Author

Miguel Guerrero

Institution: Scripps Research Institute

Observed institution: Scripps Research Institute

ORCID: 0000-0001-6137-8072

Observed ORCID: 0000-0001-6137-8072

OpenAlex ID: A5102014119

Full Pharmacological Efficacy of a Novel S1P1 Agonist That Does Not Require S1P-Like Headgroup Interactions

2008 · Pedro J. Gonzalez-Cabrera, Euijung Jo, et al. · Molecular Pharmacology · 127

Sphingosine 1-Phosphate Receptor 1 (S1P1) Upregulation and Amelioration of Experimental Autoimmune Encephalomyelitis by an S1P1 Antagonist

2012 · Stuart M. Cahalan, Pedro J. Gonzalez-Cabrera, et al. · Molecular Pharmacology · 34

Optimization and characterization of an opioid kappa receptor (OPRK1) antagonist

2014 · Miguel Guerrero, Mariagela Urbano, et al. · Europe PMC (PubMed Central) · 4

Figure 4, Flow chart describing Maybridge screening results

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Table 7, Hepatic microsome stability of ML350

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Table 3, Targets that exhibit ≥ 50% inhibition by ML350 in CEREP screen

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Table 4, Levels of ML350 in plasma and brain of mice 30 and 120 minutes after IP administration

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Figure 8, Results of Tail Flick assay to determine the reversibility of the analgesic effect of ML350

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Figure 5, Compound identified from Maybridge library; CID 2796048

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Figure 7, ML350 has high passive membrane permeability, similar to positive controls propanolol and antipirine

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Figure 2, Stability of ML350 (CYM50202) in PBS

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Table 9, Prior Art OPRK Antagonist Compounds

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Table 6, Binding of ML350 to human, mouse, and rat plasma proteins

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Table 5, Inhibition of human cytochrome P450 subtypes 1A2, 2C9, 2D6, and 3A4 by ML350

2014 · Miguel Guerrero, Mariagela Urbano, et al.

Table 4, SAR Table for S1P4 Receptor Agonist Probe Optimization. Fragment point of attachment of is indicated with an *

2011 · Miguel Guerrero, Mariangela Urbano, et al.

Table 1, Published S1P4 Receptor Agonists

2011 · Miguel Guerrero, Mariangela Urbano, et al.

Table 3, Specificity of selected S1P4 receptor agonist compounds against S1P1, S1P2, S1P3, and S1P5 receptors

2011 · Miguel Guerrero, Mariangela Urbano, et al.

Figure 3, Stability of Probe ML178 in PBS

2011 · Miguel Guerrero, Mariangela Urbano, et al.

Table 3, SAR Table for S1P4 receptor antagonist probe optimization

2010 · Michael B. A. Oldstone, Peter Hodder, et al.

Table 4, SAR Table

2010 · Miguel Guerrero, Mariangela Urbano, et al.

Table 2, Overview of PubChem assays for GPR7 antagonist project

2010 · Miguel Guerrero, Mariangela Urbano, et al.

Figure 4, GPR7 antagonist HTS overview

2010 · Miguel Guerrero, Mariangela Urbano, et al.

Table 8, Targets that exhibited ≥ 50% inhibiton in Ricerca screening

2010 · Miguel Guerrero, Mariangela Urbano, et al.

Table 6, Selectivity of selected S1P4 receptor agonist compounds against S1P1, S1P2, S1P3, and S1P5

2010 · Miguel Guerrero, Mariangela Urbano, et al.

Table 6, Targets that exhibited ≥50% in Ricerca screening

2010 · Miguel Guerrero, Mariangela Urbano, et al.

Works count: 28

Citation count: 165

H-index: 3

I10-index: 2