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Liqiang Chen
Observed names:
CHEN L,
L Chen,
L. CHEN,
L. Chen
Institution:
University of Minnesota
Observed institutions:
University of Iowa,
University of Minnesota,
University of Minnesota System,
Richard L. Roudebush VA Medical Center,
National Institute of Allergy and Infectious Diseases,
Indiana University School of Medicine,
Brandeis University
show all 7
ORCID:
0000-0002-4229-863X
Observed ORCID:
0000-0002-4229-863X
OpenAlex ID:
A5100768110
A single-amino acid substitution in West Nile virus 2K peptide between NS4A and NS4B confers resistance to lycorine, a flavivirus inhibitor
2008
·
Gang Zou
, Francesc Puig-Basagoiti
, et al.
·
Virology
·
149
PDF
Inhibition of Siderophore Biosynthesis in Mycobacterium tuberculosis with Nucleoside Bisubstrate Analogues: Structure−Activity Relationships of the Nucleobase Domain of 5′-O-[N-(Salicyl)sulfamoyl]adenosine
2008
·
João Neres
, Nicholas P. Labello
, et al.
·
Journal of Medicinal Chemistry
·
128
Discovery of Potent and Selective Sirtuin 2 (SIRT2) Inhibitors Using a Fragment-Based Approach
2014
·
Huaqing Cui
, Zeeshan Kamal
, et al.
·
Journal of Medicinal Chemistry
·
86
Recent development of IMP dehydrogenase inhibitors for the treatment of cancer.
2007
·
Liqiang Chen
, Krzysztof W Pankiewicz
·
PubMed
·
82
Triazole-Linked Inhibitors of Inosine Monophosphate Dehydrogenase from Human and Mycobacterium tuberculosis
2010
·
Liqiang Chen
, Daniel J. Wilson
, et al.
·
Journal of Medicinal Chemistry
·
64
mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress
2016
·
Young Sung Yun
, Kwan Hyun Kim
, et al.
·
Molecular Cell
·
61
PDF
A Novel Sirtuin-3 Inhibitor, LC-0296, Inhibits Cell Survival and Proliferation, and Promotes Apoptosis of Head and Neck Cancer Cells.
2016
·
Turki Y Alhazzazi
, Pachiyappan Kamarajan
, et al.
·
PubMed
·
61
Dual Inhibitors of Inosine Monophosphate Dehydrogenase and Histone Deacetylases for Cancer Treatment
2007
·
Liqiang Chen
, Daniel Wilson
, et al.
·
Journal of Medicinal Chemistry
·
61
Nicotinamide Adenine Dinucleotide Based Therapeutics
2008
·
K. Pankiewicz
, L. Chen
, et al.
·
Current Medicinal Chemistry
·
53
Medicinal Chemistry of Sirtuin Inhibitors
2011
·
L. Chen
·
Current Medicinal Chemistry
·
51
Hydroxamic Acids Block Replication of Hepatitis C Virus
2014
·
Teng Ai
, Yanli Xu
, et al.
·
Journal of Medicinal Chemistry
·
50
Bisubstrate Inhibitors of Severe Acute Respiratory Syndrome Coronavirus-2 Nsp14 Methyltransferase
2022
·
Eunkyung Jung
, Ruben Soto-Acosta
, et al.
·
ACS Medicinal Chemistry Letters
·
47
USP14 is a predictor of recurrence in endometrial cancer and a molecular target for endometrial cancer treatment
2016
·
Rachel Isaksson Vogel
, Tanya Pulver
, et al.
·
Oncotarget
·
44
PDF
Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner
2015
·
N Preyat
, M Rossi
, et al.
·
Cell Death and Differentiation
·
42
Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure
2010
·
Liqiang Chen
, Riccardo Petrelli
, et al.
·
Bioorganic & Medicinal Chemistry
·
41
5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors
2016
·
Teng Ai
, Daniel J. Wilson
, et al.
·
Journal of Medicinal Chemistry
·
39
Multi-Targeted Histone Deacetylase Inhibitors in Cancer Therapy
2012
·
T. Ai
, H. Cui
, et al.
·
Current Medicinal Chemistry
·
39
Benzo[b]thiophene-based histone deacetylase inhibitors
2007
·
David J. Witter
, Sandro Belvedere
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
39
Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation
2023
·
Qi Zhang
, Weichun Tang
, et al.
·
Nature Communications
·
28
Probing binding requirements of NAD kinase with modified substrate (NAD) analogues
2007
·
Laurent Bonnac
, Liqiang Chen
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
24
UNC-45A Is a Novel Microtubule-Associated Protein and Regulator of Paclitaxel Sensitivity in Ovarian Cancer Cells
2018
·
Ashley Mooneyham
, Yoshie Iizuka
, et al.
·
Molecular Cancer Research
·
23
Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: Targeting the pyrophosphate binding sub-domain
2011
·
Krzysztof Felczak
, Liqiang Chen
, et al.
·
Bioorganic & Medicinal Chemistry
·
23
Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues
2009
·
Riccardo Petrelli
, Yuk Yin Sham
, et al.
·
Bioorganic & Medicinal Chemistry
·
23
Probing Binding Requirements of Type I and Type II Isoforms of Inosine Monophosphate Dehydrogenase with Adenine-Modified Nicotinamide Adenine Dinucleotide Analogues
2007
·
Liqiang Chen
, Guangyao Gao
, et al.
·
Journal of Medicinal Chemistry
·
23
Discovery of Irreversible p97 Inhibitors
2019
·
Rui Ding
, Ting Zhang
, et al.
·
Journal of Medicinal Chemistry
·
22
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Works count:
80
Citation count:
1,494
H-index:
23
I10-index:
35
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