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Ana García‐Osta

Observed names: A García-Osta, A. Garcia-Osta, Ana Garcia-Osta, Ana Garcia-osta, Ana Garcia‐Osta, Ana García-Osta, Ana García Osta, Ana García-Osta, Ana Garcı́a-Osta, Ana Gracia Osta GarciaBarroso C Ugarte A Oyarazabal J, Ana Osta, Ana García Osta, Garcia-Osta Ana, Garcia-Osta, A., Garcia-Osta, A. (Ana), Osta, Ana Garcia
Observed institutions: WuXi AppTec (China), Tianjin Economic-Technological Development Area, Biomedical Research Networking Center on Neurodegenerative Diseases, Navarre Institute of Health Research, Centro de Investigación Médica Aplicada, Universidad de Navarra, Icahn School of Medicine at Mount Sinai
ORCID: 0000-0001-6326-9064
Observed ORCID: 0000-0001-6326-9064
OpenAlex ID: A5004762623
Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model
2009 · Ana Ricobaraza, Mar Cuadrado-Tejedor, et al. · Neuropsychopharmacology · 423
A critical role for IGF-II in memory consolidation and enhancement
2011 · Dillon Y. Chen, Sarah A. Stern, et al. · Nature · 421
Phosphodiesterases as Therapeutic Targets for Alzheimer's Disease
2012 · Ana García-Osta, Mar Cuadrado-Tejedor, et al. · ACS Chemical Neuroscience · 260
Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease
2010 · Ana Ricobaraza, Mar Cuadrado‐Tejedor, et al. · Hippocampus · 239
Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology
2010 · Luis Escribano, Ana-María Simón, et al. · Neuropsychopharmacology · 235
Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease
2011 · M Cuadrado-Tejedor, I Hervias, et al. · British Journal of Pharmacology · 210
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Tadalafil crosses the blood–brain barrier and reverses cognitive dysfunction in a mouse model of AD
2012 · Carolina García-Barroso, Ana Ricobaraza, et al. · Neuropharmacology · 185
Amyloid beta mediates memory formation
2009 · Ana Garcia-Osta, Cristina M. Alberini · Learning & Memory · 171
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Insulin‐like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice
2014 · Maria Pascual‐Lucas, Silvia Viana da Silva, et al. · EMBO Molecular Medicine · 146
Decreased levels of guanosine 3′, 5′‐monophosphate (c GMP ) in cerebrospinal fluid ( CSF ) are associated with cognitive decline and amyloid pathology in A lzheimer's disease
2014 · Ana Ugarte, Francisco Gil‐Bea, et al. · Neuropathology and Applied Neurobiology · 113
Phosphodiesterase‐5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition
2015 · Christina Alves Peixoto, Ana Karolina Santana Nunes, et al. · Mediators of Inflammation · 112
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A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer’s Disease Mice
2016 · Mar Cuadrado-Tejedor, Carolina Garcia-Barroso, et al. · Neuropsychopharmacology · 104
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MuSK Expressed in the Brain Mediates Cholinergic Responses, Synaptic Plasticity, and Memory Formation
2006 · Ana Garcia-Osta, Panayiotis Tsokas, et al. · Journal of Neuroscience · 92
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Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy
2019 · Raygene Martier, Jolanda M. Liefhebber, et al. · Molecular Therapy — Nucleic Acids · 89
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Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer’s Disease
2016 · Obdulia Rabal, Juan A. Sánchez-Arias, et al. · Journal of Medicinal Chemistry · 88
Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF
2010 · Elena Puerta, Isabel Hervias, et al. · Neurobiology of Disease · 84
BDNF mediates the neuroprotective effect of PACAP-38 on rat cortical neurons
2001 · Diana Frechilla, Ana García-Osta, et al. · Neuroreport · 80
Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease
2018 · Obdulia Rabal, Juan A. Sánchez-Arias, et al. · European Journal of Medicinal Chemistry · 71
Concomitant histone deacetylase and phosphodiesterase 5 inhibition synergistically prevents the disruption in synaptic plasticity and it reverses cognitive impairment in a mouse model of Alzheimer’s disease
2015 · M. Cuadrado-Tejedor, C. Garcia-Barroso, et al. · Clinical Epigenetics · 69
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Phenylbutyrate is a Multifaceted Drug that Exerts Neuroprotective Effects and Reverses the Alzheimer´s Disease-like Phenotype of a Commonly Used Mouse Model
2013 · Mar Cuadrado-Tejedor, Ana Ricobaraza, et al. · Current Pharmaceutical Design · 66
Chronic Mild Stress Accelerates the Onset and Progression of the Alzheimer's Disease Phenotype in Tg2576 Mice
2012 · Mar Cuadrado-Tejedor, Ana Ricobaraza, et al. · Journal of Alzheimer s Disease · 62
Differential Regulation by Methylenedioxymethamphetamine of 5‐Hydroxytryptamine1A Receptor Density and mRNA Expression in Rat Hippocampus, Frontal Cortex, and Brainstem: The Role of Corticosteroids
1997 · Norberto Aguirre, Diana Frechilla, et al. · Journal of Neurochemistry · 55
Pharmacokinetic investigation of sildenafil using positron emission tomography and determination of its effect on cerebrospinal fluid cGMP levels
2015 · Vanessa Gómez‐Vallejo, Ana Ugarte, et al. · Journal of Neurochemistry · 50
Disrupting the memory of places induced by drugs of abuse weakens motivational withdrawal in a context-dependent manner
2010 · Stephen M. Taubenfeld, Elizaveta V. Muravieva, et al. · Proceedings of the National Academy of Sciences · 49
Multitarget Approach for the Treatment of Alzheimer’s Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles
2019 · Obdulia Rabal, Juan A. Sánchez-Arias, et al. · ACS Chemical Neuroscience · 46
Works count: 85
Citation count: 4,292
H-index: 34
I10-index: 53
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