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M. Victòria Clos

Observed names: Clos M. V., Clos, M. Victoria, M. Clos, M. V. Clos, M. Victoria Clos, M.V Clos, M.V. Clos, M.Victoria Clos, M.Victòria Clos, Ma Victoria Clos Guillen, Maria Victoria Clos, Maria Victòria Clos, MªV. Clos, MÂ Victoria Clos, Victoria Clos, Victoria M. Clos
ORCID: 0000-0002-7389-3351
Observed ORCID: 0000-0002-7389-3351
OpenAlex ID: A5091388992
Novel Donepezil-Based Inhibitors of Acetyl- and Butyrylcholinesterase and Acetylcholinesterase-Induced β-Amyloid Aggregation
2008 · Pelayo Camps, Xavier Formosa, et al. · Journal of Medicinal Chemistry · 205
Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds
2009 · Pelayo Camps, Xavier Formosa, et al. · Journal of Medicinal Chemistry · 173
Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents
2014 · Elisabet Viayna, Irene Sola, et al. · Journal of Medicinal Chemistry · 154
Huprine–Tacrine Heterodimers as Anti-Amyloidogenic Compounds of Potential Interest against Alzheimer’s and Prion Diseases
2011 · Carles Galdeano, Elisabet Viayna, et al. · Journal of Medicinal Chemistry · 95
Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates
2010 · Pelayo Camps, Xavier Formosa, et al. · Chemico-Biological Interactions · 87
Synthesis and Pharmacological Evaluation of Huprine−Tacrine Heterodimers: Subnanomolar Dual Binding Site Acetylcholinesterase Inhibitors
2004 · Pelayo Camps, Xavier Formosa, et al. · Journal of Medicinal Chemistry · 70
Novel Levetiracetam Derivatives That Are Effective against the Alzheimer-like Phenotype in Mice: Synthesis, in Vitro, ex Vivo, and in Vivo Efficacy Studies
2015 · Irene Sola, Ester Aso, et al. · Journal of Medicinal Chemistry · 66
Tetrahydrobenzo[h][1,6]naphthyridine-6-chlorotacrine hybrids as a new family of anti-Alzheimer agents targeting β-amyloid, tau, and cholinesterase pathologies
2014 · Ornella Di Pietro, F. Javier Pérez-Areales, et al. · European Journal of Medicinal Chemistry · 65
Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity
2015 · Ornella Di Pietro, Esther Vicente-García, et al. · European Journal of Medicinal Chemistry · 64
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Novel Huprine Derivatives with Inhibitory Activity toward β‐Amyloid Aggregation and Formation as Disease‐Modifying Anti‐Alzheimer Drug Candidates
2010 · Elisabet Viayna, Tània Gómez, et al. · ChemMedChem · 60
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Huprine X and Huperzine A Improve Cognition and Regulate Some Neurochemical Processes Related with Alzheimer’s Disease in Triple Transgenic Mice (3xTg-AD)
2012 · M. Ratia, L. Giménez-Llort, et al. · Neurodegenerative Diseases · 50
1,2,3,4-Tetrahydrobenzo[h][1,6]naphthyridines as a new family of potent peripheral-to-midgorge-site inhibitors of acetylcholinesterase: Synthesis, pharmacological evaluation and mechanistic studies
2013 · Ornella Di Pietro, Elisabet Viayna, et al. · European Journal of Medicinal Chemistry · 49
Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides
2018 · Shaobin Yang, Sònia Pascual-Guiral, et al. · Frontiers in Aging Neuroscience · 44
Shogaol–huprine hybrids: Dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties
2014 · F. Javier Pérez-Areales, Ornella Di Pietro, et al. · Bioorganic & Medicinal Chemistry · 43
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Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis
2018 · Carles Galdeano, Nicolas Coquelle, et al. · Molecules · 37
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Effect of Huprine X on β-Amyloid, Synaptophysin and α7 Neuronal Nicotinic Acetylcholine Receptors in the Brain of 3xTg-AD and APPswe Transgenic Mice
2010 · Monika M. Hedberg, M. Victoria Clos, et al. · Neurodegenerative Diseases · 34
Involvement of Different Types of Voltage‐Sensitive Calcium Channels in the Presynaptic Regulation of Noradrenaline Release in Rat Brain Cortex and Hippocampus
1995 · Josefa Sabrià, Conxita Pastor, et al. · Journal of Neurochemistry · 33
Acetylcholinesterase as an amyloid enhancing factor in PrP82-146 aggregation process
2008 · M. Pera, A. Martínez-Otero, et al. · Molecular and Cellular Neuroscience · 26
Interaction of a new potent anticholinesterasic compound (±)huprine X with muscarinic receptors in rat brain
2002 · S. Roman, N.M. Vivas, et al. · Neuroscience Letters · 24
Behavioural effects and regulation of PKCα and MAPK by huprine X in middle aged mice
2010 · M. Ratia, L. Giménez-Llort, et al. · Pharmacology Biochemistry and Behavior · 22
Acetylcholinesterase triggers the aggregation of PrP 106–126
2006 · M. Pera, S. Román, et al. · Biochemical and Biophysical Research Communications · 22
Potentiation effects of (±)huprine X, a new acetylcholinesterase inhibitor, on nicotinic receptors in rat cortical synaptosomes
2003 · S. Roman, A. Badia, et al. · Neuropharmacology · 21
Superfusion of synaptosomes to study presynaptic mechanisms involved in neurotransmitter release from rat brain
2001 · A. Garcia-Sanz, A. Badia, et al. · Brain Research Protocols · 21
D2 dopamine receptors and modulation of spontaneous acetylcholine (ACh) release from rat striatal synaptosomes
1997 · M. V. Clos, A. García‐Sanz, et al. · British Journal of Pharmacology · 19
Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal–antiplasmodial activity
2015 · Irene Sola, Sílvia Castellà, et al. · Bioorganic & Medicinal Chemistry · 18
Works count: 69
Citation count: 1,695
H-index: 21
I10-index: 32
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