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Rochelle Lear

Observed names: R Lear, Rochelle E. Lear
OpenAlex ID: A5091753055
Development of a versatile oncolytic virus platform for local intra-tumoural expression of therapeutic transgenes
2017 · Nalini Marino, Sam Illingworth, et al. · PLoS ONE · 33
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99mTc-NC100692 — a tracer for imaging vitronectin receptors associated with angiogenesis: a preclinical investigation
2008 · David Edwards, Paul Jones, et al. · Nuclear Medicine and Biology · 31
99mTc-NC100668, a new tracer for imaging venous thromboemboli: pre-clinical biodistribution and incorporation into plasma clots in vivo and in vitro
2006 · David Edwards, Joanne Lewis, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 13
Abstract 4294: GE152: In vivo detection of tumor apoptosis as a tool for assessment of therapeutic efficacy
2012 · Duncan R. R. Hiscock, Graeme McRobbie, et al. · Cancer Research · 7
99mTc-NC100668, an agent for imaging venous thromboembolism: The effect of anticoagulant or thrombolytic therapy on the uptake and retention of radioactivity in blood clots in vivo
2006 · David Edwards, Joanne Lewis, et al. · Nuclear Medicine Communications · 7
The in Vivo and in Vitro Metabolic Profile of 99mtc-nc100668, a New Tracer for Imaging Venous Thromboembolism: Identification and Biodistribution of the Principal Radiolabeled Metabolite
2006 · David Edwards, Mark Battle, et al. · Drug Metabolism and Disposition · 6
The biodistribution of NC100668 and the effect of excess NC100668 on the biodistribution and kidney retention of 99mTc-NC100668 in the rat
2007 · David Edwards, Joanne Lewis, et al. · Nuclear Medicine and Biology · 4
Abstract 4875: Developing tumor-localized, combination immunotherapies
2016 · Brian R. Champion, Nalini Rasiah, et al. · Cancer Research · 2
1003 Tumor-specific replication and immunoactivity of aCD40-producing T-SIGn vectors
2024 · Maria Stella Sasso, Meg Snowden, et al. · Journal for ImmunoTherapy of Cancer · 1
Abstract 2740: Safe and effective delivery of antibody fragments to the solid tumor microenvironment
2023 · Rachel Bergin, Amandine Pelletier, et al. · Cancer Research · 1
Abstract 5098: NG-348: a novel oncolytic virus designed to mediate anti-tumour activity via the potent and selective polyclonal activation of tumor-infiltrating T-cells
2017 · Brian R. Champion, Matthieu Besneux, et al. · Cancer Research · 1
Abstract 5746: Flexible tumor-specific cytokine and antigen delivery through the T-SIGn vector platform enables effective CAR-T cell therapy against solid tumors
2023 · Maria Stella Sasso, Rachel Bergin, et al. · Cancer Research
208 T-SIGn vector-mediated antigen “spray painting” and tumor microenvironment (TME) reprogramming to enable CAR-T cell targeting of solid tumors
2022 · Maria Stella Sasso, Rachel Bergin, et al. · Journal for ImmunoTherapy of Cancer
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1223 NG-796A: A T-SIGn vector designed to reprogram the tumor microenvironment and drive anti-tumor immunity
2022 · Manuela Zonca, Katy West, et al. · Journal for ImmunoTherapy of Cancer
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12.04 Re-directing CAR-T cells against solid tumors using T-SIGn-mediated antigen delivery and tumor microenvironment reprogramming
2022 · MS Sasso, R Bergin, et al. · Journal for ImmunoTherapy of Cancer
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Abstract 1582: T-SIGn cancer gene therapy and anti-EGFR CAR-T cells synergize in combination therapy to clear A549 lung tumor xenografts and lung metastases in NSG mice
2021 · Olmo Sonzogni, Daniel Zak, et al. · Cancer Research
Abstract 1469: Optimizing the tolerability of intravenous oncolytic viral immunotherapy administration: investigation of a low-high-high dose schedule of enadenotucirev (EnAd) administration
2019 · Hilary McElwaine-Johnn, Sam Illingworth, et al. · Cancer Research
Abstract 1469: Optimizing the tolerability of intravenous oncolytic viral immunotherapy administration: investigation of a low-high-high dose schedule of enadenotucirev (EnAd) administration
2019 · Hilary McElwaine-Johnn, Sam Illingworth, et al. · Clinical Research (Excluding Clinical Trials)
Arming the oncolytic virus enadenotucirev (EnAd) to generate enhanced locally-acting immunotherapies for cancer
2015 · Brian R Champion, Nalini Rasiah, et al. · Journal for ImmunoTherapy of Cancer
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Monitoring tumour response to anti-angiogenic therapy with an F18-labeled angiogenesis imaging agent
2009 · Lucy Allen, Mark Battle, et al. · Journal of Nuclear Medicine
Works count: 20
Citation count: 106
H-index: 6
I10-index: 3
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