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Wei‐Jan Huang

HDAC8 Inhibition Specifically Targets Inv(16) Acute Myeloid Leukemic Stem Cells by Restoring p53 Acetylation
2015 · Jing Qi, Sandeep Singh, et al. · Cell stem cell · 111
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Bioavailability of iron from amino acid complex in weanling pigs
2000 · Bi Yu, Wei-Jan Huang, et al. · Animal Feed Science and Technology · 104
Novel Indole-Based Peroxisome Proliferator-Activated Receptor Agonists: Design, SAR, Structural Biology, and Biological Activities
2005 · Neeraj Mahindroo, Chien-Fu Huang, et al. · Journal of Medicinal Chemistry · 90
Propolin G, a Prenylflavanone, Isolated from Taiwanese Propolis, Induces Caspase-Dependent Apoptosis in Brain Cancer Cells
2007 · Wei-Jan Huang, Chih-Hsiang Huang, et al. · Journal of Agricultural and Food Chemistry · 89
Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Enhances Radiosensitivity and Suppresses Lung Metastasis in Breast Cancer In Vitro and In Vivo
2013 · Hui-Wen Chiu, Ya-Ling Yeh, et al. · PLoS ONE · 84
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Antihyperglycemic Effect of Catalpol in Streptozotocin-Induced Diabetic Rats
2010 · Wei-Jan Huang, Ho-Shan Niu, et al. · Journal of Natural Products · 80
Preparation and anti-inflammatory activities of diarylheptanoid and diarylheptylamine analogs
2005 · Su-Lin Lee, Wei-Jan Huang, et al. · Bioorganic & Medicinal Chemistry · 78
Synthesis and Biological Evaluation of ortho‐Aryl N‐Hydroxycinnamides as Potent Histone Deacetylase (HDAC) 8 Isoform‐Selective Inhibitors
2012 · Wei‐Jan Huang, Yi‐Ching Wang, et al. · ChemMedChem · 76
Marchantin A, a cyclic bis(bibenzyl ether), isolated from the liverwort Marchantia emarginata subsp. tosana induces apoptosis in human MCF-7 breast cancer cells
2009 · Wei-Jan Huang, Chia-Li Wu, et al. · Cancer Letters · 72
Indol-1-yl Acetic Acids as Peroxisome Proliferator-Activated Receptor Agonists: Design, Synthesis, Structural Biology, and Molecular Docking Studies
2006 · Neeraj Mahindroo, Chiung-Chiu Wang, et al. · Journal of Medicinal Chemistry · 72
Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells
2016 · Jane Ying-Chieh Lee, Ching-Wen Kuo, et al. · Frontiers in Pharmacology · 67
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Liposome encapsulation reduces cantharidin toxicity
2008 · Chun-Chao Chang, Der-Zen Liu, et al. · Food and Chemical Toxicology · 59
Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer’s disease
2020 · Hui-Ju Tseng, Mei-Hsiang Lin, et al. · European Journal of Medicinal Chemistry · 53
Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach
2017 · Kai-Cheng Hsu, Chang-Yi Liu, et al. · Scientific Reports · 53
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DUSP1 Expression Induced by HDAC1 Inhibition Mediates Gefitinib Sensitivity in Non–Small Cell Lung Cancers
2015 · Yun-Chieh Lin, Yu-Chin Lin, et al. · Clinical Cancer Research · 49
Simvastatin Reverses High Glucose-Induced Apoptosis of Mesangial Cells via Modulation of Wnt Signaling Pathway
2007 · Chun-Liang Lin, Ho Cheng, et al. · American Journal of Nephrology · 49
Osthole and imperatorin, the active constituents of Cnidium monnieri (L.) Cusson, facilitate glutamate release from rat hippocampal nerve terminals
2008 · Su-Jane Wang, Tzu-Yu Lin, et al. · Neurochemistry International · 47
Alterations in histone deacetylase 8 lead to cell migration and poor prognosis in breast cancer
2016 · Chang-Lin Hsieh, Hon-Ping Ma, et al. · Life Sciences · 45
Neurocytoprotective Effects of Aliphatic Hydroxamates from Lovastatin, a Secondary Metabolite fromMonascus-Fermented Red Mold Rice, in 6-Hydroxydopamine (6-OHDA)-Treated Nerve Growth Factor (NGF)-Differentiated PC12 Cells
2015 · Chien-Min Lin, Yi-Tzu Lin, et al. · ACS Chemical Neuroscience · 43
Synthesis of N‐Hydroxycinnamides Capped with a Naturally Occurring Moiety as Inhibitors of Histone Deacetylase
2010 · Wei‐Jan Huang, Ching‐Chow Chen, et al. · ChemMedChem · 42
(−)‐Epigallocatechin gallate, the most active polyphenolic catechin in green tea, presynaptically facilitates Ca2+‐dependent glutamate release via activation of protein kinase C in rat cerebral cortex
2007 · Chien‐Wen Chou, Wei‐Jan Huang, et al. · Synapse · 42
Effects of nicotinic acid derivatives on tyrosinase inhibitory and antioxidant activities
2011 · Yin-Shiou Lin, Sheng-Hsuan Chen, et al. · Food Chemistry · 41
Low-Luminance Blue Light-Enhanced Phototoxicity in A2E-Laden RPE Cell Cultures and Rats
2019 · Cheng-Hui Lin, Man-Ru Wu, et al. · International Journal of Molecular Sciences · 38
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Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors
2011 · Wei-Jan Huang, Ching-Chow Chen, et al. · European Journal of Medicinal Chemistry · 37
Cerebellar α6‐subunit‐containing GABAAreceptors: a novel therapeutic target for disrupted prepulse inhibition in neuropsychiatric disorders
2018 · Lih‐Chu Chiou, Hsin‐Jung Lee, et al. · British Journal of Pharmacology · 36
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Works count: 126
Citation count: 2,885
H-index: 33
I10-index: 84
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