Author

Yantao He

Observed names: Y He, Y. He, Yan-Tao He, Yan‐Tao He

Institutions: Purdue University West Lafayette, Indiana Biosciences Research Institute

Observed institutions: Chinese Academy of Sciences, Purdue University West Lafayette, Indiana Biosciences Research Institute, Shanghai Institute of Organic Chemistry, Indiana University Bloomington, Indiana University Indianapolis, Indiana University School of Medicine, Indiana University – Purdue University Indianapolis

ORCID: 0000-0002-2692-0345

Observed ORCID: 0000-0002-2692-0345

OpenAlex ID: A5101497092

Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents

2010 · Bo Zhou, Yantao He, et al. · Proceedings of the National Academy of Sciences · 251

Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2)

2010 · Xian Zhang, Yantao He, et al. · Journal of Medicinal Chemistry · 203

Cutting Edge: The PTPN22 Allelic Variant Associated with Autoimmunity Impairs B Cell Signaling

2009 · Adrian F Arechiga, Tania Habib, et al. · The Journal of Immunology · 199

Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice

2022 · Patrick J. Knerr, Stephanie A. Mowery, et al. · Molecular Metabolism · 155

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Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases

2007 · Xiao Yu, Jin-Peng Sun, et al. · Proceedings of the National Academy of Sciences · 145

Small molecule tools for functional interrogation of protein tyrosine phosphatases

2012 · Rongjun He, Li‐Fan Zeng, et al. · FEBS Journal · 136

Aryl Vinyl Sulfonates and Sulfones as Active Site-Directed and Mechanism-Based Probes for Protein Tyrosine Phosphatases

2008 · Sijiu Liu, Bo Zhou, et al. · Journal of the American Chemical Society · 135

Glucose-dependent insulinotropic polypeptide regulates body weight and food intake via GABAergic neurons in mice

2023 · Arkadiusz Liskiewicz, Ahmed Khalil, et al. · Nature Metabolism · 125

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A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus

2008 · V. Orru, S. J. Tsai, et al. · Human Molecular Genetics · 124

Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo

2015 · W Huang, Z Dong, et al. · Oncogene · 113

Negative regulation of TLR signaling in myeloid cells—implications for autoimmune diseases

2015 · Jessica A. Hamerman, Jessica Pottle, et al. · Immunological Reviews · 112

Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT

2012 · Roberto Negro, Stefania Gobessi, et al. · Blood · 83

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Discovery and Evaluation of Novel Inhibitors of Mycobacterium Protein Tyrosine Phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic Acid Scaffold

2013 · Yantao He, Jie Xu, et al. · Journal of Medicinal Chemistry · 77

A Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated with Autoimmune Diseases

2013 · Yantao He, Sijiu Liu, et al. · Journal of Medicinal Chemistry · 69

Negative Regulation of Stat3 by Activating PTPN11 Mutants Contributes to the Pathogenesis of Noonan Syndrome and Juvenile Myelomonocytic Leukemia

2009 · Wenjun Zhang, Rebecca J. Chan, et al. · Journal of Biological Chemistry · 63

Discovery of a Novel Series of Inhibitors of Lymphoid Tyrosine Phosphatase with Activity in Human T Cells

2011 · Stephanie M. Stanford, Divya Krishnamurthy, et al. · Journal of Medicinal Chemistry · 58

Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors

2015 · Rongjun He, Zhi-Hong Yu, et al. · ACS Medicinal Chemistry Letters · 57

The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo

2012 · S C Nabinger, X J Li, et al. · Leukemia · 57

Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT

2012 · Raghuveer Singh Mali, Peilin Ma, et al. · Blood · 57

GLP-1 and GIP agonism has no direct actions in human hepatocytes or hepatic stellate cells

2024 · Natália da Silva Lima, Alba Cabaleiro, et al. · Cellular and Molecular Life Sciences · 53

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Mycobacterial Protein Tyrosine Phosphatases A and B Inhibitors Augment the Bactericidal Activity of the Standard Anti-tuberculosis Regimen

2015 · Noton K. Dutta, Rongjun He, et al. · ACS Infectious Diseases · 45

Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors

2011 · Yantao He, Li-Fan Zeng, et al. · Bioorganic & Medicinal Chemistry · 35

Derivatives of Salicylic Acid as Inhibitors of YopH in Yersinia pestis

2010 · Zunnan Huang, Yantao He, et al. · Chemical Biology & Drug Design · 29

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A Facile Hydroxyindole Carboxylic Acid Based Focused Library Approach for Potent and Selective Inhibitors of Mycobacterium Protein Tyrosine Phosphatase B

2013 · Li‐Fan Zeng, Jie Xu, et al. · ChemMedChem · 24

Organocatalytic multicomponent reaction for the acquisition of a selective inhibitor of mPTPB, a virulence factor of tuberculosis

2013 · Rongjun He, Li-Fan Zeng, et al. · Chemical Communications · 23

Works count: 43

Citation count: 2,555

H-index: 24

I10-index: 31