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Nadine Becker
Observed name:
Becker Nadine
Institution:
Nanion (Germany)
Observed institution:
Nanion (Germany)
ORCID:
0009-0009-0372-5991
Observed ORCID:
0009-0009-0372-5991
OpenAlex ID:
A5102234443
Improved PIEZO1 agonism through 4‐benzoic acid modification of Yoda1
2022
·
Gregory Parsonage
, Kevin Cuthbertson
, et al.
·
British Journal of Pharmacology
·
70
PDF
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes
2022
·
Fitzwilliam Seibertz
, Markus Rapedius
, et al.
·
Communications Biology
·
68
PDF
Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module
2015
·
Alison Obergrussberger
, Andrea Brüggemann
, et al.
·
SLAS TECHNOLOGY
·
58
An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery
2018
·
Alison Obergrussberger
, Tom A. Goetze
, et al.
·
Expert Opinion on Drug Discovery
·
54
A novel gain-of-function mutation of Piezo1 is functionally affirmed in red blood cells by high-throughput patch clamp
2018
·
Maria G. Rotordam
, Elisa Fermo
, et al.
·
Haematologica
·
53
PDF
A Hybrid Model for Safety Pharmacology on an Automated Patch Clamp Platform: Using Dynamic Clamp to Join iPSC-Derived Cardiomyocytes and Simulations of Ik1 Ion Channels in Real-Time
2018
·
Birgit Goversen
, Nadine Becker
, et al.
·
Frontiers in Physiology
·
53
Minimized cell usage for stem cell-derived and primary cells on an automated patch clamp system
2013
·
Nadine Becker
, Sonja Stoelzle
, et al.
·
Journal of Pharmacological and Toxicological Methods
·
51
Novel screening techniques for ion channel targeting drugs
2015
·
Alison Obergrussberger
, Sonja Stölzle-Feix
, et al.
·
Channels
·
50
A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm
2020
·
Bradley J. Ridder
, Derek J. Leishman
, et al.
·
Toxicology and Applied Pharmacology
·
48
Minimized Cell Usage for Stem Cell-Derived and Primary Cells on an Automated Patch Clamp System
2014
·
Nadine Becker
, Sonja Stoelzle-Feix
, et al.
·
Biophysical Journal
·
38
PDF
Missense mutations in PIEZO1, which encodes the Piezo1 mechanosensor protein, define Er red blood cell antigens
2022
·
Vanja Karamatic Crew
, Louise A. Tilley
, et al.
·
Blood
·
36
PDF
Identification of Drug–Drug InteractionsIn Vitro: A Case Study Evaluating the Effects of Sofosbuvir and Amiodarone on hiPSC-Derived Cardiomyocytes
2016
·
Daniel C. Millard
, Christopher J. Strock
, et al.
·
Toxicological Sciences
·
34
Safety pharmacology studies using EFP and impedance
2016
·
Alison Obergrussberger
, Krisztina Juhasz
, et al.
·
Journal of Pharmacological and Toxicological Methods
·
34
Mechanisms of acquired long QT syndrome in patients with propionic academia
2016
·
Ilona Bodi
, Sarah C. Grünert
, et al.
·
Heart Rhythm
·
32
Automated Patch Clamp Analysis of nAChα7 and NaV1.7 Channels
2014
·
Alison Obergrussberger
, Claudia Haarmann
, et al.
·
Current Protocols in Pharmacology
·
26
Automated Dynamic Clamp for Simulation of IK1 in Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes in Real Time Using Patchliner Dynamite8
2019
·
Nadine Becker
, András Horváth
, et al.
·
Current Protocols in Pharmacology
·
24
A general procedure to select calibration drugs for lab-specific validation and calibration of proarrhythmia risk prediction models: An illustrative example using the CiPA model
2020
·
Xiaomei Han
, Mohammadreza Samieegohar
, et al.
·
Journal of Pharmacological and Toxicological Methods
·
21
The Gárdos Channel and Piezo1 Revisited: Comparison between Reticulocytes and Mature Red Blood Cells
2024
·
Polina Petkova-Kirova
, Nicoletta Murciano
, et al.
·
International Journal of Molecular Sciences
·
19
PDF
Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment
2020
·
Nina Brinkwirth
, Kiyoshi Takasuna
, et al.
·
Journal of Pharmacological and Toxicological Methods
·
18
A high-throughput electrophysiology assay to study the response of PIEZO1 to mechanical stimulation
2023
·
Nicoletta Murciano
, Maria Giustina Rotordam
, et al.
·
The Journal of General Physiology
·
17
PDF
Altered Ca2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis
2021
·
Ralfs Buks
, Tracy Dagher
, et al.
·
Cells
·
14
PDF
Lysosomal Ion Channels and Transporters: Recent Findings, Therapeutic Potential, and Technical Approaches
2025
·
Artem Kondratskyi
, Andre Bazzone
, et al.
·
Bioelectricity
·
13
Transient receptor potential channel vanilloid type 2 in red cells of cannabis consumer
2022
·
Daniel Flormann
, Min Qiao
, et al.
·
American Journal of Hematology
·
12
PDF
Automated Patch Clamp Recordings of Human Stem Cell-Derived Cardiomyocytes
2016
·
Alison Obergrussberger
, Claudia Haarmann
, et al.
·
Methods in pharmacology and toxicology
·
12
The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation
2024
·
Elena Budusan
, Colton D. Payne
, et al.
·
Biochemical Pharmacology
·
9
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Works count:
73
Citation count:
916
H-index:
18
I10-index:
24
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