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Eiichi Tokuda

Observed names: E. Tokuda, Ei Ichi Tokuda, Ei-Ichi Tokuda, Ei-ichi Tokuda, Tokuda Eiichi, Tokuda, Eiichi, 徳田, 栄一, 栄一 徳田
ORCID: 0000-0002-7690-3025
Observed ORCID: 0000-0002-7690-3025
OpenAlex ID: A5090692508
Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31
2017 · Taro Ishiguro, Nozomu Sato, et al. · Neuron · 138
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Dysregulation of intracellular copper homeostasis is common to transgenic mice expressing human mutant superoxide dismutase-1s regardless of their copper-binding abilities
2013 · Eiichi Tokuda, Eriko Okawa, et al. · Neurobiology of Disease · 85
Wild-type Cu/Zn-superoxide dismutase is misfolded in cerebrospinal fluid of sporadic amyotrophic lateral sclerosis
2019 · Eiichi Tokuda, Yo-ichi Takei, et al. · Molecular Neurodegeneration · 79
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Copper Homeostasis as a Therapeutic Target in Amyotrophic Lateral Sclerosis with SOD1 Mutations
2016 · Eiichi Tokuda, Yoshiaki Furukawa · International Journal of Molecular Sciences · 76
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Metallothionein proteins expression, copper and zinc concentrations, and lipid peroxidation level in a rodent model for amyotrophic lateral sclerosis
2006 · Eiichi Tokuda, Shin-Ichi Ono, et al. · Toxicology · 76
Ammonium tetrathiomolybdate delays onset, prolongs survival, and slows progression of disease in a mouse model for amyotrophic lateral sclerosis
2008 · Eiichi Tokuda, Shin-ichi Ono, et al. · Experimental Neurology · 72
Dysregulation of intracellular copper trafficking pathway in a mouse model of mutant copper/zinc superoxide dismutase‐linked familial amyotrophic lateral sclerosis
2009 · Eiichi Tokuda, Eriko Okawa, et al. · Journal of Neurochemistry · 69
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Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase-1
2013 · E. Tokuda, E. Okawa, et al. · Human Molecular Genetics · 48
A misfolded dimer of Cu/Zn‐superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis
2016 · Itsuki Anzai, Eiichi Tokuda, et al. · Protein Science · 45
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Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase
2016 · Eiichi Tokuda, Thomas Brännström, et al. · Acta Neuropathologica Communications · 41
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Does wild-type Cu/Zn-superoxide dismutase have pathogenic roles in amyotrophic lateral sclerosis?
2020 · Yoshiaki Furukawa, Eiichi Tokuda · Translational Neurodegeneration · 39
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A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis
2018 · Eiichi Tokuda, Takao Nomura, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 34
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Regulation of Intracellular Copper by Induction of Endogenous Metallothioneins Improves the Disease Course in a Mouse Model of Amyotrophic Lateral Sclerosis
2015 · Eiichi Tokuda, Shunsuke Watanabe, et al. · Neurotherapeutics · 29
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Screening of Drugs Inhibiting In vitro Oligomerization of Cu/Zn-Superoxide Dismutase with a Mutation Causing Amyotrophic Lateral Sclerosis
2016 · Itsuki Anzai, Keisuke Toichi, et al. · Frontiers in Molecular Biosciences · 28
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Stagnation of glymphatic interstitial fluid flow and delay in waste clearance in the SOD1-G93A mouse model of ALS
2020 · Mikako Hirose, Mito Asano, et al. · Neuroscience Research · 26
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Oxidative misfolding of Cu/Zn-superoxide dismutase triggered by non-canonical intramolecular disulfide formation
2019 · Itsuki Anzai, Eiichi Tokuda, et al. · Free Radical Biology and Medicine · 26
Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis
2017 · Eiichi Tokuda, Itsuki Anzai, et al. · Molecular Neurodegeneration · 24
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An essential role of N-terminal domain of copper chaperone in the enzymatic activation of Cu/Zn-superoxide dismutase
2017 · Mami Fukuoka, Eiichi Tokuda, et al. · Journal of Inorganic Biochemistry · 22
FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD
2023 · Yuzo Fujino, Morio Ueyama, et al. · eLife · 20
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FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD
2023 · Yuzo Fujino, Morio Ueyama, et al. · eLife · 17
Dysequilibrium between caspases and their inhibitors in a mouse model for amyotrophic lateral sclerosis
2007 · Eiichi Tokuda, Shin-ichi Ono, et al. · Brain Research · 16
Upregulation of Metallothionein-I mRNA Expression in a Rodent Model for Amyotrophic Lateral Sclerosis
2006 · Shin-Ichi Ono, Yuko Endo, et al. · Biological Trace Element Research · 16
A Metal-Free, Disulfide Oxidized Form of Superoxide Dismutase 1 as a Primary Misfolded Species with Prion-Like Properties in the Extracellular Environments Surrounding Motor Neuron-Like Cells
2021 · Chika Takashima, Yasuhiro Kosuge, et al. · International Journal of Molecular Sciences · 10
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Abnormal protein oligomers for neurodegeneration
2017 · Eiichi Tokuda, Yoshiaki Furukawa · Oncotarget · 9
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Different patterns in the induction of metallothionein mRNA synthesis among isoforms after acute ethanol administration
2007 · Shin-Ichi Ono, Yuriko Ishizaki, et al. · Biological Trace Element Research · 9
Works count: 62
Citation count: 1,076
H-index: 19
I10-index: 23
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