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Li Xin
Observed names:
L Xin,
L. Xin
Institution:
University of Washington
Observed institutions:
The University of Texas MD Anderson Cancer Center,
Howard Hughes Medical Institute,
University of California, Los Angeles,
Baylor College of Medicine,
University of Washington,
Yale University,
Kyorin University Hospital,
Dan L Duncan Comprehensive Cancer Center
show all 8
ORCID:
0000-0002-7138-0042
Observed ORCID:
0000-0002-7138-0042
OpenAlex ID:
A5100343145
The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis
2005
·
Li Xin
, Devon A. Lawson
, et al.
·
Proceedings of the National Academy of Sciences
·
423
PDF
Isolation and functional characterization of murine prostate stem cells
2006
·
Devon A. Lawson
, Li Xin
, et al.
·
Proceedings of the National Academy of Sciences
·
399
Adult Murine Prostate Basal and Luminal Cells Are Self-Sustained Lineages that Can Both Serve as Targets for Prostate Cancer Initiation
2012
·
Nahyun Choi
, Boyu Zhang
, et al.
·
Cancer Cell
·
341
PDF
Basal epithelial stem cells are efficient targets for prostate cancer initiation
2010
·
Devon A. Lawson
, Yang Zong
, et al.
·
Proceedings of the National Academy of Sciences
·
275
Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation
2016
·
Thomas Welte
, Ik Sun Kim
, et al.
·
Nature Cell Biology
·
216
Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch
2013
·
J B Tennakoon
, Y Shi
, et al.
·
Oncogene
·
205
PDF
ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells
2009
·
Yang Zong
, Li Xin
, et al.
·
Proceedings of the National Academy of Sciences
·
203
Enhanced Paracrine FGF10 Expression Promotes Formation of Multifocal Prostate Adenocarcinoma and an Increase in Epithelial Androgen Receptor
2007
·
Sanaz Memarzadeh
, Li Xin
, et al.
·
Cancer Cell
·
201
PDF
Self-Renewal and Multilineage Differentiation In Vitro from Murine Prostate Stem Cells
2007
·
Li Xin
, Rita U. Lukacs
, et al.
·
Stem Cells
·
199
NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss
2006
·
Qunying Lei
, Jing Jiao
, et al.
·
Cancer Cell
·
198
PDF
In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme
2003
·
Li Xin
, Hisamitsu Ide
, et al.
·
Proceedings of the National Academy of Sciences
·
195
Prostatic inflammation enhances basal-to-luminal differentiation and accelerates initiation of prostate cancer with a basal cell origin
2013
·
Oh-Joon Kwon
, Li Zhang
, et al.
·
Proceedings of the National Academy of Sciences
·
180
Lin−Sca-1+CD49fhigh Stem/Progenitors Are Tumor-Initiating Cells in the Pten -Null Prostate Cancer Model
2009
·
David J. Mulholland
, Li Xin
, et al.
·
Cancer Research
·
179
A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues
2022
·
Adam K. Glaser
, Kevin W. Bishop
, et al.
·
Nature Methods
·
175
PDF
Regulation of the pentose phosphate pathway by an androgen receptor–mTOR-mediated mechanism and its role in prostate cancer cell growth
2014
·
E Tsouko
, A S Khan
, et al.
·
Oncogenesis
·
158
PDF
Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor
2006
·
Li Xin
, Michael A. Teitell
, et al.
·
Proceedings of the National Academy of Sciences
·
158
SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein
2017
·
C Geng
, S Kaochar
, et al.
·
Oncogene
·
125
Notch Signaling as a Regulator of the Tumor Immune Response: To Target or Not To Target?
2018
·
Mahnaz Janghorban
, Li Xin
, et al.
·
Frontiers in Immunology
·
107
PDF
Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progression
2002
·
Hisamitsu Ide
, David B. Seligson
, et al.
·
Proceedings of the National Academy of Sciences
·
105
Non-Cell-Autonomous Regulation of Prostate Epithelial Homeostasis by Androgen Receptor
2016
·
Boyu Zhang
, Oh-Joon Kwon
, et al.
·
Molecular Cell
·
96
PDF
ROCK Inhibitor Y-27632 Suppresses Dissociation-Induced Apoptosis of Murine Prostate Stem/Progenitor Cells and Increases Their Cloning Efficiency
2011
·
Li Zhang
, Joseph M. Valdez
, et al.
·
PLoS ONE
·
95
PDF
Notch and TGFβ Form a Reciprocal Positive Regulatory Loop that Suppresses Murine Prostate Basal Stem/Progenitor Cell Activity
2012
·
Joseph M. Valdez
, Li Zhang
, et al.
·
Cell stem cell
·
88
PDF
Increased Notch signalling inhibits anoikis and stimulates proliferation of prostate luminal epithelial cells
2014
·
Oh-Joon Kwon
, Joseph M. Valdez
, et al.
·
Nature Communications
·
84
Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model
2016
·
Oh-Joon Kwon
, Li Zhang
, et al.
·
Journal of Clinical Investigation
·
79
PDF
Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo
2011
·
L K Mullany
, H-Y Fan
, et al.
·
Oncogene
·
73
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Works count:
75
Citation count:
5,538
H-index:
36
I10-index:
52
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