Get started
Author

Can Gan

Liver diseases: epidemiology, causes, trends and predictions
2025 · Can Gan, Yuan Yuan, et al. · Signal Transduction and Targeted Therapy · 313
PDF
STING mediates hepatocyte pyroptosis in liver fibrosis by Epigenetically activating the NLRP3 inflammasome
2023 · Yang Xiao, Chong Zhao, et al. · Redox Biology · 181
Mechanotransduction-induced glycolysis epigenetically regulates a CXCL1-dominant angiocrine signaling program in liver sinusoidal endothelial cells in vitro and in vivo
2022 · Thomas Greuter, Usman Yaqoob, et al. · Journal of Hepatology · 91
Inflammasomes and Pyroptosis of Liver Cells in Liver Fibrosis
2022 · Can Gan, Qiuyu Cai, et al. · Frontiers in Immunology · 90
PDF
PD-L1 promotes myofibroblastic activation of hepatic stellate cells by distinct mechanisms selective for TGF-β receptor I versus II
2022 · Liankang Sun, Yuanguo Wang, et al. · Cell Reports · 55
PDF
MASLD development: From molecular pathogenesis toward therapeutic strategies
2025 · Zhu Yang, Jiahui Zhao, et al. · Chinese Medical Journal · 43
Mechanism and Therapeutic Opportunities of Histone Modifications in Chronic Liver Disease
2021 · Qiuyu Cai, Can Gan, et al. · Frontiers in Pharmacology · 30
PDF
Efficacy and safety of pancreatic enzyme replacement therapy on exocrine pancreatic insufficiency: a meta-analysis
2017 · Can Gan, Yan-Hua Chen, et al. · Oncotarget · 28
PDF
Risk factors for overt hepatic encephalopathy after transjugular intrahepatic portosystemic shunt creation in patients with liver cirrhosis
2020 · Huan Tong, Can Gan, et al. · Journal of Digestive Diseases · 24
Liver sinusoidal endothelial cells contribute to portal hypertension through collagen type IV–driven sinusoidal remodeling
2024 · Can Gan, Usman Yaqoob, et al. · JCI Insight · 21
Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats
2021 · Shihang Tang, Zhiyin Huang, et al. · Life Sciences · 20
High HIF-1α expression predicts poor prognosis of patients with colon adenocarcinoma.
2018 · Zhi-Yin Huang, Lin-Hao Zhang, et al. · PubMed · 14
Telomere dysfunction promotes cholangiocyte senescence and biliary fibrosis in primary sclerosing cholangitis
2023 · Nidhi Jalan-Sakrikar, Abid Anwar, et al. · JCI Insight · 13
PDF
Atypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration
2023 · Tian Lan, Yang Tai, et al. · Inflammation and Regeneration · 10
PDF
High expression of long non-coding RNA Linc-A associates with poor survival in patients with colorectal cancer
2020 · Chong Zhao, Can Gan, et al. · Molecular Biology Reports · 8
Epigenetically controlled endothelial promyelocytic leukemia drives liver inflammation and fibrosis
2026 · Can Gan, Enjiang Lai, et al. · Journal of Clinical Investigation · 5
cGAS-STING signaling pathway in MASLD and liver fibrosis
2026 · Yang Xiao, Yufang Ma, et al. · Journal of Molecular Medicine · 4
Mo2029 – Octreotide Ameliorates Obesity-Induced Pancreatic Steatosis Via Srebp-1C Pathway
2019 · Can Gan, Cheng-Wei Tang, et al. · Gastroenterology · 1
601 – The Effect of Esomeprazole on the Duodenal Microbiota in Severe Acute Pancreatitis: A Prospective Randomized Controlled Stud
2019 · Xiao Ma, Zhiyin Huang, et al. · Gastroenterology · 1
Downregulation of COX-2 expression in liver sinusoidal endothelial cell prevented the formation of liver sinusoidal microthrombi through the AKT/mTOR/TSP-1 axis
2026 · Shuaijie Qian, Can Gan, et al. · Pharmacological Research
PDF
A unique case of gastrointestinal bleeding with splenomegaly
2025 · Can Gan, Shihang Tang · SAGE Open Medical Case Reports
OS-044 Liver sinusoidal endothelial cell BRD4 drives inflammatory angiocrine signaling in liver fibrosis
2025 · Can Gan, Enjiang Lai, et al. · Journal of Hepatology
OS-041 Nutritional therapy prevents overt hepatic encephalopathy (OHE) in patients with cirrhosis after transjugular intrahepatic portosystemic shunt (TIPS): a randomized controlled trial
2025 · Ying Li, Xin Quan, et al. · Journal of Hepatology
Mo1642: ENDOTHELIAL BRD4 DRIVES INFLAMMATORY MACROPHAGE INFILTRATION VIA TIMP1-MEDIATED ANGIOCRINE SIGNALING DURING LIVER FIBROSIS
2025 · Can Gan, Enjiang Lai, et al. · Gastroenterology
SAT-077 Prevention of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt by live combined Bifidobacterium and Lactobacillus tablets: a randomized controlled trial
2024 · Ying Li, Xin Quan, et al. · Journal of Hepatology
Works count: 31
Citation count: 952
H-index: 13
I10-index: 14
Year
Topic
Type