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Zhen Shi

Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide
2017 · Zhen Shi, Kotaro Fujii, et al. · Molecular Cell · 679
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Differential Requirements for eIF4E Dose in Normal Development and Cancer
2015 · Morgan L. Truitt, Crystal S. Conn, et al. · Cell · 384
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Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRAS G12C Mutation
2023 · Adrian Sacher, Patricia LoRusso, et al. · New England Journal of Medicine · 367
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Translation control of the immune checkpoint in cancer and its therapeutic targeting
2019 · Yichen Xu, Mauro Poggio, et al. · Nature Medicine · 267
Translating the Genome in Time and Space: Specialized Ribosomes, RNA Regulons, and RNA-Binding Proteins
2015 · Zhen Shi, Maria Barna · Annual Review of Cell and Developmental Biology · 219
Comprehensive pan-cancer genomic landscape of KRAS altered cancers and real-world outcomes in solid tumors
2022 · Jessica K. Lee, Smruthy Sivakumar, et al. · npj Precision Oncology · 213
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FAIRLANE, a double-blind placebo-controlled randomized phase II trial of neoadjuvant ipatasertib plus paclitaxel for early triple-negative breast cancer
2019 · M. Oliveira, C. Saura, et al. · Annals of Oncology · 156
Divarasib plus cetuximab in KRAS G12C-positive colorectal cancer: a phase 1b trial
2023 · Jayesh Desai, Guzman Alonso, et al. · Nature Medicine · 154
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SRSF1 and SRSF9 RNA binding proteins promote Wnt signalling‐mediated tumorigenesis by enhancing β‐catenin biosynthesis
2013 · Yu Fu, Binlu Huang, et al. · EMBO Molecular Medicine · 118
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Pervasive translational regulation of the cell signalling circuitry underlies mammalian development
2017 · Kotaro Fujii, Zhen Shi, et al. · Nature Communications · 78
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Repression of Germline RNAi Pathways in Somatic Cells by Retinoblastoma Pathway Chromatin Complexes
2012 · Xiaoyun Wu, Zhen Shi, et al. · PLoS Genetics · 69
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High-throughput sequencing reveals extraordinary fluidity of miRNA, piRNA, and siRNA pathways in nematodes
2013 · Zhen Shi, Taiowa A. Montgomery, et al. · Genome Research · 65
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A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production
2022 · Naomi R. Genuth, Zhen Shi, et al. · Nature Communications · 64
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Functional Mapping of AKT Signaling and Biomarkers of Response from the FAIRLANE Trial of Neoadjuvant Ipatasertib plus Paclitaxel for Triple-Negative Breast Cancer
2021 · Zhen Shi, Julia Wulfkuhle, et al. · Clinical Cancer Research · 55
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Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans
2013 · Sylvia E.J. Fischer, Qi Pan, et al. · Genes & Development · 43
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Overall survival in patients with advanced non-small cell lung cancer with KRAS G12C mutation with or without STK11 and/or KEAP1 mutations in a real-world setting
2023 · Cristina Julian, Navdeep Pal, et al. · BMC Cancer · 36
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Final Overall Survival and Molecular Data Associated with Clinical Outcomes in Patients Receiving Ipatasertib and Abiraterone in the Phase 3 IPATential150 Trial
2025 · Johann S. de Bono, Meng He, et al. · European Urology · 34
A saturation mutagenesis screen uncovers resistant and sensitizing secondary KRAS mutations to clinical KRAS G12C inhibitors
2022 · Siyu Feng, Marinella G. Callow, et al. · Proceedings of the National Academy of Sciences · 33
Circulating Tumor DNA Dynamics Reveal KRAS G12C Mutation Heterogeneity and Response to Treatment with the KRAS G12C Inhibitor Divarasib in Solid Tumors
2024 · Yoonha Choi, Neekesh V. Dharia, et al. · Clinical Cancer Research · 29
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans
2012 · Zhen Shi, Gary Ruvkun · Proceedings of the National Academy of Sciences · 29
PI3K/AKT pathway biomarkers analysis from the phase III IPATential150 trial of ipatasertib plus abiraterone in metastatic castration-resistant prostate cancer.
2021 · Johann S. De Bono, Christopher Sweeney, et al. · Journal of Clinical Oncology · 25
OA03.04 Phase I A Study to Evaluate GDC-6036 Monotherapy in Patients with Non-small Cell Lung Cancer (NSCLC) with KRAS G12C Mutation
2022 · A. Sacher, M.R. Patel, et al. · Journal of Thoracic Oncology · 22
Biomarker analysis of the phase III IPATential150 trial of first-line ipatasertib (Ipat) plus abiraterone (Abi) in metastatic castration-resistant prostate cancer (mCRPC).
2020 · Zhen Shi, Christopher Sweeney, et al. · Journal of Clinical Oncology · 22
Assessment of KRAS G12C Target Engagement by a Covalent Inhibitor in Tumor Biopsies Using an Ultra-Sensitive Immunoaffinity 2D-LC–MS/MS Approach
2022 · Lingyao Meng, Emily W. Chan, et al. · Analytical Chemistry · 16
SPEX: A modular end-to-end platform for high-plex tissue spatial omics analysis
2025 · Xiao Li, Ximo Pechuan-Jorge, et al. · GigaScience · 14
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Works count: 80
Citation count: 3,249
H-index: 22
I10-index: 28
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