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Bin Wang
Institution:
BridgeBio Oncology Therapeutics (United States)
Observed institutions:
University of British Columbia,
Chinese Academy of Sciences,
Institute of Genetics and Developmental Biology,
BridgeBio Oncology Therapeutics (United States)
ORCID:
0009-0006-5275-8691
Observed ORCID:
0009-0006-5275-8691
OpenAlex ID:
A5100372401
Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
2024
·
Anna E. Maciag
, James P. Stice
, et al.
·
Cancer Discovery
·
71
Improved neovascularization and wound repair by targeting human basic fibroblast growth factor (bFGF) to fibrin
2008
·
Wenxue Zhao
, Qianqian Han
, et al.
·
Journal of Molecular Medicine
·
46
BBO-10203 inhibits tumor growth without inducing hyperglycemia by blocking RAS-PI3Kα interaction
2025
·
Dhirendra K. Simanshu
, Rui Xu
, et al.
·
Science
·
40
Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
·
Cancer Discovery
·
12
Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras
2015
·
Annette Ehrhardt
, Bin Wang
, et al.
·
PLoS ONE
·
10
PDF
Supplementary Figure S2 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S5 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S1 from Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
2026
·
Anna E. Maciag
, James P. Stice
, et al.
Supplementary Figure S3 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S5 from Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
2026
·
Anna E. Maciag
, James P. Stice
, et al.
Suppl. Materials and Methods 1 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S7 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Table S2 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S4 from Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
2026
·
Anna E. Maciag
, James P. Stice
, et al.
Supplementary Figure S1 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S6 from Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
2026
·
Anna E. Maciag
, James P. Stice
, et al.
Supplementary Figure S4 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S8 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Table S3 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S3 from Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
2026
·
Anna E. Maciag
, James P. Stice
, et al.
Supplementary Table S1 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S6 from Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants
2026
·
Carlos Stahlhut
, Anna E. Maciag
, et al.
Supplementary Figure S2 from Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
2026
·
Anna E. Maciag
, James P. Stice
, et al.
Data from Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
2025
·
Anna E. Maciag
, James P. Stice
, et al.
Supplementary Figure S2 from Discovery of BBO-8520, a First-In-Class Direct and Covalent Dual Inhibitor of GTP-Bound (ON) and GDP-Bound (OFF) KRASG12C
2025
·
Anna E. Maciag
, James P. Stice
, et al.
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Works count:
33
Citation count:
179
H-index:
5
I10-index:
5
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