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Yi Cui

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
2015 · Margaret A. Phillips, Julie Lotharius, et al. · Science Translational Medicine · 394
Simulation of multiple ion channel block provides improved early prediction of compounds’ clinical torsadogenic risk
2011 · Gary R. Mirams, Yi Cui, et al. · Cardiovascular Research · 321
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Comparison of Electrophysiological Data From Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes to Functional Preclinical Safety Assays
2013 · Kate Harris, Mike Aylott, et al. · Toxicological Sciences · 233
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Application of cardiac electrophysiology simulations to pro‐arrhythmic safety testing
2012 · Gary R Mirams, Mark R Davies, et al. · British Journal of Pharmacology · 98
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Prediction of Thorough QT study results using action potential simulations based on ion channel screens
2014 · Gary R. Mirams, Mark R. Davies, et al. · Journal of Pharmacological and Toxicological Methods · 93
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Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment
2013 · Ryan C. Elkins, Mark R. Davies, et al. · Journal of Pharmacological and Toxicological Methods · 90
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A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor
2020 · Toby M. Maher, Juliet K. Simpson, et al. · Respiratory Research · 75
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Sinusoidal Voltage Protocols for Rapid Characterisation of Ion Channel Kinetics
2018 · Kylie A. Beattie, Adam P. Hill, et al. · The Journal of Physiology · 74
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Evaluation of an in silico cardiac safety assay: Using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge
2013 · Kylie A. Beattie, Chris Luscombe, et al. · Journal of Pharmacological and Toxicological Methods · 71
An Antagonist of cADP-ribose Inhibits Arrhythmogenic Oscillations of Intracellular Ca2+ In Heart Cells
1999 · Stevan Rakovic, Yi Cui, et al. · Journal of Biological Chemistry · 55
Translation of flecainide- and mexiletine-induced cardiac sodium channel inhibition and ventricular conduction slowing from nonclinical models to clinical
2010 · B.M. Heath, Y. Cui, et al. · Journal of Pharmacological and Toxicological Methods · 47
Recommendations for Safety Pharmacology Evaluations of Oligonucleotide-Based Therapeutics
2014 · Cindy L. Berman, Keri Cannon, et al. · Nucleic Acid Therapeutics · 44
Depletion of LAG‐3 + T Cells Translated to Pharmacology and Improvement in Psoriasis Disease Activity: A Phase I Randomized Study of mAb GSK2831781
2020 · Joanne Ellis, Daniel J.B. Marks, et al. · Clinical Pharmacology & Therapeutics · 37
Functional Expression of Inward Rectifier Potassium Channels in Cultured Human Pulmonary Smooth Muscle Cells: Evidence for a Major Role of Kir2.4 Subunits
2006 · Brian P. Tennant, Yi Cui, et al. · The Journal of Membrane Biology · 37
Cyclic ADP-ribose and the regulation of calcium-induced calcium release in eggs and cardiac myocytes
1998 · Antony Galione, Yi Cui, et al. · Cell Biochemistry and Biophysics · 29
Chemotactic Migration Triggers IL-8 Generation in Neutrophilic Leukocytes
1999 · Rafat A Siddiqui, Luke P Akard, et al. · The Journal of Immunology · 24
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Effects of tumor necrosis factor-alpha on calcium movement in rat ventricular myocytes.
2003 · Xiao-Qiang Li, Ming-Gao Zhao, et al. · PubMed · 23
Relationship between Pharmacokinetics and Pharmacodynamic Responses in Healthy Smokers Informs a Once-Daily Dosing Regimen for Nemiralisib
2019 · M Begg, R Wilson, et al. · Journal of Pharmacology and Experimental Therapeutics · 18
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Assessment of the safety, pharmacokinetics and pharmacodynamics of GSK3335065, an inhibitor of kynurenine monooxygenase, in a randomised placebo‐controlled first‐in‐human study in healthy volunteers
2021 · Disala Fernando, Richard Dimelow, et al. · British Journal of Clinical Pharmacology · 7
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A randomized study of the safety and pharmacokinetics of GSK3358699, a mononuclear myeloid‐targeted bromodomain and extra‐terminal domain inhibitor
2021 · Jack A. Brown, Joanne Bal, et al. · British Journal of Clinical Pharmacology · 5
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The metabolite ILA of Akkermansia muciniphila improves AP-related intestinal injury by targeting and inhibiting CASP3 activity
2025 · Peiyu Li, Jiuliang Yu, et al. · Frontiers in Microbiology · 3
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Inhibitory effects of serotonin on transient outward potassium current in rat ventricular myocytes.
2002 · Ming-Gao Zhao, Qi-Bing Mei, et al. · PubMed · 3
06 Possible role of the ultra-rapid delayed rectifier potassium current (IKur) in action potential repolarisation in rabbit heart
2010 · Y. Cui, C. Wilson, et al. · Heart · 2
Late Breaking Abstract - Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry demonstrates inhaled drug deposition in transbronchial cryobiopsy samples of patients with Interstitial Lung Disease (ILD)
2019 · Theresia Mikolasch, Peter S. Marshall, et al. · European Respiratory Journal · 1
Docosahexaenoic acid, folic acid, and phosphatidylserine co-intervention alleviate cognitive impairment in D -galactose-induced aged mice
2025 · Yingying Lin, Yi Cui, et al. · Food Science and Human Wellness
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Works count: 41
Citation count: 1,784
H-index: 18
I10-index: 18
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