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Brett Lauring
Institution:
Kallyope (United States)
Observed institution:
Kallyope (United States)
ORCID:
0009-0007-6267-0017
Observed ORCID:
0009-0007-6267-0017
OpenAlex ID:
A5093969360
Gut enteroendocrine cell activation using a combination of GPR119 and GPR40 agonists results in synergistic hormone secretion in mice and humans
2025
·
Iyassu K. Sebhat
, Monika J.M. Murphy
, et al.
·
Cell Metabolism
·
8
Combined GPR40 and GPR119 full agonism with K‐757 and K‐833 results in robust glucose lowering and modest weight loss in overweight/obese subjects with T2DM
2025
·
Michael Crutchlow
, Jiajun Liu
, et al.
·
Diabetes Obesity and Metabolism
·
4
Combined agonism of nutrient receptors GPR40 and GPR119 with K‐757 and K‐833 results in weight loss and blood pressure reductions in obese subjects without type 2 diabetes mellitus
2025
·
Michael Crutchlow
, Jiajun Liu
, et al.
·
Diabetes Obesity and Metabolism
·
3
Discovery of Gut-Targeted GPR40 Agonist K-757 and GPR119 Agonist K-833, a Combination Treatment for Metabolic Disorders
2025
·
Christopher R. Moyes
, Shuwen He
, et al.
·
Journal of Medicinal Chemistry
·
3
TRPM 8 Antagonism with Elismetrep: A Novel Approach for Treating Migraine (S37.001)
2026
·
Brett Lauring
, Peter Goadsby
, et al.
·
Neurology
Author response for "Combined agonism of nutrient receptors GPR40 and GPR119 with K‐757 and K‐833 results in weight loss and blood pressure reductions in obese subjects without type 2 diabetes mellitus "
2025
·
Michael Crutchlow
, Jiajun Liu
, et al.
·
Publons reviews and discussion
K757 and K833 multiple-dose study in healthy subjects
2024
·
Rajkumar Chetty
, Annemarie Vance
, et al.
·
http://isrctn.com/
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Works count:
7
Citation count:
18
H-index:
3
I10-index:
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