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Yaofeng Cheng

In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development
2013 · K L R Brouwer, D Keppler, et al. · Clinical Pharmacology & Therapeutics · 273
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Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species
2016 · Hong Shen, Jun Dai, et al. · Journal of Pharmacology and Experimental Therapeutics · 117
Expression of Organic Anion Transporter 2 in the Human Kidney and Its Potential Role in the Tubular Secretion of Guanine-Containing Antiviral Drugs
2011 · Yaofeng Cheng, Arpine Vapurcuyan, et al. · Drug Metabolism and Disposition · 85
Small molecule splicing modifiers with systemic HTT-lowering activity
2021 · Anuradha Bhattacharyya, Christopher R. Trotta, et al. · Nature Communications · 81
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Reprogrammed mesenchymal stem cells derived from iPSCs promote bone repair in steroid-associated osteonecrosis of the femoral head
2021 · Meiling Zhou, Jiaoya Xi, et al. · Stem Cell Research & Therapy · 72
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In vitro model systems to investigate bile salt export pump (BSEP) activity and drug interactions: A review
2015 · Yaofeng Cheng, Thomas F. Woolf, et al. · Chemico-Biological Interactions · 36
Involvement of Drug Transporters in Organ Toxicity: The Fundamental Basis of Drug Discovery and Development
2016 · Yaofeng Cheng, Ayman El-Kattan, et al. · Chemical Research in Toxicology · 26
Characterization of the Disposition and Toxicokinetics of N-Butylpyridinium Chloride in Male F-344 Rats and Female B6C3F1 Mice and Its Transport by Organic Cation Transporter 2
2009 · Y. Cheng, S.H. Wright, et al. · Drug Metabolism and Disposition · 26
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Functional significance of conserved cysteines in the human organic cation transporter 2
2012 · Ryan M. Pelis, Yodying Dangprapai, et al. · American Journal of Physiology-Renal Physiology · 20
Biliary excretion of pravastatin and taurocholate in rats with bile salt export pump (Bsep) impairment
2016 · Yaofeng Cheng, Chris Freeden, et al. · Biopharmaceutics & Drug Disposition · 18
Characterization of the Inhibitory Effects of N-Butylpyridinium Chloride and Structurally Related Ionic Liquids on Organic Cation Transporters 1/2 and Human Toxic Extrusion Transporters 1/2-K In Vitro and In Vivo
2011 · Yaofeng Cheng, Lucy J. Martinez-Guerrero, et al. · Drug Metabolism and Disposition · 14
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Clinical significance of CYP2C19 polymorphisms on the metabolism and pharmacokinetics of 11β‐hydroxysteroid dehydrogenase type‐1 inhibitor BMS‐823778
2017 · Yaofeng Cheng, Lifei Wang, et al. · British Journal of Clinical Pharmacology · 13
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Effects of Dose and Route on the Disposition and Kinetics of 1-Butyl-1-methylpyrrolidinium Chloride in Male F-344 Rats
2009 · G.A. Knudsen, Y. Cheng, et al. · Drug Metabolism and Disposition · 12
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Application of a PBPK model to elucidate the changes of systemic and liver exposures for rosuvastatin, carotegrast, and bromfenac followed by OATP inhibition in monkeys
2021 · Yaofeng Cheng, Xiaomin Liang, et al. · Clinical and Translational Science · 10
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[Effect of Spatholobus suberectus on the bone marrow cells and related cytokines of mice].
2004 · Dong-hui Chen, Xia Luo, et al. · PubMed · 10
Abstract 3318: GFH375 (VS-7375): An oral, selective KRAS G12D (ON/OFF) inhibitor with potent anti-tumor efficacy
2024 · Feng Yan, Tao Jiang, et al. · Cancer Research · 9
Bile Salt Homeostasis in Normal and Bsep Gene Knockout Rats with Single and Repeated Doses of Troglitazone
2017 · Yaofeng Cheng, Shenjue Chen, et al. · Journal of Pharmacology and Experimental Therapeutics · 9
Abstract C026: Initial safety, pharmacokinetics, and recommended Phase 2 dose from RAMP 203: A Phase 1/2 study of Avutometinib + Sotorasib in KRAS G12C Mutant Non-Small Cell Lung Cancer
2023 · Mark M Awad, Jerome Goldschmidt, et al. · Molecular Cancer Therapeutics · 8
[The influence of Bazhen decoction on hematopoietic modulator in anaemic mice].
2004 · Ze Chun, Xia Luo, et al. · PubMed · 6
Transporters in Drug Discovery and Development
2019 · Yaofeng Cheng, Yurong Lai · CRC Press eBooks · 1
Exposure-response analysis for avutometinib in combination with defactinib in low-grade serous ovarian cancer
2026 · Yaofeng Cheng, Sarath Nagothu, et al. · Gynecologic Oncology
Avutometinib + Defactinib in Recurrent Low-grade Serous Ovarian Cancer (lgsoc): a Phase 2 Study in Japanese Patients
2025 · Takafumi Kuroda, Muneaki Shimada, et al. · International Journal of Gynecological Cancer
Abstract C003: RAMP 205: A phase 1b/2a study of gemcitabine, nab-paclitaxel, avutometinib, and defactinib in untreated metastatic pancreatic ductal adenocarcinoma
2024 · Kian-Haut Lim, Manuel Hidalgo, et al. · Cancer Research
I01 Orally bioavailable small molecule splicing modifiers with systemic and even htt-lowering activity in vitro and in vivo
2021 · Anuradha Bhattacharyya, Kerstin Effenberger, et al. · Journal of Neurology Neurosurgery & Psychiatry
Effects of troglitazone on bile acid disposition in Bsep KO rats
2017 · Yaofeng Cheng, Shenjue Chen, et al. · The FASEB Journal
Works count: 30
Citation count: 846
H-index: 12
I10-index: 15
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