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Ryo Hotta

Observed names: Hotta, R, Hotta, Ryo, R. Hotta, r. hotta
ORCID: 0000-0001-9890-8241
Observed ORCID: 0000-0001-9890-8241
OpenAlex ID: A5091865934
Development and developmental disorders of the enteric nervous system
2012 · Florian Obermayr, Ryo Hotta, et al. · Nature Reviews Gastroenterology & Hepatology · 214
Transplanted progenitors generate functional enteric neurons in the postnatal colon
2013 · Ryo Hotta, Lincon A. Stamp, et al. · Journal of Clinical Investigation · 164
White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies
2016 · Alan J. Burns, Allan M. Goldstein, et al. · Developmental Biology · 143
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Colitis promotes neuronal differentiation of Sox2+ and PLP1+ enteric cells
2017 · Jaime Belkind-Gerson, Hannah K. Graham, et al. · Scientific Reports · 111
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Colitis Induces Enteric Neurogenesis Through a 5-HT4–dependent Mechanism
2015 · Jaime Belkind-Gerson, Ryo Hotta, et al. · Inflammatory Bowel Diseases · 103
Enteric neural crest-derived cells promote their migration by modifying their microenvironment through tenascin-C production
2013 · Sophia E. Akbareian, Nandor Nagy, et al. · Developmental Biology · 80
Single-cell multiome sequencing clarifies enteric glial diversity and identifies an intraganglionic population poised for neurogenesis
2023 · Richard A. Guyer, Rhian Stavely, et al. · Cell Reports · 77
Small-Molecule Induction of Neural Crest-like Cells Derived from Human Neural Progenitors
2009 · Ryo Hotta, Lana Pepdjonovic, et al. · Stem Cells · 77
Evidence of a Myenteric Plexus Barrier and Its Macrophage-Dependent Degradation During Murine Colitis: Implications in Enteric Neuroinflammation
2021 · David Dora, Szilamer Ferenczi, et al. · Cellular and Molecular Gastroenterology and Hepatology · 72
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Isogenic enteric neural progenitor cells can replace missing neurons and glia in mice with Hirschsprung disease
2015 · R. Hotta, L. S. Cheng, et al. · Neurogastroenterology & Motility · 68
Collagen 18 and agrin are secreted by enteric neural crest cells to remodel their microenvironment and regulate their migration during ENS development
2018 · Nandor Nagy, Csilla Barad, et al. · Development · 62
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Sonic hedgehog controls enteric nervous system development by patterning the extracellular matrix
2015 · Nandor Nagy, Csilla Barad, et al. · Development · 60
Effects of tissue age, presence of neurones and endothelin-3 on the ability of enteric neurone precursors to colonize recipient gut: implications for cell-based therapies
2009 · r. hotta, r. b. anderson, et al. · Neurogastroenterology & Motility · 53
Postnatal human enteric neuronal progenitors can migrate, differentiate, and proliferate in embryonic and postnatal aganglionic gut environments
2017 · Lily S. Cheng, Ryo Hotta, et al. · Pediatric Research · 49
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Delivery of enteric neural progenitors with 5-HT4 agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in vivo
2016 · Ryo Hotta, Lily S. Cheng, et al. · Biomaterials · 49
“Too much guts and not enough brains”: (epi)genetic mechanisms and future therapies of Hirschsprung disease — a review
2019 · Emilie G. Jaroy, Lourdes Acosta-Jimenez, et al. · Clinical Epigenetics · 43
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Bowel dysfunction following pullthrough surgery is associated with an overabundance of nitrergic neurons in Hirschsprung disease
2016 · Lily S. Cheng, Dana M. Schwartz, et al. · Journal of Pediatric Surgery · 42
Potential of cell therapy to treat pediatric motility disorders
2009 · Ryo Hotta, Dipa Natarajan, et al. · Seminars in Pediatric Surgery · 42
Schwann cells in the subcutaneous adipose tissue have neurogenic potential and can be used for regenerative therapies
2022 · Rhian Stavely, Ryo Hotta, et al. · Science Translational Medicine · 38
Endoscopic delivery of enteric neural stem cells to treat Hirschsprung disease
2015 · L. S. Cheng, R. Hotta, et al. · Neurogastroenterology & Motility · 38
Enteric mesenchymal cells support the growth of postnatal enteric neural stem cells
2021 · Rhian Stavely, Sukhada Bhave, et al. · Stem Cells · 32
Enteric neuronal cell therapy reverses architectural changes in a novel diphtheria toxin-mediated model of colonic aganglionosis
2019 · Sukhada Bhave, Emily Arciero, et al. · Scientific Reports · 30
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Schwann Cells in the Aganglionic Colon of Hirschsprung Disease Can Generate Neurons for Regenerative Therapy
2022 · Weikang Pan, Ahmed A Rahman, et al. · Stem Cells Translational Medicine · 29
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Optimizing neurogenic potential of enteric neurospheres for treatment of neurointestinal diseases
2016 · Lily S. Cheng, Hannah K. Graham, et al. · Journal of Surgical Research · 29
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Stem cells for GI motility disorders
2011 · Ryo Hotta, Dipa Natarajan, et al. · Current Opinion in Pharmacology · 29
Works count: 95
Citation count: 2,156
H-index: 26
I10-index: 44
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