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Hartwig Hennekes
Observed names:
H HENNEKES,
H Hennekes,
H. Hennekes,
Hartwig H. Hennekes
Institution:
Bayer (Germany)
Observed institutions:
Max Planck Society,
Merck KGaA, Darmstadt (Germany),
Max Planck Institut für Zellbiologie,
ISREC Foundation,
Bayer (Germany),
University of Lausanne
show all 6
ORCID:
0009-0006-8546-5537
Observed ORCID:
0009-0006-8546-5537
OpenAlex ID:
A5091624608
Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects
2003
·
Heike Schäcke
, Arndt Schottelius
, et al.
·
Proceedings of the National Academy of Sciences
·
463
The role of isoprenylation in membrane attachment of nuclear lamins: A single point mutation prevents proteolytic cleavage of the lamin A precursor and confers membrane binding properties
1994
·
Hartwig Hennekes
, Erich A. Nigg
·
Journal of Cell Science
·
182
Dimethylfumarate Induces Immunosuppression via Glutathione Depletion and Subsequent Induction of Heme Oxygenase 1
2007
·
Joachim C.U. Lehmann
, Joanna J. Listopad
, et al.
·
Journal of Investigative Dermatology
·
165
PDF
Preclinical Efficacy of a PSMA-Targeted Thorium-227 Conjugate (PSMA-TTC), a Targeted Alpha Therapy for Prostate Cancer
2019
·
Stefanie Hammer
, Urs B. Hagemann
, et al.
·
Clinical Cancer Research
·
130
PDF
Phosphorylation on protein kinase C sites inhibits nuclear import of lamin B2.
1993
·
H Hennekes
, M Peter
, et al.
·
The Journal of Cell Biology
·
123
Mesothelin-Targeted Thorium-227 Conjugate (MSLN-TTC): Preclinical Evaluation of a New Targeted Alpha Therapy for Mesothelin-Positive Cancers
2019
·
Urs B. Hagemann
, Christine Ellingsen
, et al.
·
Clinical Cancer Research
·
117
Phosphorylation of Na,K-ATPase alpha-subunits in microsomes and in homogenates of Xenopus oocytes resulting from the stimulation of protein kinase A and protein kinase C.
1992
·
A.V. Chibalin
, L.A. Vasilets
, et al.
·
Journal of Biological Chemistry
·
112
Immunostimulatory effects of targeted thorium-227 conjugates as single agent and in combination with anti-PD-L1 therapy
2021
·
Pascale Lejeune
, Véronique Cruciani
, et al.
·
Journal for ImmunoTherapy of Cancer
·
60
PDF
Advances in Precision Oncology: Targeted Thorium-227 Conjugates As a New Modality in Targeted Alpha Therapy
2020
·
Urs B. Hagemann
, Katrine Wickstroem
, et al.
·
Cancer Biotherapy and Radiopharmaceuticals
·
56
Meeting report from the Prostate Cancer Foundation PSMA‐directed radionuclide scientific working group
2018
·
Andrea K. Miyahira
, Kenneth J. Pienta
, et al.
·
The Prostate
·
43
SEGRAs: A Novel Class of Anti-inflammatory Compounds
2002
·
H. Schäcke
, H. Hennekes
, et al.
·
Springer eBooks
·
37
Targeted thorium-227 conjugates as treatment options in oncology
2023
·
Jenny Karlsson
, Christoph A. Schatz
, et al.
·
Frontiers in Medicine
·
34
PDF
227 Th-Labeled Anti-CD22 Antibody (BAY 1862864) in Relapsed/Refractory CD22-Positive Non-Hodgkin Lymphoma: A First-in-Human, Phase I Study
2021
·
Ola Lindén
, Andrew T. Bates
, et al.
·
Cancer Biotherapy and Radiopharmaceuticals
·
33
Darolutamide Potentiates the Antitumor Efficacy of a PSMA-targeted Thorium-227 Conjugate by a Dual Mode of Action in Prostate Cancer Models
2021
·
Stefanie Hammer
, Andreas Schlicker
, et al.
·
Clinical Cancer Research
·
29
Preclinical Efficacy of a PSMA-Targeted Actinium-225 Conjugate (225Ac-Macropa-Pelgifatamab): A Targeted Alpha Therapy for Prostate Cancer
2024
·
Christoph A. Schatz
, Sabine Zitzmann-Kolbe
, et al.
·
Clinical Cancer Research
·
27
PDF
Coding sequence and flanking regions of the mouse vimentin gene
1990
·
Hartwig Hennekes
, Siegfried Kühn
, et al.
·
Molecular and General Genetics MGG
·
25
First-in-human study of a thorium-227-labeled mesothelin-targeting antibody-chelator conjugate (MSLN-TTC), in patients with malignant mesothelioma and other solid tumors
2025
·
A. Minchom
, O. Lindén
, et al.
·
ESMO Open
·
9
Control of pulsed field gel electrophoresis at short switching intervals by a microcomputer
1989
·
Hartwig Hennekes
, Siegfried Kühn
·
Analytical Biochemistry
·
7
Abstract 844: Preclinical activity of PSMA-TTC, a targeted alpha therapeutic in patient-derived prostate cancer models
2018
·
Stefanie Hammer
, Urs B. Hagemann
, et al.
·
Cancer Research
·
4
The Nuclear Lamina: Regulation of Assembly by Posttranslational Modifications
1995
·
E. A. Nigg
, H. Hennekes
·
Springer eBooks
·
4
Abstract 1141: Preclinical analysis of biodistribution and PET imaging of a zirconium-89 labeled PSMA-targeted antibody-chelator conjugate
2019
·
Stefanie Hammer
, Sabine Zitzmann-Kolbe
, et al.
·
Cancer Research
·
3
Abstract 3726: Preclinical activity of PSMA-TTC (BAY 2315497) in combination with androgen receptor antagonists in prostate cancer models
2019
·
Stefanie Hammer
, Urs B. Hagemann
, et al.
·
Cancer Research
·
3
Abstract 3311: Darolutamide potentiates the antitumor efficacy of a PSMA-targeted thorium-227 conjugate (PSMA-TTC) in a hormone-independent prostate cancer model
2022
·
Christoph Schatz
, Urs Hagemann
, et al.
·
Cancer Research
·
2
Abstract 3926: MSLN-TTC (BAY 2287411) induces immunogenic cell death and secretion of pro-inflammatory cytokines in vitro and triggers an immune memory effect against a mouse tumor model
2019
·
Urs B. Hagemann
, Pascale LeJeune
, et al.
·
Cancer Research
·
1
Abstract 3937: MSLN-TTC (BAY 2287411) demonstrates increased activity in comparison to standard of care chemotherapy in models of acquired drug resistance
2019
·
Urs B. Hagemann
, Sabine Zitzmann-Kolbe
, et al.
·
Experimental and Molecular Therapeutics
·
1
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Works count:
67
Citation count:
1,671
H-index:
16
I10-index:
16
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