)-4-piperidones: A Novel Class of Potent Tumor-Selective Cytotoxins
2016
·
Subhas S. Karki
, Umashankar Das
, et al.
·
Journal of Medicinal Chemistry
·
24
Metabolomic profiling of tumor-infiltrating macrophages during tumor growth
2020
·
Naoki Umemura
, Masahiro Sugimoto
, et al.
·
Cancer Immunology Immunotherapy
·
23
PDF
Skewing the Th cell phenotype toward Th1 alters the maturation of tumor-infiltrating mononuclear phagocytes
2008
·
Kenichi Nonaka
, Masanao Saio
, et al.
·
Journal of Leukocyte Biology
·
23
Th1 polarization in the tumor microenvironment upregulates the myeloid-derived suppressor-like function of macrophages
2021
·
Kenichi Nonaka
, Masanao Saio
, et al.
·
Cellular Immunology
·
20
PDF
Shikonin induces odontoblastic differentiation of dental pulp stem cells via AKT–mTOR signaling in the presence of CD44
2020
·
Kunihiro Kajiura
, Naoki Umemura
, et al.
·
Connective Tissue Research
·
19
PDF
Preoperative radiotherapy contributes to induction of proliferative activity of CD8+ tumor-infiltrating T-cells in oral squamous cell carcinoma
2006
·
Tatsuhiko Suwa
, Masanao Saio
, et al.
·
Oncology Reports
·
19
PDF
Synthesis and Cytotoxic Activities of a Curcumin Analogue and Its bis- Mannich Derivatives
2015
·
Kadir Yerdelen
, Halise Gul
, et al.
·
Letters in Drug Design & Discovery
·
18
Tumor growth limited to subcutaneous site vs tumor growth in pulmonary site exhibit differential effects on systemic immunities
2017
·
Junko Masuda
, Eiji Takayama
, et al.
·
Oncology Reports
·
17
PDF
Tumour-specific cytotoxicity and structure–activity relationships of novel 1-[3-(2-methoxyethylthio)propionyl]-3,5-bis(benzylidene)-4-piperidones
2016
·
Mohammad Hossain
, Umashankar Das
, et al.
·
Bioorganic & Medicinal Chemistry
·
17
Cytotoxicity of dental compounds towards human oral squamous cell carcinoma and normal oral cells.
2013
·
Teho Koh
, Mamoru Machino
, et al.
·
PubMed
·
16
Synthesis and Cytotoxicities of New Azafluorenones with Apoptotic Mechanism of Action and Cell Cycle Analysis
2018
·
Halise Inci Gul
, Mehtap Tugrak
, et al.
·
Anti-Cancer Agents in Medicinal Chemistry
·
15
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Works count:
51
Citation count:
1,186
H-index:
19
I10-index:
32
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