Get started
Author

Stefano Fumagalli

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
2004 · Sung Hee Um, Francesca Frigerio, et al. · Nature · 1,674
Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k
1997 · Harold B.J. Jefferies, Stefano Fumagalli, et al. · The EMBO Journal · 934
PDF
S6K1 −/− / S6K2 −/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway
2004 · Mario Pende, Sung Hee Um, et al. · Molecular and Cellular Biology · 742
Disruption of the p70s6k/p85s6k gene reveals a small mouse phenotype and a new functional S6 kinase
1998 · Hiroshi Shima, Mario Pende, et al. · The EMBO Journal · 636
The mTOR Inhibitor RAD001 Sensitizes Tumor Cells to DNA-Damaged Induced Apoptosis through Inhibition of p21 Translation
2005 · Iwan Beuvink, Anne Boulay, et al. · Cell · 486
PDF
A target for Src in mitosis
1994 · Stefano Fumagalli, Nicholas F. Totty, et al. · Nature · 365
Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction
2009 · Stefano Fumagalli, Alessandro Di Cara, et al. · Nature Cell Biology · 322
Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation
1999 · Patrick B Dennis, Stefano Fumagalli, et al. · Current Opinion in Genetics & Development · 275
Csk inhibition of c‐Src activity requires both the SH2 and SH3 domains of Src.
1993 · G. Superti‐Furga, S. Fumagalli, et al. · The EMBO Journal · 263
PDF
Requirement for Src Family Protein Tyrosine Kinases in G 2 for Fibroblast Cell Division
1995 · Serge Roche, Stefano Fumagalli, et al. · Science · 249
Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint
2012 · Stefano Fumagalli, Vasily V. Ivanenkov, et al. · Genes & Development · 215
PDF
Loss of Tumor Suppressor RPL5/RPL11 Does Not Induce Cell Cycle Arrest but Impedes Proliferation Due to Reduced Ribosome Content and Translation Capacity
2013 · Teng Teng, Carol A. Mercer, et al. · Molecular and Cellular Biology · 98
PDF
The Role of p53 in Ribosomopathies
2011 · Stefano Fumagalli, George Thomas · Seminars in Hematology · 83
Somatic genetic rescue of a germline ribosome assembly defect
2021 · Shengjiang Tan, Laëtitia Kermasson, et al. · Nature Communications · 78
PDF
EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome
2019 · Shengjiang Tan, Laëtitia Kermasson, et al. · Blood · 78
PDF
A homoeostatic switch causing glycerol-3-phosphate and phosphoethanolamine accumulation triggers senescence by rewiring lipid metabolism
2024 · Khaled Tighanimine, José Américo Nabuco Leva Ferreira Freitas, et al. · Nature Metabolism · 74
PDF
The Human p62 cDNA Encodes Sam68 and Not the RasGAP-Associated p62 Protein
1996 · Peter Lock, Stefano Fumagalli, et al. · Cell · 72
PDF
The Src family of protein tyrosine kinases: regulation and functions
1993 · Sara A. Courtneidge, Stefano Fumagalli, et al. · Development · 67
Expression of the c-ski proto-oncogene in human melanoma cell lines
1993 · S. Fumagalli, L. Doneda, et al. · Melanoma Research · 67
Insulin Regulation of Insulin-like Growth Factor-binding Protein-1 Gene Expression Is Dependent on the Mammalian Target of Rapamycin, but Independent of Ribosomal S6 Kinase Activity
2002 · Satish Patel, Pamela A. Lochhead, et al. · Journal of Biological Chemistry · 44
PDF
Cot/tpl2-MKK1/2-Erk1/2 controls mTORC1-mediated mRNA translation in Toll-like receptor–activated macrophages
2012 · Marta López-Pelaéz, Stefano Fumagalli, et al. · Molecular Biology of the Cell · 41
PDF
A mitotic function for Src?
1994 · Sara A. Courtneidge, Stefano Fumagalli · Trends in Cell Biology · 38
Molecular Interaction between Limb Deformity Proteins (Formins) and Src Family Kinases
1996 · Peter Uetz, Stefano Fumagalli, et al. · Journal of Biological Chemistry · 35
PDF
S6 kinase 1 at the central node of cell size and ageing
2022 · Stefano Fumagalli, Mario Pende · Frontiers in Cell and Developmental Biology · 25
PDF
23 S6 Phosphorylation and Signal Transduction
2000 · Stefano Fumagalli, George Thomas · Cold Spring Harbor Monograph Archive · 23
Works count: 44
Citation count: 7,019
H-index: 24
I10-index: 26
Year
Topic
Type