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Rajesh Kumar

Extending the application of biocatalysis to meet the challenges of drug development
2018 · Paul N. Devine, Roger M. Howard, et al. · Nature Reviews Chemistry · 443
Multifunctional biocatalyst for conjugate reduction and reductive amination
2022 · Thomas W. Thorpe, James R. Marshall, et al. · Nature · 150
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Biocatalytic reductive amination from discovery to commercial manufacturing applied to abrocitinib JAK1 inhibitor
2021 · Rajesh Kumar, Michael J. Karmilowicz, et al. · Nature Catalysis · 147
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Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination
2017 · Scott P. France, Roger M. Howard, et al. · ChemCatChem · 110
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Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines
2017 · Scott P. France, Godwin A. Aleku, et al. · Angewandte Chemie International Edition · 97
A Computational Approach to Enzyme Design: Predicting ω-Aminotransferase Catalytic Activity Using Docking and MM-GBSA Scoring
2014 · Sarah Sirin, Rajesh Kumar, et al. · Journal of Chemical Information and Modeling · 95
One-Pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N-Heterocycles
2019 · Thomas W. Thorpe, Scott P. France, et al. · Journal of the American Chemical Society · 64
Pseudomonas stutzeri lipase: a useful biocatalyst for aminolysis reactions
2011 · S. van Pelt, R. L. M. Teeuwen, et al. · Green Chemistry · 60
Editorial overview: Biocatalysis and biotransformation: The golden age of biocatalysis
2018 · Nicholas J Turner, Rajesh Kumar · Current Opinion in Chemical Biology · 41
Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor
2021 · Shengquan Duan, Daniel W. Widlicka, et al. · Organic Process Research & Development · 38
Developing an Asymmetric Transfer Hydrogenation Process for ( S )-5-Fluoro-3-methylisobenzofuran-1(3 H )-one, a Key Intermediate to Lorlatinib
2017 · Shengquan Duan, Bryan Li, et al. · Organic Process Research & Development · 37
Development of a Nitrene-Type Rearrangement for the Commercial Route of the JAK1 Inhibitor Abrocitinib
2020 · Christina G. Connor, Jacob C. DeForest, et al. · Organic Process Research & Development · 29
Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor
2023 · Jeremy Steflik, Amelia Gilio, et al. · ACS Catalysis · 25
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Application of Flow and Biocatalytic Transaminase Technology for the Synthesis of a 1-Oxa-8-azaspiro[4.5]decan-3-amine
2021 · Jeffrey T. Kohrt, Peter H. Dorff, et al. · Organic Process Research & Development · 16
Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines
2017 · Scott P. France, Godwin A. Aleku, et al. · Angewandte Chemie · 15
Role and Application of Biocatalysts in Cancer Drug Discovery
2023 · Sounok Sengupta, Prathama Das, et al. · Catalysts · 12
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Development of a Practical and Efficient Synthesis of Chloromethyl 2-Ethoxy-2-methylpropanoate
2010 · John A. Ragan, Nathan D. Ide, et al. · Organic Process Research & Development · 8
Synthesis of Enantiopure Fluoropiperidines via Biocatalytic Desymmetrization and Flow Photochemical Decarboxylative Fluorination
2024 · Caroline A. Blakemore, John M. Humphrey, et al. · Organic Process Research & Development · 7
Development of Chemoenzymatic Processes
2016 · Rajesh Kumar, Carlos Martinez, et al. · Wiley eBooks · 4
Expanding the Biocatalysis Toolbox
2021 · Rajesh Kumar, Carlos A. Martinez, et al. · Methods in pharmacology and toxicology · 3
Novel drug delivery system in the management of myasthenia gravis
2024 · Mahendra Yadav, Rajesh Kumar, et al. · Elsevier eBooks · 1
Early Process Development of Two Vanin-1 Inhibitors: Solid Form Challenges and Control of Ambident Reactivity
2024 · Christophe Allais, Agustin Casimiro-Garcia, et al. · Organic Process Research & Development · 1
Reporting of Adverse Drug Reaction by Pharmacist in Pharmacovigilance Programme of India: Perspective
2023 · I. Kaur, V. Kalaiselvan, et al. · Book Publisher International (a part of SCIENCEDOMAIN International) · 1
Understanding Incomplete Metabolism
2025 · Anjna Sharma, Hitesh Chopra, et al. · BENTHAM SCIENCE PUBLISHERS eBooks
Porous silicon nanoparticles in codelivery of drugs for improved cellular uptake and targeted drug delivery
2025 · Rajesh Kumar, Pankaj Kalia, et al. · Elsevier eBooks
Works count: 27
Citation count: 1,404
H-index: 15
I10-index: 16
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